Free Shipping on All Orders $75 Or More! Ends January 31st.

Your Trusted Brand for Over 35 Years

Health Protocols

Psoriasis

References

AAD. American Academy of Dermatology. Psoriasis: Who gets and causes. Available at: https://www.aad.org/dermatology-a-to-z/diseases-and-treatments/m---p/psoriasis . Copyright 2015. Accessed 8/21/2015.

Adamzik K, McAleer MA, Kirby B. Alcohol and psoriasis: sobering thoughts. Clin Exp Dermatol. 2013;38:819-822.

Addolorato G, Parente A, de Lorenzi, et al. Rapid regression of psoriasis in a coeliac patient after gluten-free diet. Digestion. 2003;68:9-12.

Ando N, Nakamura Y, Aoki R, Ishimaru K, Ogawa H, Okumura K, . . . Nakao A. Circadian Gene Clock Regulates Psoriasis-Like Skin Inflammation in Mice. The Journal of investigative dermatology. Aug 20 2015.

Andoh T, Kuraishi Y. Nitric oxide enhances substance P-induced itch-associated responses in mice. British journal of pharmacology. Jan 2003;138(1):202-208.

Antiga E, Bonciolini V, Volpi W, et al. Oral curcumin (Meriva) is effective as an adjuvant treatment and is able to reduce IL-22 serum levels in patients with psoriasis vulgaris. BioMed Research International. 2015;2015.

Archier E, Devaux S, Castela E, Gallini A, Aubin F, Le Maitre M, . . . Richard MA. Carcinogenic risks of psoralen UV-A therapy and narrowband UV-B therapy in chronic plaque psoriasis: a systematic literature review. Journal of the European Academy of Dermatology and Venereology: JEADV. May 2012;26 Suppl 3:22-31.

Armstrong AW. ePocrates. Psoriasis. http://online.epocrates/com/u/291174/Psoriasis. Last updated 11/14/2014. Accessed 9/18/2015.

Atwan A, Ingram JR, Abbott R, Kelson MJ, Pickles T, Bauer A, Piguet V. Oral fumaric acid esters for psoriasis. The Cochrane database of systematic reviews. 2015;8:Cd010497.

Axelsson J, Sundelin T, Ingre M, Van Someren EJ, Olsson A, Lekander M. Beauty sleep: experimental study on the perceived health and attractiveness of sleep deprived people. BMJ (Clinical research ed.). 2010;341:c6614.

Bachelez H, van de Kerkhof PC, Strohal R, Kubanov A, Valenzuela F, Lee JH, . . . Wolk R. Tofacitinib versus etanercept or placebo in moderate-to-severe chronic plaque psoriasis: a phase 3 randomised non-inferiority trial. Lancet. Aug 8 2015;386(9993):552-561.

Bagel J. Pipeline focus: IL-17. Practical Dermatology. 2012; pg. 46.

Bagel J. Emerging therapies in the evolving biologic platform for psoriasis treatment. Practical Dermatology. 2014;May; p. 38-42.

Bailey LB, Gregory JF. Folate Metabolism and Requirements. The Journal of nutrition. April 1, 1999;129(4):779-782.

Balbas GM, Regana MS, Millet PU. Study on the use of omega-3 fatty acids as a therapeutic supplement in treatment of psoriasis. Clinical, Cosmetic and Investigational Dermatology. 2011;4:73-77.

Balbis E, Patriarca S, Furfaro AL, et al.Whey proteins influence hepatic glutathione after CCI4 intoxication. Toxicol Ind Health. 2009;May-Jun;25(4-5):325-8.

Bahcetepe N, Kutlubay Z, Yilmaz E, et al. The role of HLA antigens in the aetiology of psoriasis. Med Glas (Zeneca). 2013;10(2):339-342.

Barrea L, Balato N, Di Somma C, et al. Nutrition and psoriasis: is there any association between the severity of the disease and adherence to the Mediterranean diet? J Transl Med. 2015;13:18.

Belcaro G, Cornelli U, Luzzi R, et al. Pycnogenol supplementation improves health risk factors in subjects with metabolic syndrome. Phytother Res. 2013;Oct;27(10):1572-8.

Belcaro G, Luzzi R, Hu S, et al. Improvement in signs and symptoms in psoriasis patients with pycnogenol supplementation. Panminerva Med. 2014;Mar;56(1):41-8.

Benson MM, Frishman WH. The Heartbreak of Psoriasis: A Review of Cardiovascular Risk in Patients With Psoriasis. Cardiology in review. Nov-Dec 2015;23(6):312-316.

Bernstein JE, Parish LC, Rapaport M, Rosenbaum MM, Roenigk HH, Jr. Effects of topically applied capsaicin on moderate and severe psoriasis vulgaris. Journal of the American Academy of Dermatology. Sep 1986;15(3):504-507.

Bhatia BK, Millsop JW, Debbaneh M, et al. Diet and psoriasis: part 2. celiac disease and role of a gluten-free diet. J Am Acad Dermatol. 2014;Aug;71(2):350-358.

Boca AN, Tataru A, Buzoianu AD, Pincelli C, Socaciu C. Pharmacological Benefits of Herbal Formulations in the Management of Psoriasis vulgaris. Not Bot Horti Agrobo. 2014;42(1):1-8.

Bode AM, Dong Z. The two faces of capsaicin. Cancer research. Apr 15 2011;71(8):2809-2814.

Boehncke S, Fichtlscherer S, Salgo R, Garbaraviciene J, Beschmann H, Diehl S, . . . Boehncke WH. Systemic therapy of plaque-type psoriasis ameliorates endothelial cell function: results of a prospective longitudinal pilot trial. Archives for dermatological research. Archiv fur dermatologische Forschung. Aug 2011;303(6):381-388.

Bonnefont-Rousselot D. Obesity and oxidative stress: potential roles of melatonin as antioxidant and metabolic regulator. Endocrine, metabolic & immune disorders drug targets. 2014;14(3):159-168.

Borriello A, Bencivenga D, Caldarelli I, Tramontano A, Borgia A, Zappia V, Della Ragione F. Resveratrol: from basic studies to bedside. Cancer treatment and research. 2014;159:167-184.

Bosmansky K, Trnavsky K. Psoriasis and gout: report of 4 cases. Clinical rheumatology. Dec 1983;2(4):423-426.

Bowcock AM. The genetics of psoriasis and autoimmunity. Annual review of genomics and human genetics. 2005;6:93-122.

Boyd AS, King LE, Jr. Tamoxifen-induced remission of psoriasis. Journal of the American Academy of Dermatology. Nov 1999;41(5 Pt 2):887-889.

