Supplementing With Calcium And Vitamin D Associated Lower Risk Of Dying Over Three Year Period

Supplementing with calcium and vitamin D associated with lower risk of dying over three year period

Supplementing with calcium and vitamin D associated with lower risk of dying over three year period

Tuesday, June 19, 2012. A article published in the Journal of Clinical Endocrinology and Metabolism reveals the outcome of a pooled analysis of eight randomized controlled trials which suggests that the use of calcium and vitamin D supplements reduced mortality over an average three year period.

Lars Rejnmark, PhD of Aarhus University Hospital in Denmark and his colleagues evaluated mortality among clinical trial participants assigned to calcium with vitamin D or vitamin D alone. Each trial included over 1,000 women and men who had a median age of 70 years. Dr Rejnmark's team found a 9 percent lower risk of dying over an average of three years in subjects who consumed calcium with vitamin D in comparison with those who did not receive the combination. The reduction in risk was not solely attributable to a decrease in fractures.

"This is the largest study ever performed on effects of calcium and vitamin D on mortality," Dr Rejnmark announced. "Our results showed reduced mortality in elderly patients using vitamin D supplements in combination with calcium, but these results were not found in patients on vitamin D alone."

"Some studies have suggested calcium (with or without vitamin D) supplements can have adverse effects on cardiovascular health," he noted. "Although our study does not rule out such effects, we found that calcium with vitamin D supplementation to elderly participants is overall not harmful to survival, and may have beneficial effects on general health".

What's Hot Highlight

Reduced vitamin D levels associated with obesity

What's Hot

An article published online on February 6, 2012 in the American Journal of Epidemiology reveals an association between decreased serum vitamin D levels and a greater incidence of obesity in adults.

Xiao-Mei Mai of Norwegian University of Science and Technology and colleagues evaluated data from 2,460 men and women aged 19 to 55 who participated in the second and third surveys of the Nord-Trøndelag Health Study, conducted between 1995 to 1997 and 2006 to 2008. Serum 25-hydroxyvitamin D levels and anthropometric measurements were obtained upon enrollment and at follow up.

Twelve percent of the subjects were classified as obese [defined as having a body mass index (BMI) of 30 or more] at the beginning of the study and 15 percent were classified as obese after 11 years of follow-up. Having a serum vitamin D level below 50 nmol/L was associated with a four times greater adjusted risk of obesity than that experienced by subjects whose levels were 75 nmol/L or higher at the beginning of the study, and with a 1.73 times greater risk of developing obesity over follow-up. Similar results were observed when waist circumference was used to classify obesity, indicating an association with central adiposity.

"Our study is one of the few prospective cohort studies to have investigated the possible effect of low vitamin D status on change in adiposity and development of obesity," the authors write. "We found a consistent inverse association between baseline 25-hydroxyvitamin D levels and incident obesity defined by either BMI or waist circumference after 11 years of follow-up, and this inverse association was not modified by season of blood sample collection."

They recommend large prospective studies to further investigate the relationship between low vitamin D levels and the development of obesity.

About Life Extension

The Life Extension Foundation Buyers Club is an organization whose long-range goal is the extension of the healthy human life span. In seeking to control aging, our objective is to develop methods to enable us to live in vigor, health and wellness for an unlimited period of time. Life Extension® was established in the early 1980s, but its founders have been involved in the anti- aging field since the 1960s. Life Extension publishes the very latest information on anti-aging and wellness in its monthly publication, Life Extension Magazine®, the Disease Prevention and Treatment book of integrative health protocols, the Life Extension Update e-mail newsletter and the Daily Health Bulletin, and on this website--all to support more informed health choices.

The Life Extension Foundation is the world's largest membership organization dedicated to investigating every method of extending the healthy human life span and funding anti-aging research. When seeking methods to slow aging, the non-profit Life Extension Foundation often uncovers potential therapies to fight the conditions associated with aging.

What began as a newsletter over 30 years ago has evolved into a total health offering, including:

  • The full-color monthly Life Extension Magazine that reports on the latest health and wellness research.
  • An staff of advisors (naturopaths, nutritionists, nurses, personal trainers, and other health professionals) available every day to answer your health questions and concerns, and to assist you in formulating your personal regimen of diet, exercise and supplements.
  • Access to 300+ top-quality Life Extension products plus 2,000 other health-related products.
  • A 24/7/365 call center for ease of ordering (or the convenience of shopping online)
  • A mail-order blood testing service that costs a fraction of what commercial blood labs charge, with blood draws performed in a convenient local LabCorp facility near you (some restrictions apply).
  • Access to the independent, full-service Life Extension Pharmacy™, including compounded prescriptions, offering a unique knowledge of pharmaceuticals and nutraceuticals, as well as remarkable prescription savings.

Learn how you can access all of the above services, as well as receive discounts on dietary supplements and blood testing, by joining the Life Extension Foundation.

Latest Supplements

Stem Cell Cream with Alpine Rose
Item #80143

add to cart

Years of combating the elements and resisting the effects of pollution, stress, sun exposure (UV) and other toxins take their toll on the epidermal stem cells—the cells involved in skin repair and renewal. Researchers have found that applying selected plant stem cell extracts to the skin, specifically those cultured from the alpine rose, offers protection to the epidermal stem cells, prolonging their lives, increasing their colony-forming efficiency and enhancing their function.

A potent new cream, containing the stem cells of alpine rose leaves, is now available to help preserve, protect and stimulate your skin's stem cells. Also included in the formula are other skin saving compounds, including an extract of Chondrus crispus, a red seaweed found only in the cold waters off the Atlantic coast. With its abundant mineral salts, trace elements, proteins, and vitamins, this extract is an excellent emollient with soothing properties.

Mega L-Glutathione Caps
Item #00314

add to cart

Glutathione (gamma-L-glutamyl-L-cysteinyl-glycine) is a peptide (short protein)-like molecule synthesized in the body from the three amino acids L-glutamic acid, L-cysteine, and glycine. Glutathione is one of the body's most important and powerful antioxidants, helping to detoxify xenobiotics. A major function of vitamin C is to keep glutathione in its reduced form so that they can continue to provide free radical quenching effects.

Even though many published studies show that garlic, selenium, alpha-lipoic acid, L-cysteine, and N-acetylcysteine can boost cellular glutathione levels, people with health problems may benefit from taking high doses of glutathione.



Life Extension Update What's Hot
Meta-analysis associates reduced vitamin D levels with greater risk of dying over follow-up periods of up to 27 years Higher vitamin D levels predict longer intensive care survival
Review finds improved survival in clinical trials of vitamin D3 supplementation Higher vitamin D levels in men and women with metabolic syndrome associated with reduced mortality over seven years
Increased calcium intake associated with lower mortality from all causes over 10 year period Higher vitamin D levels predict improved survival among colorectal cancer patients
Life Extension Magazine® Health Topics
Flawed analysis misleads public about calcium and heart attack risk Osteoporosis
Millions of needless deaths Prevention protocols
Osteoporosis: how calcium combines with other nutrients to combat bone loss Atherosclerosis and cardiovascular disease