Methylmalonic Acid Blood Test

Item # LC706961

Methylmalonic Acid Blood Test

Item # LC706961

Increased Methylmalonic acid (MMA) levels are often associated with early stages of B12 deficiency. A MMA blood test may be ordered along with a homocysteine test when a vitamin B12 deficiency is suspected.

Vitamin B12 is necessary for red blood cell production from bone marrow. When B12 levels are low, red blood cell production decreases, resulting in anemia. As B12 status declines, B12-dependent enzymes no longer function properly and normal metabolism is consequently impaired, leading to a build-up of methylmalonic acid (MMA). Age-stratified serum MMA values have been observed to be consistent with the prevalence of Vitamin B12 deficiency in the elderly population.1

  1. https://pubmed.ncbi.nlm.nih.gov/20599863/

Note

Blood testing is the preferred and most common way to measure MMA, However, early morning-urine testing offers a convenient at-home method of testing MMA status. The easiest option to obtain an early morning MMA urine measurement is with the at-home B12 Functional Status test, LC100099.

Instructions

Fasting is not required for this test. Take all medications as prescribed.

The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.

Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.

A clinician's order is required for many tests. Where applicable, an independent clinician will review your test request and determine whether to authorize the test, if appropriate. For additional information, see PWNHealth Terms of Service.

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Methylmalonic Acid Blood Test

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