Brenner M, Hearing VJ. The protective role of melanin against UV damage in human skin. Photochemistry and photobiology. May-Jun 2008;84(3):539-549.

Brunoni AR, Santos IS, Sabbag C, Lotufo PA, Bensenor IM. Psoriasis severity and hypothalamic-pituitary-adrenal axis function: results from the CALIPSO study. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.]. Dec 2014;47(12):1102-1106.

Busse K, Liao W. Which Psoriasis Patients Develop Psoriatic Arthritis? Psoriasis forum / National Psoriasis Foundation. Winter 2010;16(4):17-25.

Cai Y, Fleming C, Yan J. New insights of T cells in the pathogenesis of psoriasis. Cellular & molecular immunology. 2012;9(4):302-309.

Carboni I, De Felice C, De Simoni I, Soda R, Chimenti S. Fumaric acid esters in the treatment of psoriasis: an Italian experience. The Journal of dermatological treatment. Jan 2004;15(1):23-26.

Carroll J. FierceBiotech. UPDATED: Suicide stunner prompts Amgen to dump brodalumab, denting AstraZeneca's rep. http://www.fiercebiotech.com/story/suicide-stunner-prompts-amgen-dump-brodalumab-psoriasis-walk-away-astrazene/2015-05-23. 5/23/2015. Accessed 12/21/2015.

Chandrashekar L, Kumari GRK, Rajappa M, et al. 25-hydroxy vitamin D and ischaemia-modified albumin levels in psoriasis and their association with disease severity. Br J Biomed Sci. 2015;72(2):56-60.

Chen ZQ, Mo ZN. [Curcumin in the treatment of prostatic diseases]. Zhonghua nan ke xue = National journal of andrology. Jan 2008;14(1):67-70.

Chern E, Yau D, Ho JC, Wu WM, Wang CY, Chang HW, Cheng YW. Positive effect of modified Goeckerman regimen on quality of life and psychosocial distress in moderate and severe psoriasis. Acta dermato-venereologica. Jun 2011;91(4):447-451.

Chimenti MS, Triggianese P, Nuccetelli M, Terracciano C, Crisanti A, Guarino MD, . . . Perricone R. Auto-reactions, autoimmunity and psoriatic arthritis. Autoimmunity reviews. Dec 2015;14(12):1142-1146.

Chiricozzi A, Chimenti S. Effective Topical Agents and Emerging Perspectives in the Treatment of Psoriasis: Keratolytics. Expert Rev Dermatol. 2012;7(3):283-293.

Choudhry SZ, Bhatia N, Ceilley R, et al. Role of oral Polypodium leucotomos extract in dermatologic diseases: a review of the literature. J Drugs Dermatol. 2014;Feb;13(2):148-53.

Chrubasik S, Weiser T, Beime B. Effectiveness and safety of topical capsaicin cream in the treatment of chronic soft tissue pain. Phytotherapy research: PTR. Dec 2010;24(12):1877-1885.

Das RP, Jain AK, Ramesh V. Current concepts in the pathogenesis of psoriasis. Indian J Dermatol. 2009;54(1):7-12.

Dawn A, Yosipovitch G. Treating itch in psoriasis. Dermatology nursing / Dermatology Nurses' Association. Jun 2006;18(3):227-233.

Declercq SD, Pouliot R. Promising new treatments for psoriasis. The Scientific World. 2013;2013.

Delves PJ. Merck Manual Professional Edition. Human Leukocyte Antigen (HLA) System. Available at: http://www.merckmanuals.com/professional/immunology-allergic-disorders/biology-of-the-immune-system/human-leukocyte-antigen-hla-system . Last updated: 11/2014. Accessed 8/10/2015.

de Miguel R, el-Azhary R. Efficacy, safety, and cost of Goeckerman therapy compared with biologics in the treatment of moderate to severe psoriasis. International journal of dermatology. Jun 2009;48(6):653-658.

Dennis M, Bhutani T, Koo J, Liao W. Goeckerman therapy for the treatment of eczema: a practical guide and review of efficacy. The Journal of dermatological treatment. Feb 2013;24(1):2-6.

Dominguez-Rodriguez A. Melatonin in cardiovascular disease. Expert opinion on investigational drugs. Nov 2012;21(11):1593-1596.

Doukaki S, Caputo V, Bongiorno MR. Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients. Dermatol Res Pract. 2013;2013:389031.

Dowlatshahi EA, van der Voort EAM, Arends LR, et al. Markers of systemic inflammation in psoriasis: a systematic review and meta-analysis. Br J Dermatol. 2013;169:266-282.

Dunn B. Center for Drug Evaluation And Research. Cross-Discipline Team Leader Review. http://www.accessdata.fda.gov/drugsatfda_docs/nda/2013/204063Orig1s000SumR.pdf. 2/11/13. Accessed 1/14/2016.

Eder L, Chandran V, Gladman DD. What have we learned about genetic susceptibility in psoriasis and psoriatic arthritis? Curr Opin Rheumatol. 2015;Jan;27(1):91-8.

Ellis CN, Berberian B, Sulica VI, Dodd WA, Jarratt MT, Katz HI, . . . Wolf JE. A double-blind evaluation of topical capsaicin in pruritic psoriasis. Journal of the American Academy of Dermatology. Sep 1993;29(3):438-442.

Elsevier BV. First Consult. Psoriatic arthritis. www.clinicalkey.com. Accessed 9/24/2015.

Eppinga H, Konstantinov SR, Peppelenbosch MP, et al. The microbiome and psoriatic arthritis. Curr Rheumatol Rep. 2014;16:407.

Esposito E, Cuzzocrea S. Antiinflammatory activity of melatonin in central nervous system. Current neuropharmacology. Sep 2010;8(3):228-242.

European Commission. REPORT OF THE SCIENTIFIC COMMITTEE ON ANIMAL NUTRITION ON THE SAFETY OF FUMARIC ACID. 2003.

Fala L. American Health & Drug Benefits. Vol. 8, 6th Annual Payers' Guide. Otezla (Apremilast), an Oral PDE-4 Inhibitor, Receives FDA Approval for the Treatment of Patients with Active Psoriatic Arthritis and Plaque Psoriasis. http://www.ahdbonline.com/issues/2015/march-2015-vol-8-sixth-annual-payers-guide/1883-otezla-apremilast-an-oral-pde-4-inhibitor-receives-fda-approval-for-the-treatment-of-patients-with-active-psoriatic-arthritis-and-plaque-psoriasis. Last updated 12/4/2015. Accessed 12/4/2015.

FDA. U.S. Food and Drug Administration. News & Events page. FDA News Release: FDA approves Otezla to treat psoriatic arthritis. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm390091.htm. Last updated 3/24/2014. Accessed 12/4/2015.

