- Science & Research
- Magazine
- 2025
- November
November Life Extension Magazine®
In a clinical trial of aging men and women, two plant extracts boosted vitality and muscle strength.
Reports
Curb Hunger to Lose Weight
In a clinical trial of overweight adults, taking a blend of plant extracts, along with a modest diet and exercise program, led to close to 5% weight loss in just two months.
Little-Known Nutrient for Healthier Aging
L-ergothioneine, an amino acid found in mushrooms, was shown in preclinical research to protect telomeres. In human trials, L-ergothioneine improved cognitive ability and cardiometabolic function.
Reduce Nighttime Bathroom Visits
In a clinical trial, a combination of five compounds helped reduce nocturia symptoms in men. After 60 days, not a single subject reported waking more than once a night to urinate.
Reduce Migraine Symptoms
Six nutrients in separate clinical trials decreased frequency, duration, and severity of migraine headaches and reduced the need for migraine medications.
Improving Brain Aging with Senolytics
A recent article in the journal Neuron linked immune dysfunction with cognitive decline. Preclinical data suggests that senolytic compounds remove senescent cells, helping to potentially protect the aging brain and improve some immune functions.
Departments
As We See It: Tribute to A Life-Saving Pioneer
When Harvard scientist Kilmer McCully identified elevated homocysteine as a cardiovascular risk factor, his findings were rejected for many years.
In the News: Folic Acid and Vitamin B12 Could Help Protect Against Intracranial Aneurysms
Folic acid and vitamin B12 may protect against intracranial aneurysms