Life Extension Magazine®

Example of nasal passages that can be affected by sinus problems

Fungal Infections and Sinus Problems

While environmental toxins and antibiotics contribute to chronic sinusitis, experts say fungal infections are an underdiagnosed cause of this condition. Research shows that a patented, natural, antimicrobial intranasal solution delivers substantial relief.

Scientifically reviewed by: Dr. Vanessa Pavey, ND, in August 2023. Written by: Patrick Quillin, PhD, RD, CNS.

Fungal infections can cause a troublesome array of health problems ranging from daily lethargy and sinusitis to life-threatening infections. However, the role of fungal infections in sinusitis is underestimated.

A study from the Mayo Clinic showed positive fungal cultures in those with chronic sinusitis.1 Subjects in a separate study using a patented natural antimicrobial intranasal solution found substantial relief from sinusitis.2

People who suffer from chronic sinus problems may find a renewed sense of vitality once their sinus problems are cleared through the use of this nontoxic antimicrobial solution.

Cause of Many Illnesses

Cause of Many Illnesses  

Many smart people in the global health care community argue that fungal infections are drastically underdiagnosed.

Orian Truss, MD, in his seminal work The Missing Diagnosis, argued that fungal infections may be at the root of many refractory ailments like stress, fatigue, depression, pain, and especially autoimmune conditions.

A.V. Costantini, MD, former director of the World Health Organization Mycotoxin Collaborating Center at the University of Freiburg, Germany, has written a series of books on fungal bionics claiming that many degenerative diseases of mankind are caused by fungal mycotoxins in the body (from the fungus organism) or fungal mycotoxins in our food supply through moldy grains and other contamination.3

While certain individuals are at a higher risk for fungal infections,4,5 some researchers discuss the connection between mycotoxins and their role in cancer. Many byproducts of fungi, or mycotoxins, can cause cancer. 6 Aflatoxins, a byproduct found in moldy grains and other foods, is one of the most carcinogenic substances ever studied.7 Fungi can produce biofilms, which are best compared to a “bulletproof shield” against drugs because the biofilm makes the fungi resistant to the strongest antifungal drugs in use.8 With the explosion in research on the human microbiota (trillions of cells in the gut that dramatically affect health), scientists are finding that fungi probably play a role in many human health problems including sinusitis.

Sinusitis: More than a Minor Annoyance

Chronic sinusitis is one of the more commonly reported reasons for patient visits to a family physician. Each year, about 31 million Americans report having sinusitis, involving 73 million restricted activity days per year at a cost of $5.8 billion in medical expenses. Common treatments for sinusitis involve antibiotics, steroid nasal sprays, prescription antihistamines, and eventually 200,000 sinus surgeries per year at a cost of $800 million.2,9,10

Masters of Evasion

Fungi are the top and the bottom of the food chain. They make potent medicines (think antibiotics) and perilous poisons. Through their bewildering array of digestive enzymes, they can decompose any life form back to the earth. Without fungi, the earth would be shoulder deep in dead matter that did not decay.

Fungi, mushrooms, yeast, and mold are all part of the kingdom Fungi or Mycota. While there are about 300 different horse breeds on earth and 2,600 different species of palm trees, there are up to 5 million species of fungi with almost 300 of those species causing diseases in humans.11,12

Function of the Sinuses

We take in air usually through the nose, somewhere around 11,000 liters per day (equaling 388 cubic feet). This air needs to be filtered and warmed by the four pairs of sinus cavities (frontal, ethmoid, sphenoid, and maxillary). In the presence of sinusitis, there is a need to address the underlying problem by cleansing the sinus cavities with safe antimicrobial agents that work in synergism.

Method to Lower Mold Load in the Sinuses

In response to this pervasive problem, researchers developed a patented nasal solution. Clinical tests showed favorable action in people suffering from chronic sinusitis.