FDA. U.S. Food and Drug Administration. FDA News Release. FDA approves new psoriasis drug Cosentyx. Available at: http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm430969.htm . Last updated: January, 2015. Accessed 8/15/2015.

Federman DG, Froelich CW, Kirshner RS. Topical Psoriasis Therapy. Am Fam Phycian. 1999;59(4):957-962. http://www.aafp.org/afp/1999/0215/p957.html.

Ferreira CM, Vieira AT, Vinolo MAR, et al. The central role of the gut microbiota in chronic inflammatory diseases. J Immunol Res. 2014;2014.

Ferri FF. Ferri's Clinical Advisor. Psoriasis. www.clinicalkey.com. Copyright 2015. Accessed 9/18/2015.

Fiala Z, Borska L, Pastorkova A, Kremlacek J, Cerna M, Smejkalova J, Hamakova K. Genotoxic effect of Goeckerman regimen of psoriasis. Archives for dermatological research. Archiv fur dermatologische Forschung. Oct 2006;298(5):243-251.

Finamor DC, Sinigaglia-Coimbra R, Neves LCM, et al. A pilot study assessing the effect of prolonged administration of high daily doses of vitamin D on the clinical course of vitiligo and psoriasis. Dermato-Endocrinology. 2013;5(1): 222-234.

Fleming P, Kraft J, Gulliver WP, et al. The relationship of obesity with the severity of psoriasis: a systematic review. J Cutan Med Surg. 2015;19(5):450-456.

Foster M, Samman S. Zinc and regulation of inflammatory cytokines: implications for cardiometabolic disease. Nutrients. 2012;4:676-694.

Fry L, Baker BS, Powles AV, Engstrand L. Psoriasis is not an autoimmune disease? Experimental dermatology. Apr 2015;24(4):241-244.

Furuhashi T, Saito C, Torii K, Nishida E, Yamazaki S, Morita A. Photo(chemo)therapy reduces circulating Th17 cells and restores circulating regulatory T cells in psoriasis. PloS one. 2013;8(1):e54895.

Garcia-Pérez ME, Stevanovic T, Poubelle PE. New therapies under development for psoriasis treatment. Curr Opin Pediatr. 2013;25:480-487.

Gelfand JM, Neimann AL, Shin DB, et al. Risk of myocardial infarction in patients with psoriasis. JAMA. 2006;296(14):1735-1741.

Geuking MB, Koller Y, Rupp S, et al. The interplay between the gut microbiota and the immune system. Gut Microbes 2014;5(3):411-418.

Girolomoni G, Gisondi P. Psoriasis and systemic inflammation: underdiagnosed enthesopathy. JEADV. 2009;23(Suppl. 1):3-8.

Gisondi P, Rossini M, Di Cesare A, et al. Vitamin D status in patients with chronic plaque psoriasis. Br J Dermatol. 2012;Mar;166(3):505-10.

Gisondi P, Fantin F, Del Giglio M, Valbusa F, Marino F, Zamboni M, Girolomoni G. Chronic plaque psoriasis is associated with increased arterial stiffness. Dermatology (Basel, Switzerland). 2009;218(2):110-113.

Gold Standard. Drug Monograph. Methotrexate. www.clinicalkey.com. Last updated 10/19/2015. Accessed 12/4/2015.

Goldman L, Schafer AI. Goldman Cecil Medicine, Twenty-Fourth Edition. Psoriatic arthritis; Spondyloarthropathies. Copyright 2016 by Saunders, an imprint of Elsevier, Inc. www.clinicalkey.com. Accessed 9/24/2015.

Gollnick H, Altmeyer P, Kaufmann R, Ring J, Christophers E, Pavel S, Ziegler J. Topical calcipotriol plus oral fumaric acid is more effective and faster acting than oral fumaric acid monotherapy in the treatment of severe chronic plaque psoriasis vulgaris. Dermatology (Basel, Switzerland). 2002;205(1):46-53.

Gonzalez S, Gilaberte Y, Philips N, et al. Fernblock, a nutraceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers. Int J Mol Sci. 2011;12:8466-8475.

Gooderham M. Small molecules: an overview of emerging therapeutic options in the treatment of psoriasis. Skin Therapy Lett. 2013;Nov-Dec;18(7):1-4.

Gordon KB, Langley RG, Gottlieb AB, et al. A phase III, randomized, controlled trial of the fully human IL-12/23 mAb briakinumab in moderate-to-severe psoriasis. J Invest Dermatol. 2012;132:304-314.

Goyal A, Terry PD, Superak HM, Nell-Dybdahl CL, Chowdhury R, Phillips LS, Kutner MH. Melatonin supplementation to treat the metabolic syndrome: a randomized controlled trial. Diabetol Metab Syndr. 2014;6:124.

Grether-Beck S, Marini A, Jaenicke T, Krutmann J. French Maritime Pine Bark Extract (Pycnogenol®) Effects on Human Skin: Clinical and Molecular Evidence. Skin Pharmacology and Physiology. 2016;29(1):13-17.

Groeger D, O’Mahony L, Murphy EF, et al. Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut. Gut Microbes. 2013;4(4):325-339.

Grozdev I, Korman N, Tsankov N. Psoriasis as a systemic disease. Clinics in Dermatology. 2014;32:343-350.

Gudjonsson JE, Thorarinsson AM, Sigurgeirsson B, et al. Streptococcal throat infections and exacerbation of chronic plaque psoriasis: a prospective study. Br J Dermatol. 2003;149:530-534.

Gulati OP. Pycnogenol in metabolic syndrome and related disorders. Phyother Res. 2015;29:949-968.

Gupta R, Debbaneh MG, Liao W. Genetic epidemiology of psoriasis. Curr Dermatol Rep. 2014;3(1):61-78.

Gupta R, Debbaneh M, Butler D, Huynh M, Levin E, Leon A, . . . Liao W. The Goeckerman regimen for the treatment of moderate to severe psoriasis. Journal of visualized experiments : JoVE. 2013(77):e50509.

Hall HA. Ferri's Clinical Advisor. Psoriatic Arthritis. www.clinicalkey.com. Copyright 2015. Accessed 9/18/2015.

Hall JM, Cruser D, Podawiltz A, Mummert DI, Jones H, Mummert ME. Psychological Stress and the Cutaneous Immune Response: Roles of the HPA Axis and the Sympathetic Nervous System in Atopic Dermatitis and Psoriasis. Dermatol Res Pract. 2012;2012:403908.

Harari M, Czarnowicki T, Fluss R, Ruzicka T, Ingber A. Patients with early-onset psoriasis achieve better results following Dead Sea climatotherapy. Journal of the European Academy of Dermatology and Venereology : JEADV. May 2012;26(5):554-559.

