Best In Class

Optimized Resveratrol

  • 60 vegetarian capsules
  • Item # 02230
Best In Class

Optimized Resveratrol

  • 60 vegetarian capsules
  • Item # 02230

Activate your longevity genes

Our best-in-class Optimized Resveratrol formula contains trans-resveratrol as well as complementary phytonutrients fisetin and quercetin to promote longevity and give you other resveratrol benefits.
Gluten free Non-GMO
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We will continue using the product. We both noticed a difference.

Loving Life, Fairfield, CA

I have been using it for years. I find it tends to keep me feeling healthy.

MJS, Florida

Critically important supplement for my longevity program.

FTBDVM, Wakefield, VA

I take Resveratrol every day with my other vitamins and feel fantastic.

Sue, Surprise, AZ

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Optimized Resveratrol

60 vegetarian capsules

  • $33.75
  • Sale $30.38
  • Save 10%

$0.51/count | 60 Day Supply

What Is Optimized Resveratrol?

Optimized Resveratrol combines 250 mg of resveratrol with complementary plant compounds. Together, these ingredients promote the expression of genes associated with healthy aging. These so-called longevity genes encourage the healthy structure and function of cells and organs throughout the body.

Resveratrol from red grapes is one possible contributor to the potential health benefits of moderate red wine consumption.

Optimized Resveratrol Benefits

  • Promotes youthful gene expression similar to calorie-restricted diets
  • Supports healthy insulin response & mitochondrial function
  • Helps maintain already-healthy glucose levels
  • Supports a healthy inflammatory response & helps inhibit oxidation
  • Contains a grape & wild blueberry fruit blend for additional benefits

What is resveratrol?

Found in red grapes, as well as Japanese knotweed, resveratrol is a plant compound that promotes and maintains optimal health and longevity.

Why did we add fisetin?

Fisetin promotes cardiovascular health, combats oxidative stress and encourages a healthy inflammatory response.

Optimized Resveratrol

Why Should I Supplement With Optimized Resveratrol?

"The grapes used to make red wine contain resveratrol, which has been shown to promote and maintain optimal health and longevity. But research associated with deriving these health benefits from drinking red wine is unclear at best.

Based on several longevity studies, we developed our most advanced resveratrol formula, Optimized Resveratrol. It promotes youthful gene expression and healthy insulin sensitivity. It also supports a healthy inflammatory response and cardiovascular activity."

Dr. Michael A. Smith, MD: Director of Education and Spokesperson for Life Extension.

Resveratrol helps promote and maintain optimal health and longevity.1 Our Optimized Resveratrol formula contains trans-resveratrol, the form abundant in red wine and associated with beneficial biological effects.2-5 Resveratrol also promotes healthy insulin sensitivity, encourages enhanced mitochondrial function, supports a healthy inflammatory response and has demonstrated beneficial cardiovascular activity.6-8

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.
  1. Clin Interv Aging. 2008;3(2):331-9.
  2. Nutrient Delivery. Academic Press; 2017:413-456
  3. Chemistry Central Journal. 2011;5(88):1-6.
  4. Micronutrient Information Center. 2015;2018(04/23/2018)
  5. Mol Nutr Food Res. 2005;49(5):495-504.
  6. Cell Mol Life Sci. 2015;72(8):1473-88.
  7. Biochim Biophys Acta. 2015;1852(6):1145-54.
  8. Obes Rev. 2016;17(12):1329-1340.
  9. Genes Nutr. 2009;4(4):297-307.
  10. Adv Exp Med Biol. 2016;928:213-244.
  11. Life Sci. 2018;194:75-87.
  12. Pharmacogn Rev. 2016;10(20):84-89.
  13. J Am Coll Cardiol. 2016;67(13_S):2003-2003.
  14. Nutrients. 2016;8(9)
  15. Molecules. 2017;22(2)

Serving Size 1 vegetarian capsule

Amount Per Serving

Trans-Resveratrol [from Japanese knotweed (root)]

250 mg

Quercetin (as quercetin dihydrate)

150 mg

Grape (fruit) and wild blueberry (fruit) blend [providing polyphenols, anthocyanins, OPCs]

85 mg

Fisetin [from wax tree extract (stem)]

10 mg

Other ingredients: vegetable cellulose (capsule), microcrystalline cellulose, vegetable stearate, silica, maltodextrin.


Dosage and Use
  • Take one (1) capsule daily, or as recommended by a healthcare practitioner.

Actual Size

Pill Size Image

Product reviews are provided for informational purposes only and reflect solely the views and opinions expressed by the contributors and not those of Life Extension. We do not verify or endorse any claims made in these reviews. Please read the full product reviews disclaimer.

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