Newsletter

Newsletter

Vitamin D Deficiency More Common In Arteriogenic ED Patients

Vitamin D deficiency more common in arteriogenic ED patients

Life Extension Update

Tuesday, August 26, 2014. An article published online on August 5, 2014, in the Journal of Sexual Medicine reports the finding of researchers from Milan, Italy, of an association between reduced vitamin D levels and a greater risk of erectile dysfunction (ED) caused by arterial factors.

The current study included 50 middle-aged men diagnosed with arteriogenic erectile dysfunction, 28 with borderline ED, and 65 with nonarteriogenic ED as determined by penile echo-color Doppler. Blood samples were analyzed for serum 25-hydroxyvitamin D levels and other factors.

Deficient vitamin D levels, defined by the authors of this study as less than 20 nanograms per milliliter (ng/mL), were uncovered in 45.9% of the participants. Severe deficiency, characterized by a level of less than 10 ng/mL, was observed in 5.6% of the group. Among those with deficient vitamin D levels, 38.6% had complete or severe ED, in comparison with 25.3% of nondeficient men.

In those with arteriogenic ED, vitamin D levels were significantly lower on average in comparison with the borderline and nonarteriogenic ED groups. Sixty-one percent of those with arteriogenic ED were vitamin D deficient in comparison with 30% of the borderline group and 42% of the men with nonarteriogenic ED. Among those with vitamin D levels lower than 20 mg/mL, the prevalence of arteriogenic ED was 45.6%, versus 22.3% in those with higher vitamin levels.

Authors Alessandra Barassi, MD, and her colleagues remark that ED may appear years before cardiovascular disease is diagnosed, possibly due to the smaller size of the arteries involved. "Low vitamin D levels may be an independent, potentially modifiable ED risk factor, particularly for dysfunction of arteriogenic etiology," they write. "We suggest routine measurement of vitamin D in ED patients, with replacement therapy as required."

 
What's Hot
Lifestyle improvements and heart disease treatment may be better than drugs for ED

What's Hot

The results of a review published September 12, 2011, online in the Archives of Internal Medicine reveal that engaging in beneficial lifestyle practices and obtaining treatment for cardiovascular disease risk factors significantly improve erectile dysfunction (ED) in middle aged men. The meta-analysis is the first, to the author's knowledge, to evaluate the effect of lifestyle interventions and cardiovascular risk factor reductions on the condition.

Researchers at the Mayo Clinic in Rochester, Minnesota, selected six randomized clinical trials that included a total of 740 men with an average age of 55.4 years for their analysis. The trials evaluated the effects of exercise and lifestyle change, a Mediterranean diet, an interval exercise program, weight loss, and treatment with the drug atorvastatin on cardiovascular risk factors. Erectile dysfunction was evaluated via questionnaire responses.

The analysis affirmed that improvements in cardiovascular risk factors were associated with a reduction in erectile dysfunction. Separate analyses of lifestyle and drug treatment were also both associated with a significant benefit.

"Therapies currently used for the treatment of ED include oral therapy with phosphodiesterase type 5 (PDE-5) inhibitors, which are highly effective in the treatment of ED," the authors write. "However, we demonstrate that cardiovascular risk factor reduction improves ED even in men who are not responsive to PDE-5 inhibitors."

"Our findings suggest that cardiovascular risk factor reduction provides incremental benefits in ED well beyond that achieved with the use of PDE-5 inhibitors," they add. "Adoption of lifestyle modifications and cardiovascular risk factor reduction will provide incremental benefit regardless of PDE-5 inhibitor use."

 

Life Extension Clinical Research Update
Support Male Sexual Health

Study Objective: Assess the effect of a nutritional supplement for male sexual health over the course of 30 days.

To Qualify:

  • You must be between 50 and 70 years of age.
  • Be in a stable sexual relationship for at least 6 or more months.
  • Able to comply with all study procedures and visits.