He DY, Dai SM. Anti-inflammatory and immunomodulatory effects of Paeonia lactiflora Pall., a traditional Chinese herbal medicine. Front Pharmacol. 2011;2:1-5.

Hebert HL, Ali FR, Bowes J, et al. Genetic susceptibility to psoriasis and psoriatic arthritis: implications for therapy. Br J Dermatol. 2012;166(3):474-82.

Heier I, Søyland E, Krogstad AL, et al. Sun exposure rapidly reduces plasmacytoid dendritic cells and inflammatory dermal dendritic cells in psoriatic skin. Br J Dermatol. 2011;165:792-801.

Higdon J. Oregon State University. Linug Pauling Institute. Micronutrient Information Center. Folate. http://lpi.oregonstate.edu/mic/vitamins/folate. Last updated 6/2014a. Accessed 12/4/2015.

Higdon J. Oregon State University. Linus Pauling Institute. Micronutrient Information Center. Vitamin D. http://lpi.oregonstate.edu/mic/vitamins/vitamin-D#supplements. Last updated 7/2014b. Accessed 12/7/2015.

Hirotsu C, Rydlewski M, Araujo MS, Tufik S, Andersen ML. Sleep loss and cytokines levels in an experimental model of psoriasis. PloS one. 2012;7(11):e51183.

Hossein-nezhad A, Holick MF. Vitamin D for health: a global perspective. Mayo Clin Proc. 2013;88(7):720-755.

HQO. Health Quality Ontario. Ultraviolet Phototherapy Management of Moderate-to-Severe Plaque Psoriasis: An Evidence-Based Analysis. Ont Health Technol Assess Ser. 2009;9(27):1-66.

Hunter HJ, Griffiths CE, Kleyn CE. Does psychosocial stress play a role in the exacerbation of psoriasis? Br J Dermatol. Nov 2013;169(5):965-974.

IFPMA. International Federation of Pharmaceutical Manufacturers & Associations. Bringing Psoriasis Into the Light. http://www.ifpma.org/fileadmin/content/Publication/2014/Psoriasis_Publication-Web.pdf. Accessed 12/3/2015.

Jani M, Barton A, Ho P. Pharmacogenetics of treatment response in psoriatic arthritis. Current rheumatology reports. Jul 2015;17(7):44.

Jariwala SP. The role of dendritic cells in the immunopathogenesis of psoriasis. Archives of Dermatological Research.

2007;299(8):359-366.

Juhlin L, Edqvist LE, Ekman LG, Ljunghall K, Olsson M. Blood glutathione-peroxidase levels in skin diseases: effect of selenium and vitamin E treatment. Acta dermato-venereologica. 1982;62(3):211-214.

Juzeniene A, Stokke KT, Thune P, et al. Pilot study of folate status in healthy volunteers and in patients with psoriasis before and after UV exposure. J Photochem Photobiol B. 2010;101(2):111-6.

Kahan V, Andersen ML, Tomimori J, Tufik S. Can poor sleep affect skin integrity? Medical hypotheses. Dec 2010;75(6):535-537.

Kamangar F, Neuhaus IM, Koo JYM. An evidence-based review of skin cancer rates on biologic therapies. J Dermatolog Treat. 2012;23:305-315.

Kamangar F, Koo J, Heller M, et al. Oral vitamin D, still a viable treatment option for psoriasis. J Dermatolog Treat. 2013;24:261-267.

Kartha LB, Chandrashekar L, Rajappa M, Menon V, Thappa DM, Ananthanarayanan PH. Serum melatonin levels in psoriasis and associated depressive symptoms. Clinical chemistry and laboratory medicine : CCLM / FESCC. Jun 2014;52(6):e123-125.

Kaukinen K, Partanen J, Maki M, Collin P. HLA-DQ typing in the diagnosis of celiac disease. The American journal of gastroenterology. Mar 2002;97(3):695-699.

Kazandjieva J, Grozdev I, Darlenski R, Tsankov N. Climatotherapy of psoriasis. Clinics in dermatology. Sep-Oct 2008;26(5):477-485.

Kharaeva Z, Gostova E, De Luca C, et al. Clinical and biochemical effects of coenzyme Q10, vitamin E, and selenium supplementation to psoriasis patients. Nutrition. 2009;25:295-302.

Kim GK. The rationale behind topical vitamin d analogs in the treatment of psoriasis: where does topical calcitriol fit in? The Journal of clinical and aesthetic dermatology. Aug 2010;3(8):46-53.

Kirke SM, Lowder S, Lloyd JJ, Diffey BL, Matthews JN, Farr PM. A randomized comparison of selective broadband UVB and narrowband UVB in the treatment of psoriasis. The Journal of investigative dermatology. Jul 2007;127(7):1641-1646.

Kjaer TN, Thorsen K, Jessen N, et al. Resveratrol ameliorates imiquimod-induced psoriasis-like skin inflammation in mice. PLoS One. 2015;10(5):e0126599.

Klein A, Schiffner R, Schiffner-Rohe J, Einsele-Kramer B, Heinlin J, Stolz W, Landthaler M. A randomized clinical trial in psoriasis: synchronous balneophototherapy with bathing in Dead Sea salt solution plus narrowband UVB vs. narrowband UVB alone (TOMESA-study group). Journal of the European Academy of Dermatology and Venereology : JEADV. May 2011;25(5):570-578.

Kloek J, Mortaz E, Van Ark I, et al. A whey-based glutathione-enhancing diet decreases allergen-induced airway contraction in a guinea-pig model of asthma. Br J Nutr. 2011;105(10):1465-70.

Kokcam I, Naziroglu M. Antioxidanst and lipid peroxidation status in the blood of patients with psoriasis. Clin Chim Acta. 1999;289(1-2):23-31.

Koo JY, Lowe NJ, Lew-Kaya DA, Vasilopoulos AI, Lue JC, Sefton J, Gibson JR. Tazarotene plus UVB phototherapy in the treatment of psoriasis. Journal of the American Academy of Dermatology. Nov 2000;43(5 Pt 1):821-828.

Kopel E, Levi A, Harari M, Ruzicka T, Ingber A. Effect of the Dead Sea climatotherapy for psoriasis on quality of life. The Israel Medical Association journal : IMAJ. Feb 2013;15(2):99-102.

Kozub P, Simaljakova M. Systemic therapy of psoriasis: methotrexate. Bratislavske lekarske listy. 2011;112(7):390-394.

Kurd SK, Troxel AB, Crits-Christoph P, Gelfand JM. The risk of depression, anxiety, and suicidality in patients with psoriasis: a population-based cohort study. Archives of dermatology. Aug 2010;146(8):891-895.

