High Potency Optimized Folate

L-Methylfolate

8500 mcg DFE, 30 vegetarian tablets Item # 01913

High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets

Click to Zoom

High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets

Click to Zoom

Thumbnail 1 of 2: High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets
Thumbnail 2 of 2: High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets

High Potency Optimized Folate

L-Methylfolate

8500 mcg DFE, 30 vegetarian tablets Item # 01913

Our High Potency Optimized Folate is a cardiovascular health supplement that also supports cognitive health and more with 8500 mcg of metabolically active 5-MTHF.
Gluten free Non-GMO Vegetarian
Always get the lowest price
and FREE SHIPPING.
Learn More
$13.50
AutoShip Price: $8.10
Save 40%
$0.27/count | 30 Day Supply

First shipment within 1 business day with FREE standard shipping.

$13.50
SALE: $8.10
Save 40%
$0.27 / count | 30 Day Supply
Buy More, Save More


Good product that I use daily. Easy to swallow tablet. Gives high dose of Folate.

David, Sedona

This has more of what I wanted than I even knew was available

MS, North Carolina

Easy to take, works well with other products I am taking.

Grammiee, Oregon

This is one of my all time favorite products!

Jill, Plymouth IN

Frequently Bought Together

  • This Item: High Potency Optimized Folate, 8500 mcg DFE, 30 vegetarian tablets
  • Vitamin B12 Methylcobalamin, 5 mg, 60 vegetarian lozenges

Total Price:

$32.10

High Potency Optimized Folate

L-Methylfolate

8500 mcg DFE, 30 vegetarian tablets

  • $13.50
  • Sale $8.10
  • Save 40%

$0.27/count | 30 Day Supply

What is High Potency Optimized Folate?

Maintaining normal levels of homocysteine, a metabolic byproduct, is associated with both cardiovascular and cognitive health. Folate, a B vitamin, helps maintain homocysteine levels already within normal range. However, not everyone can efficiently convert folate to its biologically active form. Our formula provides 5-MTHF, so you don’t have to.

The 5-MTHF folate in High Potency Optimized Folate is an ultra-bioavailable form of the B-vitamin commonly called folic acid.

High Potency Optimized Folate Benefits

  • Super high-potency dose of bioavailable 5-MTHF folate
  • Supports both cardiovascular & cognitive health
  • Helps maintain already-healthy homocysteine levels
  • 5-MTHF folate overcomes the enzyme inefficiency roadblock

For the Greatest Health Benefits

Folic acid is a common B-vitamin supplement. Once ingested, your body is supposed to convert folic acid into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that’s necessary to do this. So we formulated High Potency Optimized Folate with 8500 mcg of 5-MTHF, saving your body the trouble.

Life Extension - Why Do We Do It?

The Best Supplements Science Can Offer

When putting something in your body, you should be confident that you’re getting the nutritional benefits your body deserves. We've been delivering the highest-quality products—backed by science and formulated with the finest ingredients—for over 40 years.

What Matters to You, Matters to Us

We're committed to empowering you to live a healthier life. Whether it’s finding sustainable partners for our ingredients or funding the latest anti-aging research, we're all about your health & wellness.

Highly Recommended

98% of our customers recommend us to family and friends. We're very proud of that because our loved ones matter to us—and we're willing to bet you feel the same way.

Product Transparency

40 years of research dedicated to bringing you premium, scientifically-validated formulations.

Folic acid is the most common form of folate supplements. Once ingested, your body is supposed to convert folic acid, a synthetic version of folate, into 5-methyltetrahydrofolate, or 5-MTHF. But research shows that many people lack sufficient activity of the enzyme that's necessary to convert folic acid to 5-MTHF.1-3 A more useful approach is to take 5-MTHF directly.4-6

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

Serving Size 1 vegetarian tablet

Amount Per Serving

Folate [as (6S)-5-Methyltetrahydrofolate, calcium salt]

8500 mcg°

Other ingredients: microcrystalline cellulose, dicalcium phosphate, stearic acid, croscarmellose sodium, silica, vegetable stearate.

°DFE (dietary folate equivalents)

Non-GMO

Dosage and Use
  • Take one (1) tablet daily with food, or as recommended by a healthcare practitioner.
Caution

Consult your healthcare provider if you are at risk of vitamin B12 deficiency, as high-dose folate may mask signs.

Warnings
  • KEEP OUT OF REACH OF CHILDREN
  • DO NOT EXCEED RECOMMENDED DOSE
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Actual Size

Pill Size Image
  1. Circulation. 2015;132(1):e6-e9.
  2. European Journal of Medical Genetics. 2015;58(1):1-10.
  3. Arteriosclerosis, Thrombosis, and Vascular Biology. 1997;17(6):1157-1162.
  4. The Journal of Nutrition. 2018;148(6):885-890.
  5. The Journal of Alternative and Complementary Medicine. 2019;25(2):169-180.
  6. The FASEB Journal. 2017;31(1_supplement):lb399-lb399.
  7. The American Journal of Clinical Nutrition. 2006;84(1):156-161.
  8. The American Journal of Clinical Nutrition. 2005;82(3):627-635.
  9. Dementia and Geriatric Cognitive Disorders. 2001;12(5):309-313.

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer

Heart Health
Quiz

Heart Health
Quiz

Treat your ticker to the best cardiovascular support supplements.

Related Products