Pro-Resolving Mediators

  • 30 softgels
  • Item # 02223

Pro-Resolving Mediators

  • 30 softgels
  • Item # 02223

Helps maintain a healthy post-inflammatory response for whole-body health

This formula uses SPM precursors derived from marine oil to support healthy tissue rejuvenation, promote the natural clearing of cellular debris and help maintain a healthy balance of cytokine compounds.

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$0.70/count | 30 Day Supply

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  • This Item: Pro-Resolving Mediators, 30 softgels
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Pro-Resolving Mediators, 30 softgels - Life Extension
Senolytic Activator, 24 capsules - Life Extension

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Pro-Resolving Mediators

30 softgels


$0.70/count | 30 Day Supply

Feel like your old self again. Pro-Resolving Mediators promote a healthy post-inflammatory response—one that supports whole body health at the cellular level. These novel compounds foster an environment where new, healthy tissue can flourish, encourage your system to “clean up” cellular debris and help to maintain the vital balance between cytokine compounds.

Encouraging your body’s post-inflammatory response goes a long way toward maintaining whole-body health, starting at the cellular level.

Pro-Resolving Mediators Benefits

  • Encourages healthy tissue rejuvenation to help you feel like your old self again
  • Promotes the pathways that clear cellular debris, which allows healthy cells to flourish
  • Helps maintain the balance between cytokine compounds that your body needs to function harmoniously
  • Is the perfect complement to Curcumin Elite™, which promotes a healthy inflammatory response

An Incredible Nutrient Derived From Marine Oil

The body creates specialized pro-resolving mediators from fatty acids such as EPA and DHA omega-3s. But fish oil is not completely converted to SPMs, so you may not get the optimal health benefit from taking a fish oil alone. In fact, research indicates that SPMs and SPM precursors (such as 17-HDHA and 18-HEPE in this formula) are actually better for promoting a healthy post-inflammatory response.

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A whole-body health regimen should include nutrients that help inhibit inflammation to support whole-body health, as well as those that help maintain the body’s healthy post-inflammatory response.1 The SPM compounds in this innovative supplement do just that: promote a healthy post-inflammatory response.

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These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
  1. Semin Immunol. 2018;40:36-48.
  2. J Surg Res. 2019;238:164-174.
  3. Diabetes. 2013;62(6):1945-56.
  4. Am J Clin Nutr. 2015;102(6):1357-64.
  5. 2014;211(8):1673-1687.
  6. Front Immunol. 2019;10:307.
  7. JCI Insight. 2018;3(6)
  8. Sci Rep. 2018;8(1):11873.
  9. Mol Aspects Med. 2017;58:1-11.
  10. Atherosclerosis. 2016;250:158-65.

Serving Size 1 softgels

Amount Per Serving



Total Fat

0.5 g


<5 mg

Marine Lipid Concentrate

500 mg

[providing 300 mcg of Pro-Resolving Mediators including 18-hydroxyeicosapentaenoic acid (18-HEPE), 17-hydroxydocosahexaenoic acid (17-HDHA), & 14-hydroxydocosahexaenoic acid (14-HDHA)]


Other ingredients: highly refined marine oil concentrate, (squid, anchovy, sardine, herring, mackerel), gelatin, olive oil, glycerin, purified water, lemon flavor, mixed tocopherols.



Dosage and Use
  • Take one (1) softgel daily, or as recommended by a healthcare practitioner.
  • Store tightly closed in a cool, dry place.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

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