T3 uptake is an indirect measurement of available binding sites on thyroxine binding globulin; the protein that transports thyroid hormone in the blood. T3 uptake is not a measurement of T3 and should never be used alone. It is best used in conjunction with T4.
T3 uptake can be abnormal with thyroid dysfunction, malnutrition, and kidney disease.
Fasting is not required for this test. Take all medications as prescribed.
Abnormal T3 uptake can be seen with use of oral contraceptives and hormone prescriptions such as testosterone and estrogen.
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