Your Involvement:

  • You will make 3 visits over 30 days.
  • You will receive the nutritional supplement to be studied, blood pressure evaluations, and blood tests including a male hormone panel.
  • Upon successful completion of the trial, you will be compensated for time and travel up to $100.

Register For This Study
Or call 1-866-517-4536

If qualified you will receive:

  • Study product
  • Blood tests including a Male Hormone Panel.
  • Blood pressure evaluations
  • Up to $100 for time and travel expenses
  • Referral bonus available: $50

https://www.lifeextension.com/clinicalresearch/ClinicalTrials.htm

Health Concern

Erectile Dysfunction

Mega Green Tea Extract 

It is important for men suffering from erectile dysfunction to discuss their symptoms with their physician (Hackett 2009). In addition to recommending an effective treatment for the primary complaint of erectile dysfunction, physicians should also screen for cardiovascular disease (CVD) (Nehra 2012; Sadeghi-Nejad 2007; NIH 1992).

This is because erectile dysfunction and CVD share similar risk factors, including aging, hypertension, obesity, and a sedentary lifestyle (Hannan 2009; Ewane 2012; Nunes 2012). Furthermore, erectile dysfunction itself has been shown to independently increase the risk of CVD, stroke, and all-cause death (Kolodny 2011; Heidelbaugh 2010). Since erectile dysfunction often precedes some cardiovascular events by 2–5 years (Nehra 2012), erectile dysfunction is viewed as a potential early warning sign for CVD (Meldrum 2011). Early detection is critical since CVD is a major cause of disability and death (Ewane 2012). The abbreviation "ED" can help make this issue easy to understand and remember. For instance, "ED" stands not only for "Erectile Dysfunction", but also "Endothelial Dysfunction", "Exercise & Diet" (for prevention), and "Early Detection" of risk factors, which can help avoid "Early Death" due to CVD (Jackson 2006).

Read More
 
 
Latest Products
Mega Green Tea Extract

Tart Cherry Extract, 60 vegetarian capsules

Item #01723
Add to Cart

With nearly 40 scientific studies published on the wide-ranging benefits of tart cherries, scientists are now discovering important new health applications for this American fruit. Tart cherries are packed with unique beneficial compounds that have been shown to block COX-1 and COX-2 enzymes, as well as maintain muscle function and promote rapid muscle recovery after exercise, bringing faster relief from the minor aches, discomfort, and stiffness that can follow everyday muscle exertion.

Anthocyanins are powerful molecules that provide the dark pigmentation to blueberries, raspberries, and bilberries. In addition to being potent antioxidants, anthocyanins have been extensively studied for their numerous health benefits that include heart, cellular, and cognitive health.

What has drawn the attention of scientists is the fact that tart cherries not only contain a higher content of anthocyanins than other fruits, they also contain unique anthocyanins not found in other berries.

Mega Green Tea Extract

Unleash the Power of the Female Brain, by Daniel G. Amen, M.D.

Item #33869
Add to Cart

Unleash the Power of the Female Brain: Supercharging Yours for Better Health, Energy, Mood, Focus, and Sex is a guide on how to strengthen, optimize and heal the most important part of you: your brain. Specifically you will learn how to harness the unique strengths of the female brain — intuition, collaboration, empathy, and a little worry — and how to overcome some of its inherent vulnerabilities, such as depression and being unable to turn your brain off.

The book will help you end the confusion regarding hormones, get your cravings under control, no matter where you are in your cycle, and optimize your brain for love, sex and relationships. Plus, the book will help you get your brain ready for babies, and give you insight into how to raise them in a brain healthy way. It will give you 12, simple hour-long exercises to assess, train, and strengthen your brain. It's the only owner's manual you will ever need for your female brain.

 
Related Life Extension® Magazine Articles
The Truth About Male
and Female Sexual Dysfunction
The Intimate Link Between Erectile Dysfunction and Heart Disease