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AMPK Metabolic Activator

30 vegetarian tablets Item # 02207

AMPK Metabolic Activator, 30 vegetarian tablets

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Best Seller

AMPK Metabolic Activator

30 vegetarian tablets Item # 02207

AMPK is an enzyme found in every cell in your body. Studies show that increasing AMPK activity can encourage cells to stop storing fat and start burning it for energy—but AMPK levels decline over time.

Gluten free Non-GMO Vegetarian
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$0.80/count | 30 Day Supply

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$0.95 / count | 30 Day Supply

Excellent product, high quality, well-researched.


I have been taking it for about 4 months now and am beginning to see results


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AMPK Metabolic Activator

30 vegetarian tablets


$0.95/count | 30 Day Supply

What Is AMPK Metabolic Activator?

AMPK Metabolic Activator is our customer-favorite formula for weight management. It contains 450 mg of G. pentaphyllum (Jiaogulan) extract and 500 mg of hesperidin, a flavonoid derived from citrus fruit. Each bottle contains 30 vegetarian tablets, enough for a one-month supply at the suggested dosing of one tablet a day. AMPK Metabolic activator is gluten-free and made with 100% NON-GMO ingredients.

The G. pentaphyllum in our formula has been clinically studied to reduce stubborn abdominal fat—and we’ve augmented it with hesperidin from citrus fruit.

AMPK Metabolic Activator Benefits

  • Fight fat by encouraging cellular AMPK enzyme activity
  • Targets stubborn abdominal fat with G. pentaphyllum extract
  • Helps fight overall body fat with the citrus flavonoid hesperidin
This supplement should be taken in conjunction with a healthy diet and regular exercise program. Individual results are not guaranteed, and results may vary. Use as directed. Intended for those 18 years and older.

What is G. pentaphyllum?

G. pentaphyllum (Jiaogulan) is a climbing vine native to Asia. Its extract promotes youthful levels and activity of the AMPK enzyme.

Why did we add hesperidin?

Hesperidin is a citrus flavonoid that also activates AMPK. It supports already-healthy cholesterol levels and healthy vascular function, as well.

Targeting both Belly & Overall Fat

Abdominal fat is one of the worst types of fat. That’s where AMPK Metabolic Activator comes in: not only does the hesperidin citrus extract target overall body fat, but the G. pentaphyllum extract has been clinically studied to target abdominal fat, the type of adipose tissue we’re all trying to avoid.

AMPK Metabolic Activator

Why Should I Supplement With AMPK Metabolic Activator?

Customer: It doesn't matter what I do. I'm careful about what I eat. I drink tons of water. I exercise daily. All of this hard work—and I still can't beat the belly fat. What can I do?

Michael A. Smith, MD: As we age, our body produces less of an enzyme called AMPK, which helps to convert sugar and fat into energy. And a decline in AMPK might be a major cause for unwanted belly fat. However, studies show that if you increase AMPK activity, this can encourage your body to stop storing fat and burn it as energy. So take the fight against fat to the cellular level with Life Extension’s AMPK Metabolic Activator.

Customer: I did some research and found out that belly fat can actually speed up the normal aging process because it creates compounds that cause inflammation and oxidative stress. And who wants that? After adding AMPK Metabolic Activator to my normal routine, I've noticed a big difference. Good thing, too…because my husband just booked us a cruise, and I'm really excited to relax by the pool!

Dr. Michael A. Smith, MD: Director of Education and Spokesperson for Life Extension.

Fat can accelerate the aging process in your body.1,2 Reduced AMPK activity has been observed in fat tissue.3 That’s where promoting AMPK enzyme activity comes in.

Increasing AMPK activity

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

Serving Size 1 vegetarian tablet

Amount Per Serving

Calcium (as calcium carbonate)

130 mg

Hesperidin [from orange extract (fruit)]

500 mg

Actiponin® gynostemma extract (leaf)

450 mg

Other ingredients: microcrystalline cellulose, stearic acid, croscarmellose sodium, hydroxypropyl cellulose, aqueous film coating (hypromellose, glycerin, purified water), silica, vegetable stearate.


Actiponin® is a trademark of TG Biotech Co., Ltd.

Dosage and Use
  • Take one (1) tablet daily, or as recommended by a healthcare practitioner.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Actual Size

Pill Size Image
  1. Arterioscler Thromb Vasc Biol. 2008;28(6):1039-49.
  2. Clin Epigenetics. 2019;11(1):172.
  3. J Lipid Res. 2012;53(4):792-801.
  4. J Physiol. 2006;574(Pt 1):55-62.
  5. Obesity (Silver Spring). 2014;22(1):63-71.
  6. Food Funct. 2021;12(9):3872-3882.
  7. Nutrients. 2023;15(22)
  8. J Clin Endocrinol Metab. 2011;96(5):E782-92.

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer

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