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The information presented in Supplement Guide is for informational purposes only and should not be considered medical advice. Nutritional recommendations are based on established guidelines for people of average health and on associations between vitamins, minerals, and herbs with health conditions from published scientific studies (human, animal, or in vitro), clinical experience, or traditional usage. These associations may not be true for all individuals and are not based on specific product brands or formulations. Nutritional and herbal products may vary widely in ingredient purity, concentration, and combinations, which may affect people differently. Consult your doctor, pharmacist, or other professional for any health problem and before adding supplements to your self-care practices or discontinuing any prescribed medications. It is important not to make any changes in your self-care, including taking supplements, before or after a surgery without your doctor's express recommendation. In addition, please consult with your healthcare practitioner to make sure that your cumulative daily intake of copper, selenium, zinc, vitamin B6, folic acid, or any other nutrient, does not exceed established, tolerable upper intake levels.
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- Vitamins & Supplements
- Skin Care
Skin Care Products that Nourish Inside & Out


Look your Best with our Science-Based Skin Care Products
Our skin care products nourish your body inside and out, helping to revitalize and protect your skin from exposure. Replenish your skin with Gummy Science™ Youthful Collagen gummies and Skin Restoring Ceramides, and smooth on softness with our skin creams, lotions and serums.
3 Reasons Why Everyone Should Use Our Skin Care Products
- Helps smooth the appearance of fine lines & wrinkles
- Supports healthy skin hydration
- Promotes youthful skin elasticity & health
Our Recommendation
Compare Formulations
Our skin care products are designed to replenish your skin both from the outside and the inside. Explore our products to determine which is right for your body and budget.

Life Extension® Skin Care
Beautify and protect your skin from the inside with once-daily Skin Restoring Ceramides, Shade Factor™ capsules and the delicious cherry-flavored gummies of Gummy Science™ Youthful Collagen. Plus get whole-body softness and a smooth, healthy appearance with our creams, lotion and serum.
See Life Extension® Skin Care Products
Cosmesis Skin Care
Our Cosmesis line of cleansers, lotions, creams and serums, formulated exclusively for Life Extension, is designed to target specific areas such as face and neck to help maintain beautiful, radiant skin and reduce the appearance of wrinkles, sagging skin and other changes that come with age.
See Cosmesis Skin Care ProductsLife Extension® Skin Care
Help smooth the appearance of wrinkles and promote healthy skin hydration with our skin supplements, while restoring and protecting your skin with our topical Skin Care Collection products.
Skin Care Collection Day Cream
Daytime nourishment to regenerate collagen & moisturize
$37.50- $37.50
- Save 0%
$37.50
Support collagen regeneration, replenish moisture and support against signs of aging with the daytime nourishment in Skin Care Collection Day Cream.
Skin Care Collection Night Cream
Melatonin-based formula for nighttime skin rejuvenation
$29.25- $29.25
- Save 0%
$29.25
Support cell regeneration, replenish moisture and diminish signs of aging while you sleep with the melatonin-based Skin Care Collection Night Cream.
Skin Care Collection Anti-Aging Serum
Minimize the appearance of fine lines and wrinkles
$45.00- $45.00
- Save 0%
$45.00
Support cell regeneration, replenish moisture and minimize the appearance of fine lines and wrinkles with the science-based botanicals and ceramides in the Skin Care Collection Anti-Aging Serum.
Cosmesis Skin Care
Restore your skin’s healthy, beautiful glow and diminish the signs of aging with the powerful serums and creams of our Cosmesis Collection.
$34.50- $20.70
- Save 40%
$20.70
Using 6 compounds found in nature, including n-acetyl glucosamine and macadamia oil, Advanced Peptide Hand Therapy helps to rejuvenate and rehydrate damaged skin.
Ultimate MicroDermabrasion
MicroDermabrasion exfoliant revitalizes dull skin
$29.25- $17.55
- Save 40%
$17.55
This MicroDermabrasion exfoliant combines different ingredients with properties to refresh and restore the look and feel of your skin.
