Protein Electrophoresis, serum (SPE) Blood Test

  • Item # LC001487

Measures albumin and globulin protein fractions in blood serum

Protein Electrophoresis, serum (SPE) Blood Test  - Life Extension

Protein Electrophoresis, serum (SPE) Blood Test

  • Item # LC001487

Measures albumin and globulin protein fractions in blood serum

The primary use of this test is to evaluate for multiple myeloma, a type of blood cancer. The test measures specific proteins of the blood, analyzing fractions of blood serum’s two major protein groups, albumin and globulin.

The serum protein electrophoresis (SPE) test measures specific proteins in the blood.

Blood serum contains two major protein groups: albumin and globulin. Using protein electrophoresis, these two groups can be separated into five smaller fractions:

  • Albumin
  • Alpha-1 globulin
  • Alpha-2 globulin
  • Beta globulin
  • Gamma globulin

The primary use of this test is in the evaluation of multiple myeloma; a cancer of white blood cells responsible for producing antibodies. Symptoms of multiple myeloma include bone pain, anemia, fatigue, unexplained fractures, and/or recurrent infections,

Other applications of SPE include the following:

  • Follow up when tests such as serum protein or calcium levels are abnormal
  • Follow up to low white or red blood cell counts
  • Symptoms of kidney or liver diseases
  • Symptoms of autoimmune diseases
  • Symptoms of inflammatory conditions
  • Acute or chronic infections


Fasting is not required. Take all medications as prescribed.

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Protein Electrophoresis, serum (SPE) Blood Test


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