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Life Extension Mix™ Tablets with Extra Niacin

240 Tablets
Item# 02357


Life Extension Mix™ Tablets with Extra Niacin

State-of-the-art multi-nutrient formula

240 Tablets
Item# 02357


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  • Life Extension Mix™ Tablets with Extra Niacin
  • 240 Tablets
  • Item Catalog Number: 02357

Studies show that people who eat the most fruits and vegetables enjoy healthier and longer lives, but getting the recommended five servings a day is difficult for even the healthiest diets. That's why we created Life Extension Mix™, a daily supplement that provides all the high-potency vitamins and minerals needed to form the cornerstone of a comprehensive health maintenance program.

Benefits at a Glance:

  • Provides a full spectrum of essential nutrients needed for whole-body health
  • Promotes cellular DNA function
  • Maintains already-normal glycemic control
  • Helps inhibit LDL oxidation

Our formula saves time and money by combining the most important nutrients — including unique vegetable, fruit, and botanical extracts — into one product, eliminating the need to take dozens of separate supplements.

More facts about Life Extension Mix

Life Extension Mix™ is a state-of-the-art multi-nutrient formula jam-packed with the purest and most potent forms of vitamins, minerals, amino acids, and unique vegetable, fruit, and botanical extracts. In every daily dose of Life Extension Mix™, you'll get an extensive array of nutrients:

Bioactive quercetin phytosome

Life Extension Mix™ contains 5 mg of quercetin that has been integrated into a phytosome. A phytosome is a phospholipid sphere that encases a botanical compound, aiding in its absorption and making it more bioavailable: this quercetin is up to 50 times more bioavailable than standard quercetin. Quercetin supports cellular health, endothelial health, and healthy immune function.


Found in dark red fruits, delphinidins are potent anthocyanin compounds that activate the production of nitric oxide, promoting vascular relaxation and blood pressure support.1–4 They can also help inhibit inflammatory factors5–8 and glycation,9 support immune health, and help maintain healthy blood sugar levels within normal range.

Pyridoxal 5'-phosphate

Glycation is a normal part of the aging process that can affect your health.10–14 To help inhibit glycation, each daily dose of Life Extension Mix™ provides 100 mg of pyridoxal 5'-phosphate — a metabolically active B6 that has been shown to help inhibit glycation reactions. 15-17

Standardized pomegranate extract

Pomegranate supports healthy cardiovascular function32-37 and DNA structure in prostate cells.18-23 Our pomegranate extract is standardized to provide the biologically active punicalagins that are so unique to this fruit. These punicalagins are 100% water-soluble, have a remarkable 95% absorption rate,24 and are highly potent at inhibiting free radicals.25

Blueberry extracts

Blueberry anthocyanin compounds help inhibit free radicals, while blueberry's other active constituents promote healthy lipid and glucose levels for those already within normal range.26-29 Even more exciting: these blueberry constituents may help protect DNA structure. 30-34 Life Extension Mix™ features the wild blueberry extract packed with active blueberry constituents.

Standardized green tea extract

In recent years, the active polyphenol compounds in green tea have been found to help inhibit LDL oxidation, neuronal peroxidation, and help maintain healthy DNA structure.35-44 Life Extension Mix's daily dose contains 325 mg of a decaffeinated green tea extract standardized to provide 98% of the active polyphenols that scientists attribute to green tea's multiple health benefits.

Standardized vegetable extracts

Life Extension Mix™ offers a wide array of vegetable extracts, including 8 mg of luteolin, a flavonoid found in parsley, basil, celery, and other foods. Luteolin has been shown to inhibit DNA oxidation45 and to inhibit excess levels of cytokines such as interleukin-4 and interleukin-13.46

Our formula features a concentrated broccoli mixture with standardized extracts of sulforaphane and glucosinolates, compounds attributed to broccoli's detoxification, DNA,47-50 and other health benefits, 51-71 as well as chlorophyll.72-83A daily dose also provides 200 mg of calcium D-glucarate (supplying 175 mg of D-glucarate), a phytonutrient found in grapefruit, apples, oranges, broccoli, and Brussels sprouts. D-glucarate supports detoxification processes.84-86

Life Extension Mix™ also contains lutein and lycopene. Lutein, an extract found in in leafy greens such as kale and spinach, has been shown to help maintain critical pigments in the eye macula.87 Lycopene from tomatoes helps to maintain DNA structure and protect against LDL oxidation. 88-98

Standardized fruit extracts

In addition to our standardized pomegranate and wild blueberry extracts, Life Extension Mix™ also features fruit extracts such as bilberry, grape seed, and citrus bioflavonoids to promote healthy circulation help maintain healthy DNA.

Our unique formula is fortified with maqui berry and tart cherry for their antioxidant benefits for heart health as well as muscle and joint function support.99-118 It also includes a customized blend of blackberry, cranberry, plum, elderberry, persimmon, cherry, and other fruits that studies indicate provide multiple favorable effects on the body.