Lee E, Koo J. Modern modified 'ultra' Goeckerman therapy: a PASI assessment of a very effective therapy for psoriasis resistant to both prebiologic and biologic therapies. The Journal of dermatological treatment. Apr 2005;16(2):102-107.

Lee S, Mendelsohn A, Sarnes E. The burden of psoriatic arthritis: a literature review from a global health systems perspective. P & T : a peer-reviewed journal for formulary management. Dec 2010;35(12):680-689.

Lee MS, Lin RY, Chang YT, et al. The risk of developing non-melanoma skin cancer, lymphoma and melanoma in patients with psoriasis in Taiwan: a 10-year, population-based cohort study. Int J Dermatol. 2012;51:1454-1460.

Leonardi C, Matheson R, Zachariae C, Cameron G, Li L, Edson-Heredia E, . . . Banerjee S. Anti-interleukin-17 monoclonal antibody ixekizumab in chronic plaque psoriasis. The New England journal of medicine. Mar 29 2012;366(13):1190-1199.

Leung D, Travers J, Giorno R, Norris D, Skinner R, Aelion J, . . . Kotb M. Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis. Journal of Clinical Investigation. 1995;96(5):2106.

Levy LL, Solomon SM, Emer JJ. Biologics in the treatment of psoriasis and emerging new therapies in the pipeline. Psoriasis: Targets and Therapy. 2012;2:29-43.

Li WQ, Han JL, Chan AT, et al. Psoriasis, psoriatic arthritis and increased risk of incident Crohn’s disease in US women. Ann Rheum Dis. 2013;72(7):1200-1205.

Li W, Han J, Qureshi AA. Obesity and risk of incident psoriatic arthritis in US women. Annals of the rheumatic diseases. Aug 2012;71(8):1267-1272.

Li W, Qureshi AA, Schernhammer ES, Han J. Rotating night shift work and risk of psoriasis in US women. The Journal of investigative dermatology. 08/30 2013;133(2):565-567.

Liu JT, Yeh HM, Liu SY, Chen KT. Psoriatic arthritis: Epidemiology, diagnosis, and treatment. World journal of orthopedics. Sep 18 2014;5(4):537-543.

Liew SC, Das-Gupta E, Chakravarthi S, et al. Differential expression of the angiogenesis growth factors in psoriasis vulgaris. BMC Research Notes. 2012;5:201.

Love TJ, Zhu Y, Zhang Y, Wall-Burns L, Ogdie A, Gelfand JM, Choi HK. Obesity and the risk of psoriatic arthritis: a population-based study. Annals of the rheumatic diseases. Aug 2012;71(8):1273-1277.

Ludwig RJ, Herzog C, Rostock A, Ochsendorf FR, Zollner TM, Thaci D, . . . Boehncke WH. Psoriasis: a possible risk factor for development of coronary artery calcification. Br J Dermatol. Feb 2007;156(2):271-276.

Luftl M, Rocken M, Plewig G, et al. PUVA inhibits DNA replication, but not gene transcription ay nonlethal dosages. J Invest Dermatol. 1998;111:399-405.

Lundquist LM, Cole SW, Sikes ML. Efficacy and safety of tofacitinib for treatment of rheumatoid arthritis. World journal of orthopedics. Sep 18 2014;5(4):504-511.

Majewski S, Jablonska S. Do epidermodysplasia verruciformis human papillomaviruses contribute to malignant and benign epidermal proliferations? Archives of dermatology. May 2002;138(5):649-654.

Majewski S, Jablonska S. Possible involvement of epidermodysplasia verruciformis human papillomaviruses in the immunopathogenesis of psoriasis: a proposed hypothesis. Experimental dermatology. Dec 2003;12(6):721-728.

Malerba M, Gisondi P, Radaeli A, et al. Plasma homocysteine and folate levels in patients with chronic plaque psoriasis. Bt J Dermatol. 2006;155(6):1165-9.

Mallbris L, Wolk K, Sanchez F, et al. HLA-Cw0602 associates with a twofold higher prevalence of positive streptococcal throat swab at the onset of psoriasis: a case control study. BMC Dermatol. 2009;9:5.

Mansouri Y, Goldenberg G. Biologic safety in psoriasis: review of long-term safety data. The Journal of clinical and aesthetic dermatology. Feb 2015;8(2):30-42.

Mathur P, Ding Z, Saldeen T, Mehta JL. Tocopherols in the Prevention and Treatment of Atherosclerosis and Related Cardiovascular Disease. Clinical cardiology. Sep 2015;38(9):570-576.

Mayo Clinic. Diseases and Conditions. Definition. http://www.mayoclinic.org/diseases-conditions/psoriasis/basics/definition/con-20030838. 6/17/2015. Accessed 12/21/2015.

McDonald I, Connolly M, Tobin AM. A review of psoriasis, a known risk factor for cardiovascular disease and its impact on folate and homocysteine metabolism. J Nutr Metab. 2012;2012.

McFadden RT, Larmonier CB, Shehab KW, Midura-Kiela M, Ramalingam R, Harrison CA, . . . Kiela PR. The Role of Curcumin in Modulating Colonic Microbiota During Colitis and Colon Cancer Prevention. Inflamm Bowel Dis. Jul 25 2015.

Menter A, Cram DL. The Goeckerman regimen in two psoriasis day care centers. Journal of the American Academy of Dermatology. Jul 1983;9(1):59-65.

Menter A, Korman NJ, Elmets CA, Feldman SR, Gelfand JM, Gordon KB, . . . Bhushan R. Guidelines of care for the management of psoriasis and psoriatic arthritis. Section 3. Guidelines of care for the management and treatment of psoriasis with topical therapies. Journal of the American Academy of Dermatology. Apr 2009;60(4):643-659.

Middelkamp-Hup MA, Pathak MA, Parrado C, et al. Orally administered Polypodium leucotomos extract decreases psoralen-UVA-induced phototoxicity, pigmentation, and damage of human skin. J Am Acad Dermatol. 2004;50(1):41-9.

Migita K, Izumi Y, Jiuchi Y, Kozuru H, Kawahara C, Izumi M, . . . Kawakami A. Effects of Janus kinase inhibitor tofacitinib on circulating serum amyloid A and interleukin-6 during treatment for rheumatoid arthritis. Clinical and experimental immunology. Feb 2014;175(2):208-214.

Miller WL, Portale AA. Vitamin D 1 alpha-hydroxylase. Trends in endocrinology and metabolism: TEM. Oct 2000;11(8):315-319.

