Advanced Retinol Serum

1 fl oz Item # 80177

Advanced Retinol Serum

1 fl oz Item # 80177

Three innovative vitamin A compounds reduce the appearance of fine lines and wrinkles, balance skin pigmentation and encourage more vibrant, youthful-looking skin.

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Great product reasonably priced. I can notice improvement in just weeks.


I wake up with skin that looks smooth and refreshed.


My skin is really enjoying this serum. I bought one bottle as a trial and am going to get more because it has made a big difference in my skin.


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Advanced Retinol Serum

1 fl oz


We all want beautifully hydrated, healthy-looking skin. But time and the great outdoors can take their toll, causing everything from wrinkles to uneven pigmentation. Advanced Retinol Serum gradually releases three vitamin A derivatives into your skin, locking in moisture to support a more youthful looking you!

Smooth, youthful-looking skin requires hydration—these vitamin A derivatives help lock moisture in at the cellular level.

Advanced Retinol Serum Benefits

  • Helps brighten, rejuvenate, and revitalize skin cells
  • Uses innovative vitamin A to promote collagen production and reduce the appearance of fine lines and wrinkles
  • Helps maintain even skin pigmentation and color

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40 years of research dedicated to bringing you premium, scientifically-validated formulations.

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99% of our products are manufactured in the U.S, and a Certificate of Analysis is available for every product we produce.

Your skin naturally ages over time.1,2 The outer layer of your skin becomes thinner, which weakens its abilities as a natural barrier. This leads to moisture loss and leaves your skin vulnerable to the effects of the environment around you.3,4 But there are things you can do to revitalize your skin.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.


Apply a thin layer to your clean face twice weekly using fingertips in a circular motion until fully absorbed. Increase to nightly usage permitting skin tolerability. Make sure to apply SPF daily and limit sun exposure while using this product.


Keep out of reach of children. For external use only. Avoid contact with eyes. If product contacts eyes, rinse thoroughly. If rash or irritation occurs, discontinue use.


purified water, glycerin, butylene glycol, retinyl palmitate, retinol, hydroxypinacolone retinoate, sodium hyaluronate, tocopherol, ceramide NP, trideceth-6 phosphate, cyclopentasiloxane, cetearyl isononanoate, sodium polyacrylate, ceteareth-20, cetearyl alcohol, dimethicone, glyceryl stearate, cetyl palmitate, benzoic acid, ceteareth-12, sodium PCA, dimethyl isosorbide, caprylic/capric triglyceride, polysorbate 20, laureth-23, triethanolamine, ethylhexylglycerin, disodium EDTA, phenoxyethanol.

  1. Available at: InCosmetics/2015-Website/Documents/in-cos15,%20IS,%20 T2,D1,Granactive%20Retinoid%20The%20power%20of%20retinol%20 without%20the%20irritation,John%20Gormley.pdf. Accessed June 2, 2020.
  2. Farage MA, Miller KW, Elsner P, et al. Intrinsic and extrinsic factors in skin ageing: a review. Int J Cosmet Sci. 2008 Apr;30(2):87-95.
  3. Farage MA, Miller KW, Elsner P, et al. Characteristics of the Aging Skin. Adv Wound Care (New Rochelle). 2013 Feb;2(1):5-10.
  4. Fenske NA, Lober CW. Structural and functional changes of normal aging skin. J Am Acad Dermatol. 1986 Oct;15(4 Pt 1):571-85.
  5. Kafi R, Kwak HS, Schumacher WE, et al. Improvement of naturally aged skin with vitamin A (retinol). Arch Dermatol. 2007 May;143(5):606-12.
  6. Tucker-Samaras S, Zedayko T, Cole C, et al. A stabilized 0.1% retinol facial moisturizer improves the appearance of photodamaged skin in an eight-week, double-blind, vehicle-controlled study. J Drugs Dermatol. 2009 Oct;8(10):932-6.
  7. Truchuelo MT, Jimenez N, Miguel-Gomez L, et al. Histological and Immunohistochemical Evaluation of the Efficacy of a New Cosmetic Formulation in the Treatment of Skin Photoaging. Dermatol Res Pract. 2017;2017:8407247.
  8. Available at: Accessed June 2, 2020. 

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer



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