Glucosamine Chondroitin MSM with Ester-C®

  • 180 tablets
  • Item # 26703

Glucosamine Chondroitin MSM with Ester-C®

  • 180 tablets
  • Item # 26703

Glucosamine, Chondroitin, MSM with Ester-C by Solgar is a combination of four nutrients that play a role in joint health.

Benefits at a Glance:

  • Supports joint health
  • Supports a healthy level of inflammation
  • Helps maintain joint comfort

Glucosamine is a sugar found in cartilage, the substance that composes our joints. Glucosamine is used in the construction of glycosaminoglycans that help cushion the joints. Glucosamine also inhibits cartilage-damaging enzymes.1

The synthesis of glucosamine by the body’s chondrocytes may become deficient as we age. A meta-analysis of 18 randomized trials that evaluated the effects of glucosamine on knee osteoarthritis concluded that glucosamine is superior to a placebo to alleviate symptoms.2

Chondroitin sulfate is a glycosaminoglycan occurring in cartilage.3 It helps maintaining structural integrity and slows cartilage breakdown. A meta-analysis of 43 randomized trials involving patients with osteoarthritis that included a total of 4,962 participants treated with chondroitin and 4,148 control participants determined that chondroitin was associated with better pain relief than a placebo in short term studies.4

Methylsulfonylmethane (MSM) is a naturally occurring compound that is a sulfur donor. Because sulfur levels in the cartilage of people with arthritis are approximately one-third of levels occurring in those without the condition, MSM may be useful for this group of patients.5 Methylsulfonylmethane also helps support normal levels of inflammation.6

Ester-C is a form of vitamin C known as calcium ascorbate. When bound to minerals, the natural acidity of vitamin C (ascorbic acid) becomes neutralized, making it less likely to irritate the digestive tract. Vitamin C plays a role in the synthesis of collagen that makes up cartilage.7 In a randomized, double-blind trial, calcium ascorbate was superior to a placebo in the relief of pain in individuals with osteoarthritis of the hip or knee.8

Together, these ingredients help support and maintain healthy joints.

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Frequently Bought Together

  • This Item: Glucosamine Chondroitin MSM with Ester-C®, 180 tablets
  • Pycnogenol®, 100 mg, 60 vegetarian capsules

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  1. Piperno M et al. Osteoarthritis Cartilage. 2000 May;8(3):207-12.
  2. Ogata T et al. Clin Rheumatol. 2018 Sep;37(9):2479-2487.
  3. Bishnoi M et al. Glycoconj J. 2016 Oct;33(5):693-705.
  4. Singh JA et al. Cochrane Database Syst Rev. 2015 Jan 28;1:CD005614.
  5. Rizzo R et al. J Exp Zool. 1995 Sep 1;273(1):82-6.
  6. Butawan M et al. Nutrients. 2017 Mar 16;9(3):290.
  7. Rowe DJ et al. J Periodontol. 1999 Sep;70(9):992-9.
  8. Jensen NH et al. Ugeskr Laeger. 2003 Jun 16;165(25):2563-6.

Serving Size 3 Tablets

Servings Per Container 60

Amount Per Serving



Total Carbohydrate

3 g

Vitamin C (as Ester-C®, calcium ascorbate)

60 mg


120 mg

Glucosamine Sulfate (from Glucosamine Sulfate 2KCI)

1500 mg

Sodium Chondroitin Sulfate 1200 mg

MSM (as methylsulfonylmethane) (as OptiMSM®)

700 mg

Other ingredients: Vegetable stearic acid, vegetable cellulose, silica, vegetable magnesium stearate, vegetable glycerin.
Contains shellfish (crab, crayfish, lobster, shrimp).

Naturally occurring.

Free of gluten, wheat, yeast, sugar, artificial flavors, artificial sweeteners, artificial preservatives, artificial colors.

Dosage and Use
  • As a dietary supplement for adults, take three (3) tablets daily, preferably with a meal or as directed by a healthcare practitioner.

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