Millsop JW, Bhatia BK, Debbaneh M, Koo J, Liao W. Diet and Psoriasis: Part 3. Role of Nutritional Supplements. Journal of the American Academy of Dermatology. 04/26 2014;71(3):561-569.

Monteleone G, Pallone F, MacDonald TT, et al. Psoriasis: from pathogenesis to novel therapeutic approaches. Clin Sci (Lond). 2011;120(1):1-11.

Morris MS. Homocysteine and Alzheimer's disease. The Lancet. Neurology. Jul 2003;2(7):425-428.

Morrow T, Felcone LH. Defining the difference: What Makes Biologics Unique. Biotechnology healthcare. Sep 2004;1(4):24-29.

Mozzanica N, Tadini G, Radaelli A, Negri M, Pigatto P, Morelli M, . . . et al. Plasma melatonin levels in psoriasis. Acta dermato-venereologica. 1988;68(4):312-316.

Naldi L, Rzany B. Psoriasis (chronic plaque). BMJ clinical evidence. 2009;2009.

Navarro-Alarcon M, Ruiz-Ojeda FJ, Blanca-Herrera RM, MM AS, Acuna-Castroviejo D, Fernandez-Vazquez G, Agil A. Melatonin and metabolic regulation: a review. Food & function. Nov 2014;5(11):2806-2832.

Naziroglu M, Yildiz K, Tamturk B, et al. Selenium and psoriasis. Biol Trace Elem Res. 2012;150:3-9.

Nettelblad H, Vahlqvist C, Krysander L, Sjoberg F. Psoralens used for cosmetic sun tanning: an unusual cause of extensive burn injury. Burns : journal of the International Society for Burn Injuries. Dec 1996;22(8):633-635.

NHMRC. Australian National Health and Medical Research Council. Nutrient Reference Values for Australia and New Zealand. Vitamin E. Available at: https://www.nrv.gov.au/nutrients/vitamin-e. Last updated: September 2006. Accessed 8/25/2015.

Ni C, Chiu MW. Psoriasis and comorbidities: links and risks. Clinical, Cosmetic and Investigational Dermatology. 2014;7:119-132.

NIH. National Institutes of Health. National Institute of Arthritis and Musculoskeletal and Skin Diseases. Psoriasis. Questions and Answers about Psoriasis. Available at: http://www.niams.nih.gov/Health_Info/Psoriasis/. Last updated: October 2013. Accessed 8/5/2015.

NIH. National Institutes of Health. Melatonin: What You Need To Know. https://nccih.nih.gov/sites/nccam.nih.gov/files/Get_The_Facts_Melatonin_05-12-2015.pdf . Last updated 5/2015. Accessed 1/26/2016.

NLM. U.S. National Library of Medicine. Psoriatic Arthritis. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0024497/. Accessed 12/3/2015.

NPF. National Psoriasis Foundation. Moderate to Severe Psoriasis and Psoriatic Arhtritis: Biologic Drugs. 2015b.

NPF. National Psoriasis Foundation. Over-the-counter (OTC) Topicals. 2015a.

OSU. Oregon State University. Linus Pauling Institute. Micronutrient Information Center. Resveratrol. Available at: http://lpi.oregonstate.edu/mic/dietary-factors/phytochemicals/resveratrol . Last updated: 6/1//2015. Accessed 9/2/2015.

Overbergh L, Decallonne B, Valckx D, Verstuyf A, Depovere J, Laureys J, . . . Mathieu C. Identification and immune regulation of 25-hydroxyvitamin D-1-alpha-hydroxylase in murine macrophages. Clinical and experimental immunology. Apr 2000;120(1):139-146.

Oyetakin-White P, Suggs A, Koo B, Matsui MS, Yarosh D, Cooper KD, Baron ED. Does poor sleep quality affect skin ageing? Clinical and experimental dermatology. Jan 2015;40(1):17-22.

Padhi T, Garima. Metabolic syndrome and skin: psoriasis and beyond. Indian J Dermatol. 2013;58(4):299-305.

Palomino OM. Current knowledge in Polypodium leucotomos effect on skin protection. Arch Dermatol Res. 2015;307:199-209.

PAPAA. The Psoriasis and Psoriatic Alliance. Psoriasis and the Sun. http://www.papaa.org/further-information/psoriasis-and-sun. Accessed 12/10/2015.

Papp K, Reich K, Leonardi CL, Kircik L, Chimenti S, Langley RG, . . . Griffiths CE. Apremilast, an oral phosphodiesterase 4 (PDE4) inhibitor, in patients with moderate to severe plaque psoriasis: Results of a phase III, randomized, controlled trial (Efficacy and Safety Trial Evaluating the Effects of Apremilast in Psoriasis [ESTEEM] 1). Journal of the American Academy of Dermatology. Jul 2015;73(1):37-49.

Papp KA, Leonardi C, Menter A, Ortonne JP, Krueger JG, Kricorian G, . . . Baumgartner S. Brodalumab, an anti-interleukin-17-receptor antibody for psoriasis. The New England journal of medicine. Mar 29 2012;366(13):1181-1189.

Parisi R, Symmons DP, Griffiths CE, et al. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J Invest Dermatol. 2013;133(2):377-385.

Patel M, Day A, Warren RB, et al. Emerging therapies for the treatment of psoriasis. Dermatol Ther (Heidelb). 2012;2(1):16.

Patel T, Ishiuji Y, Yosipovitch G. Nocturnal itch: why do we itch at night? Acta dermato-venereologica. 2007;87(4):295-298.

Paul C, Cather J, Gooderham M, Poulin Y, Mrowietz U, Ferrandiz C, . . . Gottlieb AB. Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate to severe plaque psoriasis over 52 weeks: a phase III, randomized, controlled trial (ESTEEM 2). Br J Dermatol. Sep 10 2015.

Paul CF, Ho VC, McGeown C, Christophers E, Schmidtmann B, Guillaume JC, . . . Dubertret L. Risk of malignancies in psoriasis patients treated with cyclosporine: a 5 y cohort study. The Journal of investigative dermatology. Feb 2003;120(2):211-216.

Pearce DJ, Stealey KH, Balkrishnan R, Fleischer AB, Jr., Feldman SR. Psoriasis treatment in the United States at the end of the 20th century. International journal of dermatology. Apr 2006;45(4):370-374.

Pirro M, Stingeni L, Vaudo G, Mannarino MR, Ministrini S, Vonella M, . . . Mannarino E. Systemic inflammation and imbalance between endothelial injury and repair in patients with psoriasis are associated with preclinical atherosclerosis. European journal of preventive cardiology. Aug 2015;22(8):1027-1035.

