Supplement use associated with positive health status and healthy behaviors

July 2, 2005 Printer Friendly
In this issue

Life Extension Update Exclusive:

Supplement use associated with positive health status and healthy behaviors


Cardiovascular disease

Featured Products:

Super Booster

Super EPA/DHA with Sesame Lignans & Olive Fruit Extract

Life Extension Magazine

July 2005 issue now online!

Life Extension Update Exclusive

Supplement use associated with positive health status and health-related behaviors

A study published in the July 2005 issue of the Journal of Nutrition ( found that nutritional supplement users in Britain have a greater number of positive health status indicators and health-related behaviors than men and women who don't use supplements.

Researchers at Cambridge University evaluated data from the MRC National Survey of Health and Development, a longitudinal study of 5,362 individuals born in Great Britain in 1946.  Information from the year 1999 was used for the current study, during which the participants were 53 years old.  Subjects were interviewed concerning alcohol consumption, physical activity, and smoking, and five day food diaries completed by the participants provided information on dietary and supplement intake.  Waist circumference, height, weight, and blood pressure were ascertained during physical examinations, and blood samples were measured for cholesterol, folate, iron and vitamin B12. 

Forty-five percent of the women and 25 percent of the men in the study reported using supplements.  Women were more likely to consume multinutrient supplements, vitamin E, GLA and vitamin B6, while a greater percentage of men than women reported using fish oil supplements. Men who reported participating in vigorous exercise were 50 percent more likely, and women 60 percent more likely to be supplement users than those who did who did not report this level of exercise.  Female nonsmokers were 50 percent more likely to use supplements than those who smoked.  Women who used supplements also had a lower body mass index, lower waist circumference, and greater plasma folate and vitamin B12 status than those who did not report using supplements.  Individuals with healthier diets that included cereals, fruit, yogurt, oily fish and olive oil were more often supplement users than those who did not consume these foods.

The results of the study show that there is a clustering of healthy behaviors and positive cardiovascular risk factors among some individuals, particularly women.  It also shows that those who could benefit the most from supplements may be the least likely to use them.


Cardiovascular disease

In the last 25 years, the incidence of coronary fatalities has decreased 33%. This is due largely to avoiding the traditional risk factors. Dr. Paul M. Ridker, M.D., M.P.H. (director of cardiovascular research at Brigham and Women's Hospital in Boston), speculates that an auxiliary list of newer predictive factors may significantly increase the numbers benefiting from 21st century diagnostics and treatment (Ridker 1999a).

For the past 20 years, eclectic physicians have judged Syndrome X to be a powerful indicator of an eventual heart attack. For clarity, let it be understood that a syndrome represents clusters of symptoms. In Syndrome X, the symptoms are an inability to fully metabolize carbohydrates; hypertriglyceridemia; reduced HDL levels; smaller, denser LDL particles; increased blood pressure; visceral adiposity; disrupted coagulation factors; insulin resistance; hyperinsulinemia; and, often, increased levels of uric acid.

Omega-3 fatty acids help maintain flexible cell membranes (Igal et al. 1997). This is important, for healthy membranes contain large numbers of insulin receptors, increasing the surface areas available for insulin binding. This is extremely important in diabetes and Syndrome X.

A number of studies have shown the protective value of fish consumption in regard to averting coronary heart disease and the incidence of sudden cardiac death. For example, a recent study reported data collected from the Physicians' Health Study involving more than 22,000 men followed over a 17-year time frame. Researchers tested the blood of 94 male study volunteers who experienced an episode of sudden cardiac death (but in whom there was no prior history of heart disease) against 184 matched control study participants who did not experience a cardiac event.

On an average, men who died suddenly had lower levels of omega-3 fatty acids. Among the men with the highest levels of omega-3 fatty acids in the blood, there was a 72% reduction in the risk of sudden cardiac death when compared to the men with the lowest levels of these substances in their blood (Albert et al. 2002; Wascher 2002).

To read the complete cardiovascular disease protocol, see

Featured Products

Super Booster

To reduce the cost and inconvenience of taking many different pills, Life Extension Super Booster provides optimal doses of ginkgo extract, vitamin K, chlorophyllin, lycopene, gamma-tocopherol, sesame, and other nutrients in just one capsule.

Ginkgo is the most popular flavonoid supplement in the world because of its multifaceted health effects. Vitamin K is found in vegetables and helps keep calcium in bones, while maintaining arterial structure and elasticity. Chlorophyllin is the most potent nutrient to protect gene health.

Lycopene continues to impress scientists as the red carotenoid that inhibits LDL oxidation and also protects DNA integrity. There are ten milligrams of lycopene in each capsule of the new Life Extension Super Booster.

Super EPA/DHA with Sesame Lignans & Olive Fruit Extract

Super EPA/DHA now has the nutrient powerhouses of sesame lignans and fortified extra virgin olive oil. To get this level of nutrients found in these high oils would require excessive consumption of the native oils adding many calories to the daily diet.

Polyphen-Oil™ Olive Fruit Extract is a proprietary, fortified extra virgin olive oil complex developed by Life Extension. The naturally occurring polyphenol antioxidants are typically lost in olive juice discarded during olive oil pressing. Polyphen-Oil™ is highly enriched oil with olive juice extract standardized with these naturally occurring antioxidants.

Life Extension Magazine

July 2005 issue now online!


On the cover: The disease-preventive power of the Mediterranean diet, by Dale Kiefer

Broad spectrum effects of grape seed extract, by Terri Mitchell

Advances in nutritional therapy for attention deficit hyperactivity disorder, by Laurie Barclay, MD

High blood sugar: Innovative strategies for supporting healthy metabolism, by Bruce Scali


As we see it: What do “regulated” supplements cost? By William Faloon

In the news: London conference touts benefits of lycopene, Vitamin E tocopherols reduce Alzheimer’s risk, Folate, vitamin B12 show added heart benefits, Green tea cuts prostate cancer risk, progression, Waist size predicts diabetes risk in men, Tomatoes protect against heart failure, Cranberries improve function in damaged blood vessels

All about supplements: PPC, a key nutrient that facilitates crucial cellular process, by Bradley Bongiovanni, ND

Case history: Therapeutic options for fibromyalgia, by Dr Sergey A Dzugan

Ask the doctor: Nutritional strategies for promoting optimal oral health, by Nelson Wood, DMD, DSc, MS

Profile: Pat Walter, a guide to navigating America’s cancer care system, by Sue Kovach

July 2005 abstracts: Mediterranean diet, ADHD, grape seed extract, diabetes, and fibromyalgia

Questions? Comments? Send them to or call 1-800-678-8989.

For longer life,

Dayna Dye
Editor, Life Extension Update
1100 West Commercial Boulevard
Fort Lauderdale FL 33309
954 766 8433 extension 7716

Sign up for Life Extension Update at

Help spread the good news about living longer and healthier. Forward this email to a friend!

View previous issues of Life Extension Update in the Newsletter Archive.