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Association between excess body mass and disturbances in mineral levels

Obesity Daily News

2020 OCT 19 (NewsRx) -- By a News Reporter-Staff News Editor at Obesity Daily News -- New study results on iodine deficiency have been published. According to news reporting out of Poznan, Poland, by NewsRx editors, research stated, “Obesity and excess body weight are significant epidemiological issues, not only because they are costly to treat, but also because they are among the leading causes of death worldwide. In 2016, an estimated 40% of the global population was overweight, reflecting the importance of the issue. Obesity is linked to metabolism malfunction and concomitantly with altered mineral levels in the body.”

Funders for this research include Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu.

The news reporters obtained a quote from the research from Poznan University of Medical Sciences: “In this paper, we review alterations in somatic levels of iron, calcium, magnesium, copper, iodine, chromium, selenium, and zinc in relation to excess body mass. An electronic literature search was performed using PubMed. Our search covered original English research articles published over the past five years, culminating in 63 papers included for study. The reviewed papers presented correlation between obesity and hypomagnesemia and hypozincemia. They also indicated that patients with excess body mass present increased body copper levels. Studies have similarly indicated that obesity appears to be associated with lower selenium levels in both blood and urine, which may be correlated with the decline and weakening of defenses against oxidative stress. It has been found that decreased level of chromium is connected with metabolic syndrome. Chromium supplementation influences body mass, but the effect of the supplementation depends on the chemical form of the chromium. It is hypothesized that obesity poses a risk of iodine deficiency and iodine absorption may be disrupted by increased fat intake in obese women. A range of studies have suggested that obesity is correlated with iron deficiency. On the other hand, some reports have indicated that excess body mass may coexist with iron excess. The relation between obesity and body iron level requires further investigation. Calcium signaling seems to be disturbed in obesity, due to the increased production of reactive oxygen species and low level of fast troponin isoform responsible for mediating calcium sensitivity of muscle relaxation. Correlation between excess body mass and calcium levels needs further research.”

According to the news editors, the research concluded: “Excess body mass is associated with alterations in mineral levels in the body, in particular hypomagnesemia and decreased selenium (Se) and zinc (Zn) levels. Chromium (Cr) deficiency is associated with metabolic syndrome. Obese patients are at risk of iodine deficiency. Excess body mass is associated with elevated levels of copper (Cu). Data on the association between obesity and iron (Fe) levels are contradictory. Obesity coexists with disturbed calcium (Ca) signaling pathways. The association between obesity and body Ca levels has not been investigated in detail.”

For more information on this research see: The Association between Excess Body Mass and Disturbances in Somatic Mineral Levels. International Journal of Molecular Sciences, 2020,21(7306):7306. (International Journal of Molecular Sciences - http://www.mdpi.com/journal/ijms). The publisher for International Journal of Molecular Sciences is MDPI AG.

A free version of this journal article is available at https://doi.org/10.3390/ijms21197306.

Our news journalists report that more information may be obtained by contacting Weronika Banach, Faculty of Medicine, Poznan University of Medical Sciences, Fredry St. 10, 61-701 Poznan, Poland. Additional authors for this research include Karolina Nitschke, Natalia Krajewska, Wojciech Mongiallo, Oskar Matuszak, Jozef Muszynski, Damian Skrypnik.

(Our reports deliver fact-based news of research and discoveries from around the world.)