Numerous studies have pointed toward the many benefits of olive polyphenols, and Life Extension Mix™ contains an olive extract standardized to provide polyphenols like hydroxytyrosol that have been shown to help inhibit LDL oxidation, free radicals, and promote healthy cell membranes. 119-131

Sesame seed lignan extract

Sesame lignans promote healthy levels of gamma tocopherol, 132,133 enhance the beneficial effects of fish oils, and helping to maintain already-normal cholesterol/LDL levels.134-143 Life Extension Mix™ provides 10 mg of a sesame lignan extract to supply the direct benefits of the lignans and to augment the effects of vitamin E174 and other nutrients such as gamma-linolenic acid (GLA).

Nutrients to maintain healthy blood glucose levels

Chromium, magnesium, and biotin help maintain healthy blood sugar for those already within normal range.145-156 In addition to highly absorbable forms of magnesium and biotin, Life Extension Mix™ contains 500 mcg of Crominex® 3+, a biologically active chromium complex. Studies on the benefits of chromium supplementation show that doses exceeding 200 mcg a day are required for optimal effects.157-159

High-potency vitamin D3

Researchers today are concerned that many people are not supplementing with enough vitamin D, a critical nutrient for maintaining bone density and healthy cell division.160-167 Currently, most experts in the field believe that intakes of between 1,000 and 10,000 IU for adults will lead to a more healthy level of serum 25(OH)D, at approximately 50-80 ng/mL.168-170

Each daily dose of Life Extension Mix™ provides 2,000 IU of vitamin D3. What's more, this formula contains only 500 IU of preformed vitamin A. Preformed (not beta-carotene) vitamin A may interfere with the benefits of vitamin D, yet most multivitamins contain between 5,000 and 25,000 IU of preformed vitamin A.171

Cyanidin-3-glucoside (C3G)

Life Extension Mix™ contains 1.25 mg of C3G to support eye health. Found in blackberries and black currants, this potent compound promotes healthy levels of rhodopsin — a compound that absorbs light in the retina — and enhance night vision.172-176

In one study, just 50 mg of a berry extract concentrate containing C3G helped aging individuals see better in the darkness after 30 minutes.177 Bioavailable C3G also supports other body functions, 178-191 has potent antioxidant properties,192,193 and supports endothelial cell health.194,195

5-MTHF (5-methyltetrahydrofolate)

Folate helps maintain homocysteine levels within the normal range. One dose of our formula contains 400 mcg of the bioactive 5-MTHF form of folate, which is up to 7 times more bioavailable than ordinary folic acid.

Selenium and Apigenin

Life Extension Mix™ contains three potent forms of selenium (SelenoExcell®, Se-methyl-selenocysteine, and sodium selenite). Also newly included is apigenin, a powerful bioflavonoid found in many vegetables and fruits which boosts cell protection.

Why choose Life Extension Mix™?

The ingredients in Life Extension Mix™ are based on over 35 years of clinical research, and we've selected the purest and most potent forms of plant extracts, vitamins, minerals, and other nutrients for maximum absorption. Discover the extensive benefits of Life Extension Mix™!

These statements have not been evaluated by the Food and Drug Administration.
These products are not intended to diagnose, treat, cure, or prevent any disease.

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Supplement Facts

Serving Size 8 tablets (per day)

Servings Per Container 30

Amount Per Serving

Vitamin A (as beta-carotene, acetate) (5,000 IU)

1500 mcg

Vitamin C (as calcium ascorbate, ascorbic acid, ascorbyl palmitate, magnesium ascorbate, niacinamide ascorbate, acerola extract)

970 mg

Vitamin D3 (as cholecalciferol) (2,000 IU)

50 mcg

Vitamin E (as D-alpha tocopheryl succinate, D-alpha tocopherol)

67 mg

Thiamine (vitamin B1) (as thiamine HCl)

125 mg

Riboflavin (vitamin B2) (as riboflavin, riboflavin 5’-phosphate)

50 mg

Niacin (as 60% niacinamide, 39% niacin, 1% niacinamide ascorbate)

862 mg

Vitamin B6 [as pyridoxal 5’-phosphate (100 mg), pyridoxine HCI (5 mg)]

105 mg

Folate (as L-5-methyltetrahydrofolate calcium salt)

400 mcg

Vitamin B12 (as methylcobalamin)

600 mcg


3000 mcg

Pantothenic acid (as D-calcium pantothenate with 5 mg pantethine)

600 mg

Calcium (as dicalcium phosphate, Ca ascorbate, D-calcium pantothenate, Ca D-glucarate)

500 mg

Iodine (as potassium iodide)

150 mcg

Magnesium (as magnesium oxide, citrate, arginate, glycinate, taurinate, ascorbate)

420 mg

Zinc (as zinc citrate, L-OptiZinc®3 zinc mono-L-methionine sulfate)

35 mg

Selenium [as sodium selenite, SelenoExcell®4 high selenium yeast, Se-methyl L-selenocysteine]

