Best In Class

Immune Senescence Protection Formula™

Standardized Cistanche • Reishi • Pu-erh Tea

  • 60 vegetarian tablets
  • Item # 02005
Best In Class

Immune Senescence Protection Formula™

Standardized Cistanche • Reishi • Pu-erh Tea

  • 60 vegetarian tablets
  • Item # 02005

Comprehensive immune system support

Our best-in-class immune system support formula goes way beyond vitamin C with standardized cistanche, reishi mushroom and pu-erh tea extracts to support immune cell health, response and ratio.
Non-GMO Vegetarian

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$0.48 / count | 30 Day Supply

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I buy it often. I use this product every day.


Love this. Keeps my immune system strong.

Debbie, AZ

We have used this product since we first began with LE.

Jill, IN

Have been taking this for years. This supports my immune system.

Dugo, AZ

Frequently Bought Together

  • This Item: Immune Senescence Protection Formula™, 60 vegetarian tablets
  • NK Cell Activator™, 30 vegetarian tablets

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Sale $48.40
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Immune Senescence Protection Formula™

Standardized Cistanche • Reishi • Pu-erh Tea

60 vegetarian tablets


$0.48/count | 30 Day Supply

Think of your immune cells as bouncers at a night club. They control who gets in, who gets kicked out and who can’t enter ever again. But over time, our immune system begins to decline, a process called immune senescence. This makes it harder for immune cells to do their job. So we developed an innovative formula to help combat immune senescence.

Immune cells are like security guards. They say who’s in, who’s out and who’s banned. However, our immune system declines over time.

Immune Senescence Protection Formula™ Benefits

  • Inhibits immune senescence by supporting an already-healthy ratio of naïve-to-memory T cells
  • Promotes youthful immune response by stimulating immune cell development & activity
  • Encourages the body’s first line of defense by promoting natural killer (NK) cell response
  • Supports bone marrow health & longevity

What is pu-erh tea?

Pu-erh tea is made from the same plant as black and green tea and is rich in polyphenols and other bioactive molecules that support immune health.

Why did we add reishi mushroom extract?

Reishi mushroom contains compounds that boost immune cell function and other immune factors that serve as your body’s first line of defense.

Know your immune cells

The three ingredients in this formula focus on encouraging the healthy function of three types of immune cells: naïve T cells, memory T cells and natural killer (NK) cells. Naïve T cells attack new invaders. Memory T cells attack previously known invaders. And NK cells function as your body’s first responders. Cistanche, reishi mushroom and pu-erh tea extracts support them in different ways.

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This formula focuses on supporting three types of immune cells: naïve T cells, memory T cells and natural killer (NK) cells. Naïve T cells attack new invaders.1 Memory T cells attack previously-known invaders.2 And NK cells function as your body’s first responders.3

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
  1. Immunol Rev.2018;285(1):218-232.
  2. Immunity. 2018;48(2):214-226.
  3. Front Immunol.2018;9:1869-1869.
  4. Inflamm Regen.2018;38:24-24.
  5. Evid Based Complement Alternat Med. 2014;2014:601383-601383.
  6. Aging Dis.2017;8(6):740-759.
  7. Anti-Aging Medicine. 2011;8(2):7-14.
  8. Tumor Biology. 2016;37(3):2789-2804.
  9. Int J Med Mushrooms.2011;13(5):441-448.
  10. Am J Chin Med.2011;39(01):15-27.
  11. Food Chem.2012;135(4):2222-2228.

Serving Size 2 vegetarian tablets

Servings Per Container 30

Amount Per Serving

Calcium (as calcium carbonate)

175 mg

Reishi mushroom extract (fruit body) [std. to 13.5% polysaccharides, 6% triterpenes]

980 mg

Pu-erh tea extract (leaf) [providing polyphenols, theabrownin]

650 mg

Cistanche tubulosa extract (stem and leaf) [std. to 22% echinacosides]

210 mg

Shell-broken reishi mushroom (spore)

150 mg

Other ingredients: microcrystalline cellulose, starch, croscarmellose sodium, stearic acid, aqueous film coating (hypromellose, glycerin, purified water), hydroxypropyl cellulose, maltodextrin, silica, vegetable stearate.


Dosage and Use
  • Take two (2) tablets daily with food, or as recommended by a healthcare practitioner.
  • Each serving contains approximately 32.5 mg of caffeine (the amount found in about a 3/4 cup brewed green tea).
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Actual Size

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Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer.

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