Pittelkow MR, Perry HO, Muller SA, Maughan WZ, O'Brien PC. Skin cancer in patients with psoriasis treated with coal tar. A 25-year follow-up study. Archives of dermatology. Aug 1981;117(8):465-468.

Prussick R, Prussick L, Gutman J. Psoriasis improvement in patients using glutathione-enhancing, nondenatured whey protein isolate: a pilot study. J Clin Aesthet Dermatol. 2013;6(10):23-26.

Pujari V, Ireddy S, Itagi I, et al. The serum levels of malondialdehyde, vitamin E and erythrocyte catalase activity in psoriasis patients. J Clin Diag Res. 2014;8(11):CC14-CC16.

Punwani N, Scherle P, Flores R, Shi J, Liang J, Yeleswaram S, . . . Gottlieb A. Preliminary clinical activity of a topical JAK1/2 inhibitor in the treatment of psoriasis. Journal of the American Academy of Dermatology. Oct 2012;67(4):658-664.

Rachakonda TD, Schupp CW, Armstrong AW. Psoriasis prevalence among adults in the United States. Journal of the American Academy of Dermatology. Mar 2014;70(3):512-516.

Radogna F, Diederich M, Ghibelli L. Melatonin: a pleiotropic molecule regulating inflammation. Biochemical pharmacology. Dec 15 2010;80(12):1844-1852.

Reich K, Hartl C, Gambichler T, Zschocke I. Retrospective data collection of psoriasis treatment with fumaric acid esters in children and adolescents in Germany (KIDS FUTURE study). Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. Jan 2016;14(1):50-57.

Reich K. The concept of psoriasis as a systemic inflammation: implications for disease management. J Eur Acad Dermatol Venereol. 2012;26(Suppl 2):3-11.

Reiter RJ, Tan DX, Paredes SD, Fuentes-Broto L. Beneficial effects of melatonin in cardiovascular disease. Annals of medicine. May 6 2010;42(4):276-285.

Richards HL, Ray DW, Kirby B, et al. Response of the hypothalamic-pituitary-adrenal axis to psychological stress in patients with psoriasis. Br J Dermatol. 2005;153(6):1114-20.

Riyaz N, Arakkal FR. Spa therapy in dermatology. Indian journal of dermatology, venereology and leprology. Mar-Apr 2011;77(2):128-134.

Roelofzen JH, Aben KK, Oldenhof UT, Coenraads PJ, Alkemade HA, van de Kerkhof PC, . . . Kiemeney LA. No increased risk of cancer after coal tar treatment in patients with psoriasis or eczema. The Journal of investigative dermatology. Apr 2010;130(4):953-961.

Roos S, Hammes S, Ockenfels HM. [Psoriasis. Natural versus artificial balneophototherapy]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. Aug 2010;61(8):683-690.

Ryan C, Kirby B. Psoriasis is a systemic disease with multiple cardiovascular and metabolic comorbidities. Dermatol Clin. 2015;33:41-55.

Sanford M, McKeage K. Secukinumab: first global approval. Drugs. 2015;75(3):329-38.

Sankowski AJ, Lebkowska UM, Cwikla J, Walecka I, Walecki J. Psoriatic arthritis. Polish journal of radiology / Polish Medical Society of Radiology. Jan 2013;78(1):7-17.

Schalock PC. Merck Manual. Professional Version. Psoriasis. Available at: http://www.merckmanuals.com/professional/dermatologic-disorders/psoriasis-and-scaling-diseases/psoriasis#v962308. Last updated 11/2014. Accessed 12/3/2015.

Schett G, Coates LC, Ash ZR, Finzel S, Conaghan PG. Structural damage in rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis: traditional views, novel insights gained from TNF blockade, and concepts for the future. Arthritis research & therapy. 2011;13 Suppl 1:S4.

Schmitt J, Rosumeck S, Thomaschewski G, Sporbeck B, Haufe E, Nast A. Efficacy and safety of systemic treatments for moderate-to-severe psoriasis: meta-analysis of randomized controlled trials. Br J Dermatol. Feb 2014;170(2):274-303.

Sen BB, Rifaioglu EN, Ekiz O, Inan MU, Sen T, Sen N. Neutrophil to lymphocyte ratio as a measure of systemic inflammation in psoriasis. Cutaneous and ocular toxicology. Sep 2014;33(3):223-227.

Serwin AB, Wasowicz W, Gromadzinska J, et al. Selenium status in psoriasis and its relations to the duration and severity of the disease. Nutrition. 2003;19:301-304.

Shani J, Livshitz T, Robberecht H, Van Grieken R, Rubinstein N, Even-Paz Z. Increased erythrocyte glutathione peroxidase activity in psoriatics consuming high-selenium drinking water at the Dead-Sea Psoriasis Treatment Center. Pharmacological research communications. May 1985;17(5):479-488.

Sharma S, Singh H, Ahmad N, Mishra P, Tiwari A. The role of melatonin in diabetes: therapeutic implications. Arch Endocrinol Metab. Aug 28 2015.

Siegel D, Devaraj S, Mitra A, et al. Inflammation, atherosclerosis, and psoriasis. Clinic Rev Allerg Immunol. 2013;44:194-204.

Sivamani RK, Correa G, Ono Y, et al. Biological therapy of psoriasis. Indian J Dermatol. 2010;55(2):161-170.

Soleymani T, Hung T, Soung J. The role of vitamin D in psoriasis: a review. Int J Dermatol. 2015;54:383-392.

Søyland E, Heier I, Rodriguez-Gallego C, et al. Sun exposure induces rapid immunological changes in skin and peripheral blood in patients with psoriasis. Br J Dermatol. 2011;164:344-355.

Spah F. Inflammation in atherosclerosis and psoriasis: common pathogenic mechanisms and the potential for an integrated treatment approach. Br J Dermatol. 2008;159(Suppl. 2):10-17.

Steffen LM, Van Horn L, Daviglus ML, et al. A modified Mediterranean diet score is associated with a lower risk of incident metabolic syndrome over 25 years among young adults: the CARDIA (Coronary Artery Risk Development in Young Adults) study. Br J Nutr. 2014;112(10):1654-61.

Stern RS. The risk of squamous cell and basal cell cancer associated with psoralen and ultraviolet A therapy: a 30-year prospective study. J Am Acad Dermatol. 2012;66:553-62.

Stern RS. Psoralen and Ultraviolet A Light Therapy for Psoriasis. New England Journal of Medicine. 2007;357(7):682-690.

Stern RS. The risk of melanoma in association with long-term exposure to PUVA. Journal of the American Academy of Dermatology. May 2001;44(5):755-761.

Stern RS, Zierler S, Parrish JA. Skin carcinoma in patients with psoriasis treated with topical tar and artificial ultraviolet radiation. Lancet. Apr 5 1980;1(8171):732-735.

