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Health Protocols

Maintaining a Healthy Microbiome

Probiotics And Mood

A randomized controlled clinical trial, which examined participants with low urinary free cortisol levels, reported that Lactobacillus helveticus R0052 and Bifidobacterium longum R0175 improved mental well-being, and could have a preventive role against stress-related psychological changes (Messaoudi, Violle 2011).

In a double-blind placebo-controlled clinical trial on human volunteers, a probiotic formulation containing L. helveticus R0052 and B. longum R0175, taken for 30 days, led to beneficial psychological effects, including improvements in scales that measure depression, anger-hostility, and problem solving. This same probiotic combination also reduced anxiety-like behavior in rats (Messaoudi, Lalonde 2011). In another rat model, the combination of probiotics reduced depression scores after a heart attack and restored gut permeability (Arseneault-Breard 2012), and it decreased cell death in various brain regions (Girard 2009). In mice, it prevented brain changes that occur as a result of chronic psychological stress (Ait-Belgnaoui 2014).


Disclaimer and Safety Information

This information (and any accompanying material) is not intended to replace the attention or advice of a physician or other qualified health care professional. Anyone who wishes to embark on any dietary, drug, exercise, or other lifestyle change intended to prevent or treat a specific disease or condition should first consult with and seek clearance from a physician or other qualified health care professional. Pregnant women in particular should seek the advice of a physician before using any protocol listed on this website. The protocols described on this website are for adults only, unless otherwise specified. Product labels may contain important safety information and the most recent product information provided by the product manufacturers should be carefully reviewed prior to use to verify the dose, administration, and contraindications. National, state, and local laws may vary regarding the use and application of many of the treatments discussed. The reader assumes the risk of any injuries. The authors and publishers, their affiliates and assigns are not liable for any injury and/or damage to persons arising from this protocol and expressly disclaim responsibility for any adverse effects resulting from the use of the information contained herein.

The protocols raise many issues that are subject to change as new data emerge. None of our suggested protocol regimens can guarantee health benefits. The publisher has not performed independent verification of the data contained herein, and expressly disclaim responsibility for any error in literature.

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