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1000 mg, 100 vegetarian capsules
Item# 01669



Amino acid that promotes healthy sleep

1000 mg, 100 vegetarian capsules
Item# 01669


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  • Glycine
  • 1000 mg, 100 vegetarian capsules
  • Item Catalog Number: 01669

Glycine is a conditionally essential amino acid that serves as both an inhibitory and excitatory neurotransmitter.1-3 It is the chemically simplest and most omnipresent of all the amino acids. It combines with many toxic substances, converting them to harmless forms which are then excreted.4,5

This amino acid has a calming effect on the brain and is also involved in growth.6-15 Research suggests that glycine may help promote deeper sleep.3,7,8 Glycine also has a positive impact on attention and memory in adults.6-19 Glycine may also help boost the immune defense system and has oxidative stress regulating effects.20-23

Most people need to take between one to three grams of glycine to be effective even though studies show high doses are safe.24,25 However, most glycine products are only available in 500 mg capsules. That makes taking higher doses cumbersome and costly. However, Life Extension’s glycine comes in easy-to-swallow 1000-mg capsules.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

  1. J Physiol. 2012 Nov 15;590(Pt 22):5749-64. doi: 10.1113/jphysiol.2012.241299. 
  2. Pain. 2010 Nov;151(2):356-65. 
  3. J Pharmacol Sci. 2012;118(2):145-8. 
  4. Expert Opin Drug Metab Toxicol. 2007 Apr;3(2):159-68. 
  5. Curr Drug Metab. 2011;12(2):104-23. 
  6. Acta Endocrinol (Copenh). 1980 Mar;93(3):283-6.
  7. PLoS One. 2011;6(9):e25076. 
  8. Psychiatry Clin Neurosci. 2011 Mar;65(2):142-9.
  9. Sleep. 2008 Nov;31(11):1483-6. 
  10. J Clin Psychopharmacol. 1999 Dec;19(6):506-12.
  11. Endocrinologie. 1979 Jul-Sep;17(3):201-4.
  12. Glycine as a neurotransmitter. Psychopharmacaology: A Generation of progress. New York: Raven Press; 1978, 333-46.
  13. Bioprocess Biosyst Eng. 2011 Sep 25. [Epub ahead of print] 
  14. Am J Clin Nutr. 2002 Dec;76(6):1302-7.
  15. J Endocrinol Invest. 2003;26(10 Suppl):16-26.
  16. Psychiatr Pol. 2010 May-Jun;44(3):395-404.
  17. Pain. 2011 Apr;152(4):809-17.
  18. Sleep. 2008 November 1; 31(11): 1487–1491. 
  19. Nutr Neurosci. 2003 Oct;6(5):269-75.
  20. Antimicrob Agents Chemother. 2004 Oct;48(10):3782-8.
  21. Rev Alerg Mex. 2006 Nov-Dec;53(6):212-6.
  22. Cell Biochem Funct. 2004 Mar-Apr;22(2):123
  23. Pharmazie. 2004 Jan;59(1):55-60.
  24. Psychiatry Res. 2009 August 30; 173(2): 143-149. 
  25. Biol Psychiatry. 2004 Jan 15;55(2):165-71


Supplement Facts

Serving Size 1 vegetarian capsules

Amount Per Serving


1000 mg

Other ingredients: vegetable cellulose (capsule), ascorbyl palmitate.

Dosage and Use
  • Take one (1) to three (3) capsules on an empty stomach at bedtime, or as recommended by a healthcare practitioner.


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