Advanced Under Eye Serum with Stem Cells
Fights effects of time & exposure
$36.75- $22.05
- Save 40%
$22.05
Stem cell eye serum made from a species of Swiss apple that’s clinically studied to fight the effects of time and exposure for the delicate under-eye skin, reducing the appearance of wrinkles by 15% after just one month of use.
$44.25- $26.55
- Save 40%
$26.55
Using the strength of herbal ingredients like peptides and plant stem cells, our eyelash booster promotes growth and thickness.
$44.25- $26.55
- Save 40%
$26.55
Our Collagen Boosting Peptide Serum has a high concentration of snow algae that helps boost both hydration and collagen production in skin cells and peptides, helping skin stay smooth and youthful-looking.
$34.50- $17.25
- Save 50%
$17.25
This innovative formula combines the protective properties of resveratrol with tea polyphenols in one antioxidant serum to protect and preserve your skin.
$36.75- $18.37
- Save 50%
$18.37
Collagen is essential for skin firmness, cohesion, and resilience. This formula was developed with three powerful peptides that renew all major collagen types—promoting youthful looking skin.
$63.75- $29.25
- Save 54%
$29.25
This face serum combines clinically studied antioxidant tea extracts with a 12% vitamin C concentration to promote smoother, hydrated skin and a healthy, even skin tone.
$29.25- $17.55
- Save 40%
$17.55
Formulated with ingredients that help stimulate collagen synthesis and help inhibit elastin breakdown, Cosmesis’ Tightening & Firming Neck Cream protects and strengthens the delicate décolleté area.
$44.25- $13.27
- Save 70%
$13.27
Helps brighten skin, diminish the appearance of age spots and equalize skin tone with a blend of scientifically studied compounds that inhibit melanin output and moisturize the skin.
$29.00- $17.40
- Save 40%
$17.40
Three innovative vitamin A compounds reduce the appearance of fine lines and wrinkles, balance skin pigmentation and encourage more vibrant, youthful-looking skin.
$48.75- $29.25
- Save 40%
$29.25
Help moisturize skin and promote the body’s production of collagen and elastin with the powerful, highly active coffee compounds in our Anti-Aging Rejuvenating Face Cream.
Advanced Triple Peptide Serum
Reduce the appearance of wrinkles with collagen peptides
$48.75- $29.25
- Save 40%
$29.25
Reduce the appearance of wrinkles, soften and smooth skin and support collagen renewal with the powerful peptides that make up Advanced Triple Peptide Serum.
$55.50- $27.75
- Save 50%
$27.75
Based on stem cells from a rare Swiss apple, this serum helps protect and preserve youthful looking skin.
$34.50- $20.70
- Save 40%
$20.70
Formulated around the plant extract from the argan tree, this scalp serum helps refresh and rejuvenate your hair. With argan oil and supporting compounds, this formula helps revive dull, brittle hair.
$28.50- $17.10
- Save 40%
$17.10
Cosmesis’ Cucumber Hydra Peptide Eye Cream supports the skin around the eyes with essential peptides to promote smoothing and protect normal aging skin.
$52.13- $26.06
- Save 50%
$26.06
Use antioxidants like vitamin E and tea extracts to revitalize your skin. The powerful anti-aging nutrients in this face cream help quench free radicals and restore healthy, youthful-looking skin.
$44.25- $26.55
- Save 40%
$26.55
Cosmesis’ Eye Lift Cream uses plant extracts to help lift and firm around the eyes to support hydrated skin for a youthful look and feel.
$49.50- $24.75
- Save 50%
$24.75
Our stem cell cream takes the protective, regenerative properties of stem cells from the Alpine rose to help guard your skin from the everyday dangers of the environment.
$18.00- $10.80
- Save 40%
$10.80
This formula combines the lip rejuvenating power of vitamin C with other nutrients to help keep your lips moisturized, youthful-looking and healthy.
$44.25- $26.55
- Save 40%
$26.55
Harnessing the power of plant stem cell extracts and acetyl tetrapeptide inside Multi Stem Cell Skin Tightening Complex, it provides key ingredients to help improve the firmness and texture of normally aging skin.
