Asthma benefit for vitamin C

An article published on August 25, 2011 in Clinical and Translational Allergy reports a positive effect for vitamin C supplementation in asthmatic children.

In a cross-over trial, 60 children between the ages of 7 and 10 with asthma were given 200 milligrams vitamin C, zinc, omega-3 fatty acids, a combination of the three supplements or a placebo daily for six weeks. After a two week period during which no supplements were given, the participants were switched to a new regimen, until all children had received each treatment. Questionnaires assessed asthma severity at the beginning of the study and at the end of each phase of treatment, and pulmonary function was tested via spirometry. Additionally, the parents were questioned on the presence of mold or dampness in the children's bedrooms.

While supplementation with vitamin C was associated with an average increase of 29 percent in forced expiratory volume per one second (FEV1), which is a measure of pulmonary function, there was significant difference among the participants according to age and level of mold exposure. Children aged 7 to 8.2 years who had no exposure to dampness or mold experienced a 37 percent increase FEV1, while this measure increased by just 21 percent in those between the ages of 8.3 and 10 years whose parents reported mold and dampness in their children's rooms. When symptom questionnaire responses were analyzed, children aged 7 to 8.2 years with mild asthma symptoms were found to have experienced the greatest benefit from the vitamin, while older subjects whose symptoms were severe benefitted least. "It would seem important to carry out further research to confirm our findings and more accurately identify the groups of children who would receive the greatest benefit from vitamin C supplementation," the authors write.

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