Oxidized LDL Panel Blood Test

Item # LC100034

Oxidized LDL Panel Blood Test  - Life Extension

Oxidized LDL Panel Blood Test

Item # LC100034

Oxidized low density lipoprotein (LDL) is “bad” cholesterol modified by oxidation. Myeloperoxidase (MPO) oxidizes LDL. MPO is an enzyme released by white blood cells that measures the body’s response to damage in the artery walls.

This panel contains the following tests:

  • Oxidized LDL (OxLDL) - LDL cholesterol (the “bad” cholesterol) that has been modified by oxidation, triggering inflammation leading to the formation of plaque in the arteries.
  • Myeloperoxidase (MPO) - An enzyme released by white blood cells that measures your body’s response to damage in your artery walls.

If you have normal cholesterol levels, you may assume you’re not at risk for a heart attack or stroke. But that’s not necessarily the case. Nearly 50% of all heart attacks occur in people with “normal” cholesterol levels. That’s because dangerous inflammation present in the walls of your arteries is often the primary contributor of risk, contributing to both vulnerable plaque formation and rupture. The good news is that inflammation can be easily measured to determine your inflammatory status and cardiovascular risk.

Why should you get your oxidized LDL levels tested? The facts speak for themselves:

  • Individuals with high levels of OxLDL are 4 times more likely to develop metabolic syndrome in the next five years.1
  • Increased OxLDL levels are associated with the presence of coronary artery disease2-4
  • Levels of OxLDL increase in a step-wise fashion as the severity of coronary artery disease increases.5

MPO oxidizes LDL making it atherogenic, and HDL (your good cholesterol) rendering it dysfunctional. This results in inflammation linked to plaque buildup inside the artery wall. Still not concerned that you are at risk for a heart attack? Read on …

  • Individuals with elevated MPO levels are more than twice as likely to experience cardiovascular mortality.6
  • Elevated MPO levels predict the risk of heart disease in subgroups otherwise associated with low risk.7,8
  • MPO levels are not likely to be elevated due to chronic infections or rheumatologic disorders due to the fact that MPO in the blood is a specific marker of vascular inflammation and vulnerable plaque.

Sample Report


Fasting is not required. Take all medications as prescribed.


  1. Holvoet P et al. Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA. 2008; 299: 2287-2293
  2. Holvoet P et al. Circulating oxidized LDL is a useful marker for identifying patients with coronary artery disease. Arterioscler Thromb Vasc Biol. 2001; 21: 844-848.
  3. Nishi K et al. Oxidized LDL in carotid plaques and plasma associates with plaquie instability. Aterioscler. Thromb Basc Biol. 2002; 22: 1649-1654
  4. Tsimikas S et al. Oxidized phospholipids, Lp(a) lipoprotein, and coronary artery diseae. N Engl J Med, 2005; 353: 46-57
  5. Ehara D et al. Elevated levels of oxidized low density lipoprotein show a positive relationship with the severity of acute coronary sndromes. Circulation, 2001: 103:1955-1960
  6. Heslop CL et al. Myeloperoxidase and C-reactive protein have combined utility for long-term prediction of cardiovascular mortality after coronary angiography. J AM Coli Cardiol. 2010; 55: 1102-1109
  7. Meuwese MC et al. Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: The EPIC-Norfolk prospective population study. J Am Coli Cardiol. 2007; 50: 159-165
  8. Karakas M eta al. Myeloperoxidase is associated with incident coronary heart disease independently of tradional risk factors: Results from the MONICA/KORA Augsburg study. J Intern Med. 2012; 271: 43-50

The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.

Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.

SALE: $115.25
Save 26%

Be the first to write a review

Write a Review

Oxidized LDL Panel Blood Test

  • $155.00
  • Sale $115.25
  • Save 26%

Why Life Extension?

100% Satisfaction Guarantee

Full one-year, no-hassle returns, money-back guarantee.

Highly Recommended

98% of our customers recommend us to family and friends. Life Extension is proud to be recognized as the #1 Catalog/Internet Brand 4 Time Winner.

Complimentary, Personalized Guidance

Medical doctors, nutritionists & other health professionals are passionate about providing personalized solutions to help you achieve optimal health.

Efficacious Formulas

40 years of research dedicated to bringing you premium, scientifically-validated formulations.

Product Transparency

99% of our products are manufactured in the U.S, and a Certificate of Analysis is available for every product we produce.

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer