Bio-Luteolin™
100 mg, 30 vegetarian capsules Item # 02547
Cellular function, healthy aging, enhanced bioavailability
Bio-Luteolin™
100 mg, 30 vegetarian capsules Item # 02547
Cellular function, healthy aging, enhanced bioavailability
Healthy aging starts at the cellular level. Luteolin is famous for supporting cellular function, but is hard to absorb. Our Bio-Luteolin™ formula is up to 14x times more bioavailable than regular luteolin supplements.
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What is Bio-Luteolin™?
Luteolin is a flavonoid nutrient that’s receiving significant attention in scientific circles for its potential healthy aging benefits. But like many health-promoting flavonoids, luteolin has low bioavailability. So we combined luteolin with galactomannan fibers from fenugreek seeds to increase bioavailability and maximize potential health benefits.
Luteolin is popular among healthy aging enthusiasts. This advanced formula enhances bioavailability, so you can get more of its benefits.
Bio-Luteolin™ Benefits
- Supports cellular health and healthy aging
- Shown to provide up to 14x increased bioavailability in a clinical study*
- Formulated with innovative fenugreek fiber coating to enhance absorption
*Than regular luteolin defined as 98% pure powder luteolin
Luteolin and Bioavailability: Why It Matters
Most forms of luteolin have low bioavailability. To fix this, we’ve combined luteolin with galactomannan fibers from fenugreek seeds. Doing so preserves luteolin through your digestive system, allowing it to circulate in the body: this means that Bio-luteolin is up to 14 times more bioavailable than regular forms of luteolin.
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FAQ
What is in Bio-Luteolin™?
This product provides 100 mg of our Bio-Luteolin Proprietary Blend, containing 20 mg of luteolin from Japanese sophora extract and 25 mg of galactomannans from fenugreek seed.
How does Bio-Luteolin™ work?
As we age, we experience lower rates of autophagy, a “housekeeping” process that cells use to remove old parts. Luteolin has been shown to support components of autophagy, like AMPK and mTOR, to activate this process and allow for healthy cell clean-up and function. Our Bio-Luteolin™ provides a version of luteolin that is up to 14x more bioavailable than regular luteolin.
What makes this formula more bioavailable?
Compounds like luteolin can be metabolized in the gut before the body has a chance to use them, limiting their effectiveness. That’s why our Bio-Luteolin™ contains galactomannans. This fiber from fenugreek seed surrounds luteolin to protect it from being metabolized and eliminated too quickly. This enhances bioavailability, achieving levels up to 14-fold higher than usual, meaning that the 20 mg of luteolin in this formula equates to up to 280 mg of unformulated luteolin.
MoreWho is Bio-Luteolin™ for?
Bio-Luteolin™ is intended for those who want to encourage healthy aging with a more bioavailable form of luteolin.
When is the best time to take Bio-Luteolin™? Should it be taken with food or on an empty stomach?
We suggest taking one capsule of Bio-Luteolin™ daily. It can be taken any time of the day, with or without food, based on your preference.
Will this supplement interact with my medication?
There is no indication that the nutrients within this formula would negatively interact with prescription medications. However, we always suggest that you inform your physician of any supplements you are taking.
Has this product been tested for heavy metals, contaminants, and potency?
All our raw materials and finished products go through stringent testing to meet our high-quality standards. Testing is performed for heavy metals, microbes, disintegration, potency, and quantity of active ingredients in the finished product. Only when finished products meet Life Extension’s specifications are they released for production. A finished product Certificate of Analysis (COA) can be provided upon request for all our products.
Are there any major allergens in this product?
Bio-Luteolin™ does not contain any of the 9 major allergens required on the label under the Food Allergy Safety, Treatment, Education, and Research (FASTER) Act. This means it is free of milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, sesame and soybeans.
Where is this product manufactured?
Bio-Luteolin™ is manufactured in the USA with globally sourced ingredients, in a GMP-compliant facility.
Is this product vegetarian?
Yes, this product is vegetarian and does not contain any animal-derived ingredients.
Is this product gluten-free?
Yes, this product is gluten-free.
Is this product non-GMO?
Yes, this product and all its ingredients are Life Extension verified non-GMO.
Can children take this product?
This product was designed for adults aged 18 and over. Always consult with your child’s pediatrician before giving them any supplements.
Why is luteolin gaining popularity among scientists and healthy aging enthusiasts? This flavonoid supports healthy cellular function, which is key to aging well. But luteolin is poorly absorbed, limiting its potential health benefits.1,2 Not Bio-Luteolin: this formula is shown to provide up to 14x increased bioavailability and up to 10x free luteolin than regular luteolin.3
More These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
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- KEEP OUT OF REACH OF CHILDREN
- DO NOT EXCEED RECOMMENDED DOSE
- Do not purchase if outer seal is broken or damaged.
- When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.
To report a serious adverse event or obtain product information, contact 1-866-280-2852.
Actual Size
- FEBS Lett. 1998;438(3):220-4.
- Nutrients. 2013;5(9):3367-87.
- Akay. Data on file. Bio-luteolin pharmacokinetics study. 2025.
- Akay. Data on file. Bio-luteolin efficacy study. 2025.
Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews.
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