Pro-Resolving Mediators

  • 30 softgels
  • Item # 02223

Pro-Resolving Mediators

  • 30 softgels
  • Item # 02223

Helps maintain a healthy post-inflammatory response for whole-body health

This formula uses SPM precursors from marine oil to promote the natural clearing of cellular debris, help maintain a healthy balance of cytokine compounds, and support healthy tissue rejuvenation.

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$0.70/count | 30 Day Supply

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  • This Item: Pro-Resolving Mediators, 30 softgels
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Pro-Resolving Mediators, 30 softgels - Life Extension
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Pro-Resolving Mediators

30 softgels


$0.70/count | 30 Day Supply

Specialized pro-resolving mediators (SPMs) help maintain the body’s healthy post-inflammatory response to support whole-body health. These powerful compounds promote the natural clearing of cellular debris, help maintain a healthy balance of cytokine compounds, and support healthy tissue rejuvenation.

Encouraging your body’s post-inflammatory response goes a long way toward maintaining whole-body health.

Pro-Resolving Mediators Benefits

  • Helps maintain the body’s healthy post-inflammatory response
  • Supports the body’s natural process for clearing cellular debris
  • Helps maintain healthy cytokine balance & supports healthy tissue rejuvenation
  • Contains highly purified SPM precursors derived from marine oil
  • Works best when taken in conjunction with formulas like Curcumin Elite™

An Incredible Nutrient Derived From Marine Oil

The body creates specialized pro-resolving mediators from fatty acids such as EPA and DHA omega-3s. But fish oil is not completely converted to SPMs, so you may not get the optimal health benefit from taking a fish oil alone. In fact, research indicates that SPMs and SPM precursors (such as 17-HDHA and 18-HEPE in this formula) are actually better for promoting a healthy post-inflammatory response.

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A healthy dietary regimen should include nutrients that promote a healthy inflammatory response, as well as those that help maintain a healthy post-inflammatory response.1 Pro-Resolving Mediators do just that: promote a healthy post-inflammatory response, which in turn supports whole-body health.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
  1. Semin Immunol. 2018;40:36-48.
  2. J Surg Res. 2019;238:164-174.
  3. Diabetes. 2013;62(6):1945-56.
  4. Am J Clin Nutr. 2015;102(6):1357-64.
  5. 2014;211(8):1673-1687.
  6. Front Immunol. 2019;10:307.
  7. JCI Insight. 2018;3(6)
  8. Sci Rep. 2018;8(1):11873.
  9. Mol Aspects Med. 2017;58:1-11.
  10. Atherosclerosis. 2016;250:158-65.

Serving Size 1 softgels

Amount Per Serving



Total Fat

0.5 g


<5 mg

Marine Lipid Concentrate

500 mg

[providing 300 mcg of Pro-Resolving Mediators including 18-hydroxyeicosapentaenoic acid (18-HEPE), 17-hydroxydocosahexaenoic acid (17-HDHA), & 14-hydroxydocosahexaenoic acid (14-HDHA)]


Other ingredients: highly refined marine oil concentrate, (squid, anchovy, sardine, herring, mackerel), gelatin, olive oil, glycerin, purified water, lemon flavor, mixed tocopherols.



Dosage and Use
  • Take one (1) softgel daily, or as recommended by a healthcare practitioner.
  • Store tightly closed in a cool, dry place.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Actual Size

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