Best In Class


60 AM/PM vegetarian tablets Item # 02202

ComfortMAX™, 60 AM/PM vegetarian tablets

Click to Zoom

ComfortMAX™, 60 AM/PM vegetarian tablets

Click to Zoom

Thumbnail 1 of 2: ComfortMAX™, 60 AM/PM vegetarian tablets
Thumbnail 2 of 2: ComfortMAX™, 60 AM/PM vegetarian tablets
Best In Class


60 AM/PM vegetarian tablets Item # 02202

PEA inhibits inflammatory factors to support nerve cell health. Honokiol encourages healthy levels of calming neurotransmitters in the brain. Together, they help alleviate minor discomfort.
Gluten free Non-GMO Vegetarian
Always get the lowest price
Learn More
AutoShip Price: $29.00
Save 12%
$0.48/count | 30 Day Supply

First shipment within 1 business day with FREE standard shipping.

SALE: $33.00
Save 0%
$0.55 / count | 30 Day Supply

This stuff really works

Jimmy, Cedarville

I have been using ComfortMAX now for over a month. Very effective results.

Seascout, Seattle

You May Also Like


60 AM/PM vegetarian tablets


$0.55/count | 30 Day Supply

What Is ComfortMAX?

ComfortMAX™ delivers two potent ingredients: palmitoylethanolamide (PEA) and honokiol, a compound derived from Magnolia bark. By promoting nerve comfort in two separate yet complementary ways, the ingredients in ComfortMAX™ help to inhibit nerve discomfort.

The reasons for physical discomfort vary, but the way we experience that discomfort doesn't. That's why we’ve created ComfortMAX™.

ComfortMAX™ Benefits

  • Dual-action formula helps alleviate minor nerve discomfort
  • Helps you stay comfortable throughout the day
  • Provides morning and nighttime doses for around-the-clock support

What is PEA?

Palmitoylethanolamide (PEA) is a fatty acid your body produces as part of a healthy inflammatory and immune response. PEA can inhibit occasional minor discomfort.

Why did we add honokiol?

Honokiol is a lignan compound derived from several species of magnolia. Its calming effect on nerve receptors helps to alleviate discomfort.

The How & Why Behind ComfortMAX™

By inhibiting inflammatory compounds to promote nerve health and encouraging healthy neurotransmitter levels in your brain, ComfortMAX™ helps to reduce discomfort. Formulated to be taken twice a day, one tablet in the morning and one tablet at night right before bed, it helps with relieving discomfort—day and night.

Life Extension - Why We Do It?

The Best Supplements Science Can Offer

When putting something in your body, you should be confident that you’re getting the nutritional benefits your body deserves. We've been delivering the highest-quality products—backed by science and formulated with the finest ingredients—for over 40 years.

What Matters to You, Matters to Us

We're committed to empowering you to live a healthier life. Whether it’s finding sustainable partners for our ingredients or funding the latest anti-aging research, we're all about your health & wellness.

Highly Recommended

98% of our customers recommend us to family and friends. We're very proud of that because our loved ones matter to us—and we're willing to bet you feel the same way.

Product Transparency

40 years of research dedicated to bringing you premium, scientifically-validated formulations.

According to the National Institutes of Health, nearly 25 million Americans experience daily discomfort.1 This kind of discomfort can affect mood, mobility and quality of life.2 The reasons for physical discomfort vary, but the way we experience that discomfort doesn’t: Our peripheral nerves are responsible for delivering sensory information (an itch, temperature change, physical pressure, etc.) to the brain. And that’s where ComfortMAX™ comes in.

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

Serving Size 1 AM vegetarian tablet (white)

Amount Per Serving

Calcium (as calcium carbonate)

60 mg

Palmitoylethanolamide (PEA)

600 mg

Other ingredients: microcrystalline cellulose, coating (purified water, hypromellose, glycerin), croscarmellose sodium, silica, stearic acid, vegetable stearate, maltodextrin.

Serving Size 1 PM vegetarian tablet (blue)

Amount Per Serving

Calcium (as calcium carbonate)

30 mg

Palmitoylethanolamide (PEA)

600 mg

Honokiol [from magnolia extract (bark)]

180 mg

Other ingredients: microcrystalline cellulose, croscarmellose sodium, vegetable stearate, silica, spirulina extract, stearic acid, trehalose, coating (purified water, hypromellose, glycerin), maltodextrin.


Dosage and Use
  • Take one (1) AM tablet in the morning and one (1) PM tablet before bed, or as recommended by a healthcare practitioner.

The blue PM tablet may cause mild sedation in some people. Take at bedtime.

  • Do not purchase if outer seal is broken or damaged.
  • When using nutritional supplements, please consult with your physician if you are undergoing treatment for a medical condition or if you are pregnant or lactating.

To report a serious adverse event or obtain product information, contact 1-866-280-2852.

Actual Size

Pill Size Image
  1. J Pain. 2015;16(8):769-80.
  2. J Pain Res. 2016;9:457-467.
  3. Pain Physician. 2016;19(2):11-24.
  4. CNS Neurol Disord Drug Targets. 2013;12(1):78-83.
  5. Adv Gerontol. 2017;7(1):68-75.
  6. Eur J Pharmacol. 1996;300(3):227-36.
  7. Brain Behav Immun. 2011;25(6):1099-112.
  8. CNS Neurol Disord Drug Targets. 2013;12(1):34-44.
  9. Br J Clin Pharmacol. 2016;82(4):932-42.
  10. Dolor. 2010;25(1):35-42.
  11. J Orofac Pain. 2012;26(2):99-104.
  12. J Nat Prod. 1998;61(1):135-8.
  13. Adv Pharmacol. 2006;54:1-27.
  14.  Neuropharmacology. 2012;62(8):2507-14.
  15. Neurochem Res. 1999;24(12):1593-602.
  16. Eur J Drug Metab Pharmacokinet. 2016;41(5):587-94.
  17. PloS one. 2011;6(4):e18490.

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Full product reviews disclaimer

Nerve Health

Nerve Health

How are you feeling…literally? Answer these questions for nerve health suggestions.

Related Products