Many who have greater need of supplements are least likely to use them

April 05, 2004

To our readers: We recently determined that a number of individuals who had signed up for Life Extension Update over the past several months had not been added to our subscriber list. If this is your first time receiving Life Extension Update, we would like to welcome you and ask that you accept our apologies for the delay. If you believe that you have received Life Extension Update in error, please follow the instructions for unsubscribing located at the bottom of this newsletter.

In this issue

Life Extension Update Exclusive:

Many who have greater need of supplements are least likely to use them


Cardiovascular disease

Featured Products of the Week:

Super Booster softgels

Super CoQ10 with tocotrienols

Life Extension Blood Tests

Super Sale on all Lab Tests through June 14!

Life Extension Update Exclusive

Many who have greater need of supplements are least likely to use them
A study published in the April 2004 issue of the British Journal of Nutrition found that individuals at risk of primary or secondary cardiovascular disease are less likely to use nutritional supplements than those who are not at risk, despite the publicized benefits revealed by clinical trials.

British researchers analyzed questionnaires concerning dietary supplement use, general health, lifestyle behaviors, past and current illnesses, prescription drug use, dietary habits and demographic information that were completed by 15,465 adult members of the general population. They found that over a third of the respondents were using at least one dietary supplement. There was a positive correlation observed between taking supplements and self-rated health. Supplement use was greater among older individuals, women, Caucasians, nonsmokers, homeowners, and people who reported greater levels of physical activity. Individuals who reported a history of heart attack, stroke, angina or hypertension were less likely to be using vitamin and/or mineral supplements than those who did not report any of these conditions. Arthritis, backache or sciatica suffers were more likely to be consumers of fish oil supplements.

The researchers concluded that individuals usng any supplements had a reduced likeliness of a current or past chronic disease or acute event. The only health problem for which a positive association with the use of supplements was found was musculoskeletal disease associated with fish oil, the use of which has been supported by clinical trials. This suggests that people with or at risk of coronary heart disease are less likely to have positive care-seeking behaviors than those who have arthritis, which in itself could contribute to the disease because of its association with unhealthy lifestyles. The authors “would like to see local healthcare providers develop policies regarding the use of dietary supplements and to disseminate this information to consumers.”


Cardiovascular disease
Cardiovascular disease is rarely caused by a single frailty. Rather, it is a multifaceted failure that includes physical, psychological, and genetic weaknesses. Since cardiovascular disease remains the number one killer in Western societies, there is more published scientific information about its prevention and treatment than exists for other diseases. Overlooking just one risk factor, such as elevated levels of C-reactive protein, fibrinogen, or homocysteine, could lead to the development or worsening of the heart and/or vascular disease.

Researchers reporting in the American Journal of Critical Care further unsettled the scientific community when they declared that 50% of patients with coronary artery disease do not have any of the traditional risk factors (Futterman et al. 1998). In fact, 50% of all individuals 50 years or younger who die from heart disease succumb without any established signs of heart disease. Does this mean that traditional risk factors are no longer valid? The intent of this material is to answer that question by providing a comprehensive review of contemporary and novel risk factors that contribute to cardiovascular disease and a complete dialogue regarding treatment options available to patients.

Laboratory testing to determine values of traditional and newer risk factors are valuable to all age groups. Tests are essential in preventive programs and as a means of monitoring progress for those with established cardiovascular disease. Be sure that you are being tested using the latest in screening tools, that is, technology capable of measuring the smaller, denser LDL particles (the form most susceptible to oxidation) and high sensitivity CRP screening.

Featured Products of the Week

Super Booster softgels

Super Booster contains gamma-tocopherol and tocotrienols, critical fractions of vitamin E that must be formulated in an oil base. Newer research has shown that these two compounds may be even more effective than the alpha-tocopherol found in powdered multi-vitamin mixes. Another important reason to consume the gamma fractions of vitamin E is that alpha-tocopherol can displace gamma-tocopherol in the body, resulting in reduced protection against free-radical assault. The tocotrienols and gamma tocopherol fractions of vitamain E provide complementary benefits because they are effective on different physiologic functions.

Super Booster provides pharmaceutical potencies of a wide range of health protecting nutrients. A capsule of Super Booster provides 100 mg of chlorophyllin, a water-soluble form of chlorophyll that has potent DNA protecting properties. When taken with the heaviest meal of the day, chlorophyllin can help to neutralize potentially toxic ingested substances. The ginkgo extract provides 120 milligrams of a 28/7 standardized flavonoid ratio, more than conventional ginkgo extracts. Ginkgo flavonoids are known to strengthen capillaries, which can improve blood flow to the brain, helping to maintain cognitive health. Vitamin K (K1 and K2 ) regulates calcium metabolism in the body by keeping calcium in the bones and off of arterial walls. Super Booster provides the ideal daily dose of 10 mg of vitamin K.

For added protection from the cumulative effects of free-radical damage, Super Booster contains the proven antioxidants lutein, selenium and lycopene. The mineral selenium contributes to DNA repair, immune function, and cellular detoxification. Lycopene may be the most effective of all the carotenoids, providing antimutagenic and cardio-promoting benefits.

Super CoQ10 with tocotrienols

Orally administered coQ10 goes directly to the mitochondria where it works to regulate the oxidation of fats and sugars into energy—an important function since the natural production of coQ10 declines with advancing age. When the body has an ample amount of coQ10 the mitochondria can work most efficiently throughout the entire body, in cells everywhere, including the most densely populated area, the heart.

When coQ10 is orally administered, it is absorbed through the lymphatic canals and distributed throughout the body. Coenzyme Q10 should be taken with some form of fat, since absorption through the lymphatic canals is greatly enhanced in the presence of dietary fat. It is for this reason that coQ10 offered by Life Extension is available in rice bran oil softgel capsules.

If you have questions or comments concerning this issue or past issues of Life Extension Update, send them to or call 954 766 8433 extension 7716.

For longer life,

Dayna Dye
Editor, Life Extension Update
Life Extension Foundation
1100 West Commercial Blvd
Fort Lauderdale, FL 33309
954 766 8433 extension 7716
Sign up for Life Extension Update at

Help spread the good news about living longer and healthier – forward this email to a friend!