$55.88- $27.94
- Save 49%
$27.94
Intensive morning and night cream minimizes the appearance of under-eye puffiness and darkness and softens the appearance of skin affected by repeated environmental exposure.
$33.75- $19.99
- Save 40%
$19.99
Ultimate Telomere Cream uses astragalus root extract to help revitalize aging skin. By restoring activity of an enzyme called telomerase, this cream enhances skin cell longevity right down to your DNA.
$43.50- $26.10
- Save 40%
$26.10
Using the hydrating power of hyaluronic acid, Hyaluronic Facial Moisturizer provides hydration and protection for all skin types. Even dry, delicate and aging skin will benefit from softer-looking skin.
$36.75- $22.05
- Save 40%
$22.05
Our peptide serum combines sea fennel and date palm extracts with clinically researched growth factors to support natural skin pathways and diminish signs of aging.
$55.88- $27.94
- Save 49%
$27.94
Harnessing the power of soy and rice peptides, plus hyaluronic acid and seaweed extract, this under-eye serum works to help keep skin looking smooth and firm.
$44.25- $26.55
- Save 40%
$26.55
Formulated with extracts that have nourishing ad restorative properties, this formula helps smooth the appearance of fine lines and wrinkles to support more vibrant, youthful-looking skin.
$28.50- $17.10
- Save 40%
$17.10
Cosmesis’ Melatonin Advanced Peptide Cream powerfully combines melatonin, peptides and a coconut amino acid complex to promote healthy and youthful looking skin.
$36.75- $22.05
- Save 40%
$22.05
This exfoliating scrub gently removes dead skin cells and oil buildup with amber crystals, leaving behind smoother, softer skin.
$39.75- $23.85
- Save 40%
$23.85
Our Skin Firming Complex is a multi-nutrient serum that lifts and tightens skin on the face and neck areas for visibly firm, defined, youthful-looking skin.
$44.25- $26.55
- Save 40%
$26.55
This hypoallergenic foaming facial cleanser gently washes away dirt, leaving behind refreshed skin. It is suitable for all skin types, even dry and sensitive skin.
$29.96- $17.97
- Save 40%
$17.97
This hydrating facial mist rejuvenates the skin with the help of Aqualance™ to aid in the fight against skin dehydration and help sustain smooth, soft and bright skin.
$48.75- $29.25
- Save 40%
$29.25
Cosmesis’ Advanced Growth Factor Serum utilizes four essential growth factors to promote healthy skin rejuvenation and support firm and youthful looking skin.
Advanced Probiotic-Fermented Eye Serum
Promotes probiotic balance around the eyes and skin
$29.25- $11.70
- Save 60%
$11.70
$48.75- $29.25
- Save 40%
$29.25
Specifically designed for the delicate skin around the eye, our Renewing Eye Cream combines several complementary compounds that, due to their beautifying effects, are generating interest among dermatologists.
$39.75- $23.85
- Save 40%
$23.85
Advanced Peptide Anti-Oxidant Serum combines clinically studied ingredients including peptides and fruit extracts to support firm, youthful skin.
$39.75- $23.85
- Save 40%
$23.85
All-Purpose Soothing Relief Cream brings together powerful skin protectors in arnica cream, oats and vitamins D and K to help revitalize and moisturize the skin.
$27.00- $27.00
- Save 0%
$27.00
This innovative vitamin D lotion combines the power of antioxidants with skin-nourishing vitamin D3 to instantly moisturize dry, rough skin and enhance natural appearance.
$55.88- $27.94
- Save 49%
$27.94
Lift, tighten and smooth the skin on your face, neck and chest with hyaluronic acid and a concentrated antioxidant tea blend in Cosmesis’ best skin tightening cream for face and neck.
$48.00- $28.80
- Save 40%
$28.80
Keep your neck looking beautiful! This antioxidant-rich topical neck cream uses potent vitamins, tea extracts and more to counteract the visible effects of aging.
Hyaluronic Oil Free Facial Moisturizer
Oil-free facial moisturization at your fingertips
$43.50- $26.10
- Save 40%
$26.10
Based on clinical testing, this formula is designed with your needs in mind. Using potent tea extracts, this light, oil-free facial moisturizer helps keep oily skin hydrated and protected, worry-free.