Sun J, Zhao Y, Hu J. Curcumin inhibits imiquimod-induced psoriasis-like inflammation by inhibiting IL-1 beta and IL-6 production in mice. PLoS ONE. 2013;8(6):e67078.

Surette ME. The science behind dietary omega-3 fatty acids. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne. Jan 15 2008;178(2):177-180.

Tahir R, Mujtaba G. Comparative efficacy of psoralen - UVA photochemotherapy versus narrow band UVB phototherapy in the treatment of psoriasis. Journal of the College of Physicians and Surgeons--Pakistan : JCPSP. Oct 2004;14(10):593-595.

Telfer NR, Chalmers RJ, Whale K, Colman G. The role of streptococcal infection in the initiation of guttate psoriasis. Archives of dermatology. 1992;128(1):39-42.

Thomson GT, Johnston JL, Baragar FD, Toole JW. Psoriatic arthritis and myopathy. The Journal of rheumatology. Mar 1990;17(3):395-398.

Thorleifsdottir RH, Sigurdardottir SL, Sigurgeirsson B, et al. Improvement of psoriasis after tonsillectomy is associated with a decrease in the frequency of circulating T cells that recognize streptococcal determinants and homologous skin determinants. J Immunol. 2012;188:5160-5165.

Tobin AM, Hughes R, Hand EB, et al. Homocysteine status and cardiovascular risk factors in patients with psoriasis: a case-control study. Clin Exp Dermatol. 2011;36(1):19-23.

Togni S, Maramaldi G, Di Pierro F, Biondi M. A cosmeceutical formulation based on boswellic acids for the treatment of erythematous eczema and psoriasis. Clinical, Cosmetic and Investigational Dermatology. 11/11/2014;7:321-327.

Traub M, Marshall K. Psoriasis – pathophysiology, conventional, and alternative approaches to treatment. Altern Med Rev. 2007;12(4):319-30.

UMMC. University of Maryland Medical Center. Health Information. Psoriasis. Available at: http://umm.edu/health/medical-reference-guide/complementary-and-alternative-medicine-guide/condition/psoriasis. Last updated 4/8/2014a. Accessed 8/28/2015 .

UMMC. University of Maryland Medical Center. Health Information. Complementary and Alternative Medicine Guide. Turmeric. Available at: https://umm.edu/health/medical/altmed/herb/turmeric. Last updated: 6/26/2014b. Accessed 9/10/2015.

Upala S, Sanguankeo A. Effect of lifestyle weight loss intervention on disease severity in patients with psoriasis: a systematic review and meta-analysis. Int J Obes. 2015;39:1197-1202.

Usatine RP, Marcellin L. First Consult. Psoriasis. Copyright 2013 Elsevier BV, Inc. www.clinicalkey.com. Last updated 8/29/2013. Accessed 9/18/2015.

van Schooten FJ, Godschalk R. Coal tar therapy. Is it carcinogenic? Drug safety. Dec 1996;15(6):374-377.

Verma S, Thakur BK. Dramatic response to oral zinc in a case of subacute form of generalized pustular psoriasis. Indian J Dermatol. 2012;57(4):323-324.

Vieth R, McCarten K, Norwich KH. Role of 25-hydroxyvitamin D3 dose in determining rat 1,25-dihydroxyvitamin D3 production. The American journal of physiology. May 1990;258(5 Pt 1):E780-789.

Villani AP, Rouzaud M, Sevrain M, et al. Prevalence of undiagnosed psoriatic arthritis among psoriasis patients: systematic review and meta-analysis. J Am Acad Dermatol. 2015;73:242-8.

Vitezova A, Zillikens MC, van Herpt TT, Sijbrands EJ, Hofman A, Uitterlinden AG, . . . Kiefte-de Jong JC. Vitamin D status and metabolic syndrome in the elderly: the Rotterdam Study. European journal of endocrinology / European Federation of Endocrine Societies. Mar 2015;172(3):327-335.

Wang C, Lin A. Efficacy of topical calcineurin inhibitors in psoriasis. Journal of cutaneous medicine and surgery. Jan-Feb 2014;18(1):8-14.

Wang H, Syrovets T, Kess D, Büchele B, Hainzl H, Lunov O, . . . Simmet T. Targeting NF-κB with a Natural Triterpenoid Alleviates Skin Inflammation in a Mouse Model of Psoriasis. The Journal of Immunology. October 1, 2009 2009;183(7):4755-4763.

Wang YN, Zhang Y, Wang Y, Zhu DX, Xu LQ, Fang H, Wu W. The beneficial effect of total glucosides of paeony on psoriatic arthritis links to circulating Tregs and Th1 cell function. Phytotherapy research : PTR. Mar 2014;28(3):372-381.

Whyte HJ, Baughman RD. Acute guttate psoriasis and streptococcal infection. Archives of dermatology. 1964;89(3):350-356.

Wollina U. Fumaric acid esters in dermatology. Indian Dermatology Online Journal. Jul-Dec 2011;2(2):111-119.

Wolters M. Diet and psoriasis: experimental data and clinical evidence. Br J Dermatol. 2005;153:706-714.

Wong T, Hsu L, Liao W. Phototherapy in psoriasis: a review of mechanisms of action. Journal of cutaneous medicine and surgery. Jan-Feb 2013;17(1):6-12.

Wu JJ, Nguyen TU, Poon KYT, et al. The association of psoriasis with autoimmune diseases. J Am Acad Dermatol. 2012;67:924-30.

Yeung H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ, . . . Gelfand JM. Psoriasis severity and the prevalence of major medical comorbidity: a population-based study. JAMA Dermatol. Oct 2013;149(10):1173-1179.

Yin LL, Zhang Y, Guo DM, et al. Effects of zinc on interleukins and antioxidant enzyme values in psoriasis-induced mice. Biol Trace Elem Res. 2013;155:411-415.

Yosipovitch G, Goon A, Wee J, Chan YH, Goh CL. The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis. Br J Dermatol. Nov 2000;143(5):969-973.

Zamfir Chiru AA, Popescu CR, Gheorghe DC. Melatonin and cancer. Journal of medicine and life. Sep 15 2014;7(3):373-374.

Zavorsky GS, Kubow S, Grey V, et al. An open-label dose-response study of lymphocyte glutathione levels in healthy men and women receiving pressurized whey protein isolate supplements. Int J Food Sci Nutr. 2007;58(6):429-36.

Zerilli T, Ocheretyaner E. Apremilast (Otezla): A New Oral Treatment for Adults With Psoriasis and Psoriatic Arthritis. Pharmacy and Therapeutics. 2015;40(8):495-500.