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Study reveals association between inadequate antioxidant intake and increased risk of depression in men

Disease Prevention Daily

2020 JUN 01 (NewsRx) -- By a News Reporter-Staff News Editor at Disease Prevention Daily -- A new study on Health and Medicine - Diet and Nutrition is now available. According to news reporting originating in Sydney, Australia, by NewsRx journalists, research stated, “The objectives of the study were to evaluate the associations between antioxidant intake, dietary patterns and depressive symptoms among older men. Method 794 men participated in a detailed diet history interview at the Concord Health and Ageing in Men Project 3rd wave (considered baseline nutrition) and 781 men participated at the 4th wave (considered 3-year follow-up).”

Funders for this research include National Health and Medical Research Council, Ageing and Alzheimers Institute, University of Sydney, Australian Research Council Centre of Excellence in Population Ageing Research.

The news reporters obtained a quote from the research from the University of Sydney, “Depressive symptoms were measured using the Geriatric Depression Scale (GDS >= 5). Dietary adequacy of antioxidant intake was assessed by comparing participants’ median intake of vitamin A, E, C and zinc to the Nutrient Reference Values for Australia. Attainment of NRVs of antioxidant was categorised into a dichotomised variable ‘poor’ (meeting <= 2) or ‘good’ (meeting >= 3). Individual antioxidant nutrient was categorised into quartiles. The Australian and Mediterranean diet scores were assessed as predictor variables. The prevalence of GDS >= 5 was 12.8% at baseline nutrition and 13.2% of men developed GDS >= 5 at a 3-year follow-up. There was a significant cross-sectional association between poor antioxidant intake and GDS >= 5 in adjusted analyses [OR: 1.95 (95% CI 1.03, 3.70)]. Poor antioxidant intake at baseline nutrition remained prospectively associated with incident GDS >= 5 [OR: 2.46 (95% CI 1.24, 4.88)] in adjusted analyses. This association was also found for the lowest quartile of zinc [OR 2.72 (95% CI 1.37, 5.42)] and vitamin E intake [OR 2.18 (95% CI 1.05, 4.51)]. None of the other antioxidants and dietary patterns had a significant association with incident depressive symptoms.”

According to the news reporters, the research concluded: “Inadequacy of antioxidant intake, particularly zinc and vitamin E, is associated with increased risk of clinically significant depressive symptoms in older men.”

For more information on this research see: The Association Between Antioxidant Intake, Dietary Pattern and Depressive Symptoms In Older Australian Men: the Concord Health and Ageing In Men Project. European Journal of Nutrition, 2020;():. European Journal of Nutrition can be contacted at: Springer Heidelberg, Tiergartenstrasse 17, D-69121 Heidelberg, Germany. (Springer - www.springer.com; European Journal of Nutrition - http://www.springerlink.com/content/1436-6207/)

Our news correspondents report that additional information may be obtained by contacting A. Das, University of Sydney, Charles Perkins Centre, School of Life and Environmental Sciences, Sydney, Nsw 2006, Australia. Additional authors for this research include R.V. Ribeiro, V. Hirani, R.G. Cumming, D.G. Le Couteur, D.J. Handelsman, V. Naganathan and L.M. Waite.

The direct object identifier (DOI) for that additional information is: https://doi.org/10.1007/s00394-020-02255-8. This DOI is a link to an online electronic document that is either free or for purchase, and can be your direct source for a journal article and its citation.

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