$29.25- $8.77
- Save 70%
$8.77
Designed to help limit oil buildup and support exfoliation, our Purifying Facial Mask helps inhibit the frequency of blemishes using zinc oxide, sulfur and camphor.
$36.75- $22.05
- Save 40%
$22.05
This cutting-edge formula uses caprylic acid & clinically studied teprenone to help maintain the glow of youth with the benefits of this rejuvenating skin cream.
$67.46- $33.73
- Save 50%
$33.73
Cosmesis’ Ultra Wrinkle Relaxer anti-wrinkle serum blends a hexapeptide and concentrated antioxidant tea extracts to lessen the appearance of wrinkles and promote the appearance of smooth skin.
$48.75- $29.25
- Save 40%
$29.25
Uneven skin color and age spots can make skin look old beyond its years. Our lightening cream minimizes this age-related effect and helps rejuvenate skin tone and reduce the appearance of dark spots to promote youthful, radiant skin.
Vitamin K Cream
Minimize the appearance of blood vessels & bruises with vitamin K cream
$59.63- $59.63
- Save 0%
$59.63
On its own, vitamin K is a powerful ingredient used to minimize topical discolorations like redness, blotches or bruises. This vitamin K cream combines with topical arnica to maximize its effects.
$54.00- $54.00
- Save 0%
$54.00
This anti-aging mask uses the power of hyaluronic acid and potent antioxidant tea extracts to fight the appearance of aging, to restore youthful radiance and to promote smoother, healthy-looking skin.
$44.25- $26.55
- Save 40%
$26.55
Vitamin C has been shown to help reduce the appearance of wrinkles, fine lines and age spots. Our Triple Action Vitamin C Cream helps replenish this important vitamin.
$44.25- $44.25
- Save 0%
$44.25
Cosmesis’ Environmental Support Serum helps promote long lasting and healthy skin support against the free radical damage from environmental factors.
Related Products
$45.00- $45.00
- Save 0%
$45.00
Our Once-Daily Health Booster delivers the health benefits of essential fat-soluble vitamins and nutrients from plant extracts and a phospholipid blend for eye health, all contained in one convenient softgel.
Mitochondrial Energy Optimizer with PQQ
PQQ benefits the body by energizing every cell
$51.00- $51.00
- Save 0%
$51.00
PQQ’s benefits stem from our special formula, which is designed to promote healthy mitochondria, the cellular structures that produce energy needed by the entire body.
Super Omega-3 EPA/DHA Fish Oil, Sesame Lignans & Olive Extract
Comprehensive fish oil benefits for heart health, brain & beyond
$24.00- $24.00
- Save 0%
$24.00
Our best-selling Super Omega-3 EPA/DHA formula is an IFOS™ 5-star certified fish oil packed with EPA and DHA fatty acids, olive polyphenols and more to promote heart health, brain health, and beyond.
MacuGuard® Ocular Support with Saffron & Astaxanthin
Complete support for eye health & night vision
$33.00- $33.00
- Save 0%
$33.00
Nutrients like lutein and astaxanthin benefit eye health. Our MacuGuard® formula delivers these nutrients, plus zeaxanthin, meso-zeaxanthin, saffron and more for comprehensive eye health support.
Super Omega-3 Plus EPA/DHA Fish Oil, Sesame Lignans, Olive Extract, Krill & Astaxanthin
Omega-3 formula with EPA & DHA benefits for brain & heart health
$33.75- $33.75
- Save 0%
$33.75
Much more than a fish oil supplement, this formula includes omega-3 EPA/DHA benefits, plus sesame lignans, olive extract, krill and astaxanthin for a more comprehensive approach to heart and cognitive health.
Advanced Curcumin Elite™ Turmeric Extract, Ginger & Turmerones
Highly absorbable curcumin with complementary plant extracts
$20.00- $20.00
- Save 0%
$20.00
We’ve augmented our ultra-bioavailable Curcumin Elite™ curcumin-fenugreek combo with complementary ginger and turmerone extracts to create our Best in Class curcumin formula.
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