200 mcg

Copper (as TRAACS®12 copper bisglycinate chelate)

1 mg

Manganese (as manganese citrate, gluconate)

1 mg

Chromium [as Crominex®5 3+ chromium stabilized with Capros® amla extract (fruit), PrimaVie® Shilajit]

500 mcg

Molybdenum (as molybdenum amino acid chelate)

125 mcg

Potassium (as potassium citrate)

35 mg

Broccoli concentrate blend [broccoli powder, extract (sprout , floret, seed) (providing glucosinolates, sulforaphane), calcium D-glucarate]

725 mg

N-acetyl-L-cysteine (NAC)

600 mg

Decaffeinated green tea extract (leaf) [std. to 45% epigallocatechin gallate (EGCG)]

325 mg

Acerola extract 4:1 (berry)

300 mg


250 mg

Bitter orange citrus bioflavonoids (peel, fruit) [std. to 50% hesperidin]

200 mg

Fruit/berry proprietary blend [European elder, blackberry, blueberry, sweet cherry, cranberry, plum, persimmon (Diospyros kaki) powders]

200 mg


200 mg

Wild blueberry anthocyanin extract (fruit)

150 mg

Sensoril®11 Ashwagandha extract (root, leaf) [std. to 32% oligosaccharides, 10% glycoside conjugates]

125 mg

Silymarin [from milk thistle extract (seed)]

100 mg

Trimethylglycine (TMG) (as betaine anhydrous)

100 mg

CherryPure®1 sour cherry (tart cherry) proanthocyanidin extract (skin)

85 mg

POMELLA®9 pomegranate extract (fruit) [std. to 30% punicalagins]

85 mg

Natural mixed tocopherols (providing gamma, delta, alpha, beta tocopherols)

60 mg

MirtoSelect®10 bilberry extract (fruit)

30 mg

BioVin®7 grape proanthocyanidin extract (whole grape)

25 mg

Leucoselect®6 grape seed proanthocyanidin extract

25 mg

Bio-Quercetin phytosome (providing 5 mg quercetin [from Japanese sophora concentrate (flower bud)], phosphatidylcholine complex [from sunflower])  15 mg 

Bromelain [from pineapple (stem)] (2400 gelatin digestive units/gram)

15 mg

Lutein [from marigold extract (flower)] (providing 465 mcg trans-zeaxanthin)

15 mg

Olive extract (fruit) (providing polyphenols, hydroxytyrosol, tyrosol, oleuropein)

12.5 mg

Sesame seed lignan extract

10 mg

Luteolin [from orange extract (fruit)]

8 mg


5 mg

Boron (as boron amino acid chelate)

3 mg

Lycopene [from LycoBeads®8 natural tomato extract (fruit)]

3 mg

Delphinidins [from Delphinol®2 maqui berry (Aristotelia chilensis) extract (fruit)]

2 mg

Cyanidin-3-glucoside (C3G) [from black currant extract (fruit)]

1.25 mg

Other ingredients: microcrystalline cellulose, maltodextrin, stearic acid, croscarmellose sodium, silica, vegetable stearate, starch, aqueous film coating (purified water, hydroxypropyl methylcellulose, glycerin).

1- CherryPure® is a registered trademark of Shoreline Fruit, LLC.
2- Delphinol® is a registered trademark of MNL.
3- L-OptiZinc® and logo are trademarks of Lonza or its affiliates.
4- SelenoExcell® is a registered trademark of Cypress Systems Inc.
5- Crominex® 3+, Capros® and PrimaVie® are registered trademarks of Natreon, Inc.
6- Leucoselect® is a registered trademark of Indena S.p.A.
7- BioVin® is a registered trademark of Cyvex Nutrition dba Bioriginal.
8- Lycored LycopeneTM is a registered trademark of Lycored; Orange, New Jersey.
9- POMELLA® Extract is covered under U.S. Patent 7,638,640 and POMELLA® is a registered trademark of Verdure Sciences, Inc.
10- MirtoSelect® is a registered trademark of Indena, S.p.A., Milan, Italy.
11- Sensoril® is protected under US Patent Nos. 6,153,198 and 6,713,092 and is a registered trademark of Natreon, Inc.
12- TRAACS® is a registered trademarks of Albion Laboratories, Inc.

Dosage and Use
  • Take (8) tablets daily in divided doses with meals, or as recommended by a healthcare practitioner.

Temporary flushing, itching, rash, or gastric disturbances may occur. Liver function testing is recommended when niacin is taken in excess of 500 mg daily. Those with gout or liver diseases should avoid taking high doses of niacin. Consult with your doctor before using this product if you are taking anticoagulant medications. Individuals consuming more than 2,000 IU/day of vitamin D (from diet and supplements) should periodically obtain a serum 25-hydroxy vitamin D measurement. Vitamin D supplementation is not recommended for individuals with high blood calcium levels. Individuals with in-born errors of copper metabolism (e.g. Wilson’s disease) should avoid daily, chronic use of this product.



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