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Skin Protection Effects Of Vitamin E

August 2012

By Robert Goldfaden And Gary Goldfaden, MD


1. Fuchs J, Weber S, Podda M, et al. HPLC analysis of vitamin E isoforms in human epidermis: correlation with minimal erythema dose and free radical scavenging activity. Free Radic Biol Med. 2003 Feb 1;34(3):330-6.

2. Traber MG, Podda M, Weber C, Thiele J, Rallis M, Packer L. Diet-derived and topically applied tocotrienols accumulate in skin and protect the tissue against ultraviolet light-induced oxidative stress. Asia Pac J Clin Nutr. 1997;6(1):63-7.

3. Wang X, Quinn PJ. Vitamin E and its function in membranes. Prog Lipid Res. 1999 Jul;38(4):309-36.

4. Buettner GR. The pecking order of free radicals and antioxidants: lipid peroxidation, alpha-tocopherol, and ascorbate. Arch Biochem Biophys. 1993 Feb 1;300(2):535-43.

5. Packer L, Witt EH, Tritschler HJ. alpha-Lipoic acid as a biological antioxidant. Free Radic Biol Med. 1995 Aug;19(2): 227-50.

6. Packer L, Weber SU, Rimbach G., Molecular aspects of alpha-tocotrienol antioxidant action and cell signaling. J Nutr. 2001 Feb;131(2):369S-73S.

7. Shibata A, Nakagawa K, Kawakami Y, Tsuzuki T, Miyazawa T. Suppression of gamma-tocotrienol on UVB induced inflammation in HaCaT keratinocytes and HR-1 hairless mice via inflammatory mediators multiple signaling. J Agric Food Chem. 2010 Jun 9;58(11):7013-20.

8. Michihara A, Ogawa S, Kamizaki Y, Akasaki K. Effect of-tocotrienol on melanin content and enzymes for melanin synthesis in mouse melanoma cells. Biol Pharm Bull. 2010;33(9):1471-6.

9. Trivedi JS, Krill SL, Fort JJ. Vitamin E as a human skin penetration enhancer. Eur J Phann Sci. 1995;3:241-3.

10. Brigelius-Floh R, Traber MG. Vitamin E: function and metabolism. FASEB. 1999 Jul;13(10):11455.

11. Clarke MW, Burnett JR, Croft KD. Vitamin E in human health and disease. Crit Rev Clin Lab Sci. 2008;45(5):417-50.

12. Serbinova E, Kagan V, Han D, Packer L. Free radical recycling and intramembrane mobility in the antioxidant properties of alpha-tocopherol and alpha-tocotrienol. Free Radic Biol Med. 1991;10(5):263-75.

13. Passwater R. Health benefits beyond vitamin E activity: solving the tocotrienol riddle. An interview with Dr. Barrie Tan. Whole Foods Magazine. 2008.