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30 AM vegetarian tablets, 30 PM vegetarian tablets
Item# 02202

$15.40 Save $17.60


Dual-action nerve support for discomfort relief

30 AM vegetarian tablets, 30 PM vegetarian tablets
Item# 02202

SALE: $15.40 Save $17.60

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  • ComfortMAX™
  • 30 AM vegetarian tablets, 30 PM vegetarian tablets
  • Item Catalog Number: 02202

ComfortMAX™ is a unique supplement that promotes nerve health and comfort. By inhibiting inflammatory compounds to promote nerve health and encouraging healthy neurotransmitter levels in your brain, ComfortMAX™ helps to reduce discomfort. Take one convenient tablet in the morning and one at night. Live comfortably with ComfortMAX™!

Benefits at a Glance:

  • ComfortMAX™ provides dual-action nerve support to help inhibit discomfort
  • PEA inhibits inflammatory factors to promote nerve health
  • Honokiol extract supports “calming” GABA neurotransmitters affected by discomfort
  • These combined actions help you stay comfortable throughout the day
  • Morning and nighttime dosing for around-the-clock support

More facts about ComfortMAX™

According to the National Institutes of Health, nearly 25 million Americans experience daily discomfort.1 This kind of discomfort can affect mood, mobility, and quality of life.2 The reasons for physical discomfort vary, but the way we experience that discomfort doesn’t: Our peripheral nerves are responsible for delivering sensory information (an itch, temperature change, physical pressure, etc.) to the brain. And that’s where ComfortMAX™ comes in.

Palmitoylethanolamide (PEA)

Palmitoylethanolamide (or PEA) is a unique kind of fatty acid that can inhibit discomfort.3 Your body naturally produces PEA as part of a healthy inflammatory and immune response.4 In fact, PEA inhibits the secretion of inflammatory compounds from mast cells, a type of white blood cell. Overtime, our number of mast cells decreases, causing our remaining mast cells to work harder.5

That can make them overly sensitive, activating inflammatory processes linked to nerve discomfort. By inhibiting inflammatory compounds released by mast cells, PEA promotes your body’s natural response to uncomfortable nerve stimuli at the cellular level.6-8

PEA’s efficacy has been demonstrated in multiple clinical trials.9 In a randomized controlled trial following 636 patients over a period of three weeks, 600 mg of PEA every day significantly improved scores that measured relative comfort and quality of life.10 In a smaller randomized controlled trial, patients reported that PEA outperformed standard care for discomfort when taken for two weeks.11


Honokiol is a naturally occurring lignan compound derived from several species of magnolia, many of which have been used in traditional Asian medicine for centuries.12 Now, scientists are discovering that honokiol has applications for nerve health and comfort.

Honokiol has been shown to support the “calming” GABA receptors in the brain, which affects the way the brain perceives discomfort.13-15 Furthermore, honokiol is quickly taken up into the brain in animal models,16,17 making it an ideal ingredient for nerve health and comfort.

Unique Daytime & Nighttime Formula

ComfortMAX™ has been formulated to be taken twice a day, one tablet in the morning and one tablet at night right before bed, for day and night help to relief discomfort. Each package of ComfortMAX™ provides a 30 day supply. Try ComfortMAX™ today!

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

  1. J Pain. 2015;16(8):769-80.
  2. J Pain Res. 2016;9:457-467.
  3. Pain Physician. 2016;19(2):11-24.
  4. CNS Neurol Disord Drug Targets. 2013;12(1):78-83.
  5. Adv Gerontol. 2017;7(1):68-75.
  6. Eur J Pharmacol. 1996;300(3):227-36.
  7. Brain Behav Immun. 2011;25(6):1099-112.
  8. CNS Neurol Disord Drug Targets. 2013;12(1):34-44.
  9. Br J Clin Pharmacol. 2016;82(4):932-42.
  10. Dolor. 2010;25(1):35-42.
  11. J Orofac Pain. 2012;26(2):99-104.
  12. J Nat Prod. 1998;61(1):135-8.
  13. Neuropharmacology. 2012;62(8):2507-14.
  14. Neurochem Res. 1999;24(12):1593-602.
  15. Adv Pharmacol. 2006;54:1-27.
  16. Eur J Drug Metab Pharmacokinet. 2016;41(5):587-94.
  17. PLoS One. 2011;6(4):e18490.


Supplement Facts

Serving Size 1 AM vegetarian tablet (white)

Amount Per Serving

Calcium (as calcium carbonate)

60 mg

Palmitoylethanolamide (PEA)

600 mg

Other ingredients: microcrystalline cellulose, croscarmellose sodium, hydroxypropyl methylcellulose, stearic acid, vegetable stearate, silica, maltodextrin, hydroxypropyl cellulose, glycerin.

Supplement Facts

Serving Size 1 PM vegetarian tablet (blue)

Amount Per Serving

Calcium (as calcium carbonate)

30 mg

Palmitoylethanolamide (PEA)

600 mg

Honokiol [from magnolia extract (bark)]

180 mg

Other ingredients: croscarmellose sodium, microcrystalline cellulose, hydroxypropyl methylcellulose, stearic acid, hydroypropyl cellulose, vegetable stearate, silica, maltodextrin, spirulina extract color, glycerin.


Dosage and Use
  • Take one (1) AM tablet in the morning and one (1) PM tablet before bed, with or without food, or as recommended by a healthcare practitioner.

The blue PM tablet may cause mild sedation in some people. Take at bedtime.



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