This nasal solution was clinically tested under the guidance of an institutional review board (IRB) at the world famous Riordan Clinic in Wichita, Kansas. Forty patients with chronic sinusitis were recruited for this study, which compared saline (salt water) solution, the preferred method of cleansing the sinuses for many ear, nose, and throat (ENT) doctors, to the antimicrobial sinus solution. In only four weeks, the antimicrobial nasal solution improved symptoms by 27%.2

About one-third of the study subjects were able to reduce their use of antibiotics and other medications while continuing with their antimicrobial nasal irrigation. The authors of this article concluded: Given the high incidence and morbidity of sinusitis, nasal irrigation seems underutilized by family physicians and otolaryngologists.”

Antibiotics are toxic yet useful substances for treating certain infections. Yet, antibiotic usage has been linked to a higher incidence of breast cancer.13 By using a safe, enriched nasal solution, the sinus sufferer may be able to reduce their intake of antibiotics, hence improving overall health.

What You Need to Know
Fight Fungal and Sinus Infections

Fight Fungal and Sinus Infections

  • Fungal infections cause a variety of health issues ranging from everyday lethargy and sinusitis to life-threatening infections.
  • A Mayo Clinic study showed positive fungal cultures in those with chronic sinusitis.
  • When treating sinusitis, it’s necessary to address the underlying problem by cleansing the sinus cavities with safe antimicrobial agents.
  • In studies, an antimicrobial nasal solution of Baptisia tinctoria, grapefruit seed extract, oregano, and nano silver, in a pH balanced isotonic blend improved symptoms by 27%.

Natural Components of Antimicrobial Nasal Irrigator

The antimicrobial nasal solution consists of four primary ingredients blended in homeopathic dosages and technique: Baptisia tinctoria (wild indigo), grapefruit seed extract, oregano, and nano silver, in a pH balanced isotonic blend.

This enriched nasal solution is intended to be used only once daily.

Simple Solution for Many Complex Health Problems

People with sinusitis, apnea (stop breathing while sleeping), halitosis (bad breath), wheezing, seasonal allergies, who snore, who work around mold (like animal dung) or sawdust (which irritates the sinuses), or who fly on commercial airlines (where you share the air with 200 people, some of whom are not well) should consider using this enriched nasal solution as a means to cleanse the sinuses, lower fungal load, and raise overall wellness level.14


People with sinus infections, as well as those with sleep apnea, who fly often, work around irritants, or suffer seasonal allergies often have a variety of health issues, from lethargy to life-threatening infections. Many sufferers test positive for fungal cultures.

While many over-the-counter solutions have a shelf life of two years maximum due to the growth of fungi in a liquid medium, this enriched sinus solution has proven to provide a five-year shelf life via stabilization studies conducted by an FDA-approved laboratory. All of the ingredients in this sinus solution work synergistically to retard the growth of fungi as proven by its extraordinary shelf life.

Those with sinus issues should consider cleansing the sinus cavities with antimicrobial agents. A pH-balanced isotonic blend solution of Baptisia tinctoria, grapefruit seed extract, oregano, and nano silver was shown to improve sinusitis symptoms by 27%.

If you have any questions on the scientific content of this article, please call a Life Extension® Wellness Specialist at 1-866-864-3027.

Patrick Quillin earned bachelor’s, master’s, and doctoral degrees in nutrition. He is a registered dietitian (RD) and certified nutrition specialist (CNS). His 17 health books, including the international bestseller Beating Cancer with Nutrition, have sold over 2 million total copies. He taught college nutrition for eight years, worked with both the La Costa Spa and Scripps Clinic, was vice president of nutrition for Cancer Treatment Centers of America for 10 years, and was a grant reviewer for the National Institutes of Health Office of Alternative Medicine and the US Army Breast Cancer Project. He has been interviewed over 200 times on radio, 40 times on TV, and has been a keynote speaker at many professional conferences. He holds two patents and is currently CEO of the publishing company Nutrition Times Press, Inc.


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