This formulation combines vitamins B2 (riboflavin), B6 (pyridoxal 5’-phosphate), B12 (as methylcobalamin) and folate as L-5-methyltetrahydrofolate (L-5-MTHF).

Folate (L-5-MTHF)

Folate helps maintain homocysteine levels within the normal range, which promotes cardiovascular health.^1,7,8 Folate supports neurotransmitter synthesis as well, which is an essential part of cognitive health.⁹ People with healthy homocysteine levels have a greater chance of maintaining healthy cognitive function.^10,11

But not everyone’s body can utilize traditional folate supplements. Research shows that a large part of the population cannot convert folate to its bioactive 5-MTHF form (L-5-methyltetrahydrofolate), leaving many vulnerable to low blood folate levels (and higher-than-desired homocysteine).¹² So Homocysteine Resist delivers 8500 mcg of 5-MTHF in each capsule.

Vitamin B6 (pyridoxal 5'-phosphate)

Vitamin B6 also facilitates neurotransmitter synthesis, as well as amino acid and lipid metabolism.⁹ Traditional forms of B6 must be converted to pyridoxal 5'-phosphate before your body can use it, but Homocysteine Resist contains 100 mg of pyridoxal 5'-phosphate that’s ready to work right from the start.⁹

Vitamin B2 (riboflavin) and Vitamin B12 (methylcobalamin)

The body naturally converts vitamin B2 (riboflavin) to its riboflavin-5'-phosphate form, which it then uses for energy production.¹³ Vitamin B12 supports nerve cell growth and heart health by helping to maintain healthy homocysteine levels already within normal range.^14,15 And methylcobalamin is the form of B12 biologically active in your brain.¹⁶