CoQ10 also has powerful antioxidant properties, protecting cell membranes, important proteins and mitochondrial DNA from oxidative stress.^7,8 Unfortunately, CoQ10 levels in the body decrease over time.^9,10

Improved bioavailability: ubiquinol

The traditional ubiquinone form of CoQ10 is difficult for the body to absorb.¹¹ That's why Life Extension® offers a highly bioavailable form of ubiquinol CoQ10 in a patented delivery system shown to absorb better than ubiquinone.^12,13 In people taking this form of ubiquinol, high levels of plasma CoQ10 were achieved in only four weeks.¹⁴

Shilajit enhances CoQ10 effectiveness

Shilajit is a nutrient discovered in the Himalayas. In preclinical models, shilajit has been shown to promote mitochondrial energy production and increase adenosine triphosphate (ATP), which is the main source of cellular energy.^15,16 The combination of CoQ10 and shilajit produced a 56% increase in cellular energy production in the brain—45% better than CoQ10 alone. Muscle tissue saw a 144% increase in ATP, more than 50% better than with CoQ10 by itself.¹⁵

CoQ10 and aging

With increasing age, in addition to declining CoQ10 levels, the body’s ability to convert ubiquinone into active ubiquinol declines.¹⁷ In a pre-clinical model, ubiquinol was up to 40% more effective at slowing measurements of aging compared with ubiquinone.¹⁸ 

PQQ promotes growth of new mitochondria

PQQ (pyrroloquinoline quinone) is a nutrient that promotes the production of new mitochondria. In fact, PQQ promotes youthful cellular function in three distinct ways:

• Promotes mitochondrial biogenesis. PQQ activates genes that promote the formation of fresh mitochondria. It also beneficially interacts with genes directly involved in mitochondrial health.¹⁹
• Mitochondrial support. PQQ’s antioxidant potency and favorable gene-expression profile act to support mitochondrial defense.²⁰
• Antioxidant power. PQQ is a potent antioxidant, and its molecular stability enables PQQ to facilitate thousands of antioxidant reactions in the mitochondria, without breaking down, for maximum antioxidant and bioenergetic support.²¹