Dehydroepiandrosterone Sulfate (DHEA-S) Blood Test

Item # LC004020

Tests levels of the hormone dehydroepiandrosterone sulfate (DHEA-S)

Dehydroepiandrosterone Sulfate (DHEA-S) Blood Test  - Life Extension

Dehydroepiandrosterone Sulfate (DHEA-S) Blood Test

Item # LC004020

Tests levels of the hormone dehydroepiandrosterone sulfate (DHEA-S)

This hormone test checks your levels of DHEA sulfate, and is more stable than testing just for DHEA. Knowing your levels of DHEA-S will help you and your doctor design a supplementation regimen, hormone replacement therapy treatment, and also help assess other health factors such as risk for cardiovascular disease and more.

Dehydroepiandrosterone (DHEA) is a precursor for the sex steroids including estrogen and testosterone. It is primarily produced in the adrenal gland with a small amount secreted by the ovaries. DHEA plays an important role in immune function and stress response. A 2007 study found that DHEA reduced oxidative stress and helped to protect diabetics against the damaging effects of high blood sugar.1

Orally ingested DHEA is converted to its sulfate when passing through intestines and liver. Whereas DHEA levels naturally reach their peak in the early morning hours, dehydroepiandrosterone sulfate (DHEA-S) levels show no diurnal variation. From a practical point of view, measurement of DHEA-S is preferable to DHEA, as levels are more stable. Blood measurements of DHEA-S have a correlation with risk of death or cardiovascular disease.2

A 2008 study in the Journal of the American Geriatrics Society measured serum DHEA-S in 940 men and women ranging from age 21 to 88, following them from 1978 until 2005. The researchers found that low levels of DHEA-S showed a significant association with shorter life span and that higher levels strongly predicted longevity.3


Fasting is not required for this test. Take all medications as prescribed. If you are supplementing with any hormones, we suggest taking them approximately 2 hours prior to having your blood drawn to see peak levels. Hormones are best drawn between 8-10 AM.


  1. "DHEA Restores Oxidative Balance in Type 2 Diabetes". Medscape. Retrieved 2007-12-14.
  2. N. Engl. J. Med. 315(24):1519–24. PMID 2946952.
  3. Journal of the American Geriatrics Society 56(6):994. doi:10.1111/j.1532-5415.2008.01692.x.

The laboratory services are for informational purposes only. It is not the intention of National Diagnostics, Inc and Life Extension to provide specific medical advice but rather to provide users with information to better understand their health. Specific medical advice including diagnosis and treatment will not be provided. Always seek the advice of a trained health professional for medical advice, diagnosis or treatment.

Both the physician and the testing laboratory are independent contractors with whom National Diagnostics, Inc makes arrangements for your blood tests. Neither National Diagnostics, Inc or Life Extension will be liable for any acts or omissions of the physician, the testing laboratory, or their agents or employees.

SALE: $45.75
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It is great to be able to do specific blood tests when needed

John D, San Diego, Ca

The (DHEA-S) Blood Test was a snap. The order was processed extremely fast and the instructions provided were very clear.


Dehydroepiandrosterone Sulfate (DHEA-S) Blood Test

  • $61.00
  • Sale $45.75
  • Save 25%

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