R-lipoic Acid

100 mg, 60 capsules Item # 28539

R-lipoic Acid 100 mg, 60 capsules - Life Extension

R-lipoic Acid

100 mg, 60 capsules Item # 28539

Alpha-lipoic acid consists of two different forms (isomers) that have vastly different properties. The R form is the biologically active component (native to the body) that is responsible for lipoic acid’s phenomenal antioxidant effect. The S form is produced from chemical manufacture and is not very biologically active. Alpha-lipoic acid supplements typically consist of the R and S form in a 50/50 ratio. That means a 100 mg alpha-lipoic acid supplement is providing 50 mg of the biologically active R form.

The human body normally produces and uses the R form of lipoic acid. This active form, R-lipoic acid, significantly supports healthy inflammatory response1-3, is a potent free-radical scavenger and has been shown to be more potent than the combined “R” and “S” forms that ordinarily comprise alpha-lipoic acid supplements.4-11

  1. Skin Pharmacol. 1994;7(5):278-84.
  2. Circulation. 2008 Jan 22;117(3):421-8. Epub 2007 Dec 24.
  3. Wien Klin Wochenschr. 2006 Mar;118(3-4):100-7.
  4. Eur J Pharm Sci. 1999 Apr;8(1):57-65.
  5. Free Radic Biol Med. 1999 Mar;26(5-6):685-94.
  6. Biochem Mol Biol Int. 1998 Oct;46(3):585-95.
  7. Am J Physiol. 1997 Jul;273(1 Pt 1):E185-E191.
  8. Biochem Biophys Res Commun. 1996 Apr 16;221(2):422-9.
  9. Biochem Pharmacol. 1996 Feb 9;51(3):233-8.
10.  J Mol Cell Cardiol. 1995 Sep;27(9):1895-903.
11. Z Naturforsch [C]. 1994 Sep-Oct;49(9-10):691-2.
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Serving Size 1 capsule

Servings Per Container 60

Amount Per Serving

R-alpha Lipoic Acid (thioctic acid)

100 mg

Other Ingredients: Cellulose (capsule shell), cellulose, magnesium stearate, stearic acid, silica.

Does not contain: Yeast, corn, wheat, soy, gluten, milk, sugar, preservatives or artificial color.

Dosage and Use

Adults take one capsule daily with food or as directed by a health care professional. As a reminder, discuss the supplements and medications that you take with your health care providers.


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R-lipoic Acid

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