PectaClear™ Detox Formula is designed to:

• Promote removal of toxins without depleting essential minerals.
• Function systemically and intestinally
• Bind toxins to inhibit re-absorption

Polyuronide Chemistry
Polyuronides, such as pectin and alginates, are naturally occurring complex polysaccharides. Citrus pectin is a soluble dietary fiber composed predominately of repeating galacturonic acid units. Alginate, found in seaweed, is made of linear chains of mannuronic (M) and guluronic (G) acid. The structure and charge of these compounds make them superior toxic metal chelators.

Metal Chelation Properties
The toxic metal binding properties of polyuronides is dependent on their degree of esterification and the type and pattern of the molecules that comprise the pectin or alginate chains. The highest binding affinities are found in pectins with a low degree of esterification and alginates that are rich in guluronic acid blocks.¹

Metal Complex Formation
Polyuronides form stacks in solution in what is known as an "egg box" structure². Each pocket of the "egg carton" contains a positively charged ion to balance the negatively charged chains. Normally the positive ions are sodium and potassium. However, toxic metals especially lead, mercury, cadmium, and radioactive metals have a higher affinity for polyuronides than the essential ions like calcium, magnesium, and potassium.^1,3 Toxic metal ions become trapped in the "egg box" structure and are eliminated from the body. USDA-ARS scientist attributed the 10% rhamnogalacturonan II content in PectaClear to the selective binding to these toxic metals.⁴

PectaClear™ Detox Formula
PectaClear™ is a carefully designed blend of modified citrus pectin (MCP) and modified alginates formulated by Isaac Eliaz, MD for optimal toxic metal chelation. The use of alginates and pectates for metal chelation is protected by US patents #6,462,029 and #7,026,302. PCC is an integral part of Dr. Eliaz's detoxification protocols. The modified citrus pectin component works systemically in the circulatory system and the alginates work predominantly in the gastrointestinal tract to inhibit re-absorption of toxins.

Clinical Studies
PectaSol-C® Modified Citrus Pectin's ability to support the removal of toxic metals from the body via the urinary tract was validated in a short term pilot study. Oral administration of PectaSol-C® Modified Citrus Pectin to healthy humans resulted in significant increases in the urinary excretion of lead, arsenic, cadmium, and mercury.⁴ The results of this clinical trails were published in collaboration with the USDA in the peer reviewed journal, Phytotherapy Research.⁵ The study shows that PectaSol-C® safely and effectively chelates lead, mercury, arsenic and other toxic metals out of the human body, and without affecting the essential minerals in the body.

A clinical trial to investigate the ability of PectaSol-C® Modified Citrus Pectin to decrease mercury burden as measured by DMPS (2,3-dimercapto-1-propanesulfonic acid) challenge, showed a significant reduction in mercury levels after five to ten months of oral administration of PectaSol-C® Modified Citrus Pectin.^6,7 A recent study reported that PectaClear significantly decreased lead levels in children (ages 5 to 12) who suffered from severe lead poisoning.⁸

Awards for PectaClear
PectaSol-C® MCP won the Nutritional Business Journal Product Merit Award in 2004. Dr. Eliaz was honored with an award for his Original Clinical Research presented at the Scripps Annual Conference in 2005 for his studies that indicate this new application of PectaSol-C® MCP for reducing heavy metal toxicity.