Senolytic Activator®

36 vegetarian capsules Item # 02301

Senolytic Activator® , 36 vegetarian capsules

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Senolytic Activator®, 36 vegetarian capsules

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Senolytic Activator®

36 vegetarian capsules Item # 02301

Our Senolytic Activator® combines black tea theaflavins, the plant-derived flavonoid apigenin, and ultra-absorbable forms of the bio-flavonoids quercetin and fisetin to help manage senescent cell burden and promote systemic rejuvenation.

Gluten free Non-GMO Vegetarian
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$0.50/count | 84 Day Supply

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$0.54 / count | 84 Day Supply

I plan on using this for the rest of my life. At age 87, I am quite active.


New woman. I love this product.

No longer looking older than I am, AL

I would purchase this product consistently. Great product for anti-aging.


Well researched.


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Senolytic Activator®

36 vegetarian capsules


$0.54/count | 84 Day Supply

What Is Senolytic Activator?

Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them. Senolytic compounds selectively target senescent cells.

Black tea theaflavins, apigenin, quercetin and fisetin all target different biological pathways, helping to manage senescent cells.

Senolytic Activator Benefits

  • Helps the body manage senescent cells
  • Promotes youthful, healthy cellular function
  • Supports systemic rejuvenation
  • Made with black tea theaflavins, apigenin, plus highly absorbable quercetin and fisetin
  • Convenient once-a-week dosing

Ultra-absorbable Quercetin and Fisetin

These two plant flavonoids have many health benefits, but traditional forms are hard to absorb. So we use quercetin and fisetin that are  much, much more bioavailable. The plant-based flavonoid apigenin is included since it complements the senolytic activity of quercetin and black tea compounds.

Life Extension - Why Do We Do It?

The Best Supplements Science Can Offer

When putting something in your body, you should be confident that you’re getting the nutritional benefits your body deserves. We've been delivering the highest-quality products—backed by science and formulated with the finest ingredients—for over 40 years.

What Matters to You, Matters to Us

We're committed to empowering you to live a healthier life. Whether it’s finding sustainable partners for our ingredients or funding the latest anti-aging research, we're all about your health & wellness.

Highly Recommended

98% of our customers recommend us to family and friends. We're very proud of that because our loved ones matter to us—and we're willing to bet you feel the same way.

Product Transparency

40 years of research dedicated to bringing you premium, scientifically-validated formulations.

Cellular senescence is a natural part of the aging process in which cells no longer function optimally. Senescent cells can accumulate over time, affecting the day-to-day function of the healthy cells around them.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

Serving Size 3 vegetarian capsules

Servings Per Container 12

Amount Per Serving
Bio-Fisetin Proprietary Blend 312 mg
Providing 18% fisetin (56 mg) [from wax tree extract (stem)], 35% galactomannans (109 mg) [from fenugreek (seed)]  
Theaflavins [from decaffeinated black tea extract (leaf)] 275 mg
Bio-Quercetin® Proprietary Blend providing 35% quercetin (25 mg) [from Japanese sophora concentrate (flower bud)], 30% galactomannans (20 mg) [from fenugreek (seed)] 74 mg


50 mg

Other ingredients: sunflower lecithin, vegetable cellulose (capsule), microcrystalline cellulose, silica, vegetable stearate, sunflower oil.


Dosage and Use
  • Take three (3) capsules once weekly, or as recommended by a healthcare practitioner.
  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Actual Size

Pill Size Image
  1. Exp Gerontol. 2015;68:19-25.
  2. Free Radic Biol Med. 2017;113:59-70.
  3. Pharmacol Res. 2012;66(4):363-73.
  4. Aging Cell. 2015;14(4):644-58.
  5. Oxid Med Cell Longev. 2009;2(5):270-8.
  6. Cardiovasc Res. 2007;73(2):348-58.
  7. Nutrients. 2016;8(3):167.
  8. Trends in Food Science & Technology. 2016;56:21-38.
  9. EBioMedicine. 2018;36:18-28.
  10. NPJ Aging Mech Dis. 2016;2:16017.
  11. Mini Rev Med Chem. 2018;18(13):1151-1157.
  12. Nutr Res Pract. 2017;11(5):430-434.
  13. Biochem Biophys Res Commun. 2015;467(4):638-44.
  14. Life Sci. 2018;193:171-179.
  15. Int Immunopharmacol. 2017;45:135-147.
  16. Akay Group. A cross over pilot pharmacokinetic study of Fisetin 1000mg and Formulated Fisetin 200 mg administered in a single dose to healthy volunteers. Unpublished study from supplier.
  17. Nat Med. 2015;21(12):1424-35.
  18. Biochem Pharmacol. 2015;96(4):337-48.

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer



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